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Items: 1 to 20 of 132

1.

The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.

Omenetti A, Popov Y, Jung Y, Choi SS, Witek RP, Yang L, Brown KD, Schuppan D, Diehl AM.

Gut. 2008 Sep;57(9):1275-82. doi: 10.1136/gut.2008.148619. Epub 2008 Mar 28.

PMID:
18375471
2.

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.

Omenetti A, Porrello A, Jung Y, Yang L, Popov Y, Choi SS, Witek RP, Alpini G, Venter J, Vandongen HM, Syn WK, Baroni GS, Benedetti A, Schuppan D, Diehl AM.

J Clin Invest. 2008 Oct;118(10):3331-42. doi: 10.1172/JCI35875.

3.

Hedgehog activity, epithelial-mesenchymal transitions, and biliary dysmorphogenesis in biliary atresia.

Omenetti A, Bass LM, Anders RA, Clemente MG, Francis H, Guy CD, McCall S, Choi SS, Alpini G, Schwarz KB, Diehl AM, Whitington PF.

Hepatology. 2011 Apr;53(4):1246-58. doi: 10.1002/hep.24156.

4.

Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells.

Witek RP, Yang L, Liu R, Jung Y, Omenetti A, Syn WK, Choi SS, Cheong Y, Fearing CM, Agboola KM, Chen W, Diehl AM.

Gastroenterology. 2009 Jan;136(1):320-330.e2. doi: 10.1053/j.gastro.2008.09.066. Epub 2008 Oct 7.

5.

Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.

Omenetti A, Yang L, Li YX, McCall SJ, Jung Y, Sicklick JK, Huang J, Choi S, Suzuki A, Diehl AM.

Lab Invest. 2007 May;87(5):499-514. Epub 2007 Mar 5.

6.

Effects of selective bile duct ligation on liver parenchyma in young animals: histologic and molecular evaluations.

Tannuri AC, Coelho MC, de Oliveira Gonçalves J, Santos MM, Ferraz da Silva LF, Bendit I, Tannuri U.

J Pediatr Surg. 2012 Mar;47(3):513-22. doi: 10.1016/j.jpedsurg.2011.10.009.

PMID:
22424347
7.

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells.

Yang L, Wang Y, Mao H, Fleig S, Omenetti A, Brown KD, Sicklick JK, Li YX, Diehl AM.

J Hepatol. 2008 Jan;48(1):98-106. Epub 2007 Oct 18.

8.

Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.

Syn WK, Jung Y, Omenetti A, Abdelmalek M, Guy CD, Yang L, Wang J, Witek RP, Fearing CM, Pereira TA, Teaberry V, Choi SS, Conde-Vancells J, Karaca GF, Diehl AM.

Gastroenterology. 2009 Oct;137(4):1478-1488.e8. doi: 10.1053/j.gastro.2009.06.051. Epub 2009 Jul 3.

9.

Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.

Jung Y, Brown KD, Witek RP, Omenetti A, Yang L, Vandongen M, Milton RJ, Hines IN, Rippe RA, Spahr L, Rubbia-Brandt L, Diehl AM.

Gastroenterology. 2008 May;134(5):1532-43. doi: 10.1053/j.gastro.2008.02.022. Epub 2008 Feb 14.

10.

Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice.

Kennedy LL, Meng F, Venter JK, Zhou T, Karstens WA, Hargrove LA, Wu N, Kyritsi K, Greene J, Invernizzi P, Bernuzzi F, Glaser SS, Francis HL, Alpini G.

Lab Invest. 2016 Dec;96(12):1256-1267. doi: 10.1038/labinvest.2016.112. Epub 2016 Oct 24.

11.

Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells.

Fingas CD, Bronk SF, Werneburg NW, Mott JL, Guicciardi ME, Cazanave SC, Mertens JC, Sirica AE, Gores GJ.

Hepatology. 2011 Dec;54(6):2076-88. doi: 10.1002/hep.24588.

12.

Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation.

Xie G, Choi SS, Syn WK, Michelotti GA, Swiderska M, Karaca G, Chan IS, Chen Y, Diehl AM.

Gut. 2013 Feb;62(2):299-309. doi: 10.1136/gutjnl-2011-301494. Epub 2012 Feb 23.

13.

Role of hedgehog signalling in bile ductular cells.

Hines IN, Rippe RA.

Gut. 2008 Sep;57(9):1198-9. doi: 10.1136/gut.2008.153098. Review. No abstract available.

PMID:
18719134
14.

Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish.

Jung IH, Jung DE, Park YN, Song SY, Park SW.

PLoS One. 2011;6(12):e27941. doi: 10.1371/journal.pone.0027941. Epub 2011 Dec 2.

15.

Role for hedgehog pathway in regulating growth and function of invariant NKT cells.

Syn WK, Witek RP, Curbishley SM, Jung Y, Choi SS, Enrich B, Omenetti A, Agboola KM, Fearing CM, Tilg H, Adams DH, Diehl AM.

Eur J Immunol. 2009 Jul;39(7):1879-92. doi: 10.1002/eji.200838890.

16.

Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production.

Omenetti A, Syn WK, Jung Y, Francis H, Porrello A, Witek RP, Choi SS, Yang L, Mayo MJ, Gershwin ME, Alpini G, Diehl AM.

Hepatology. 2009 Aug;50(2):518-27. doi: 10.1002/hep.23019.

17.

Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.

Xie G, Karaca G, Swiderska-Syn M, Michelotti GA, Krüger L, Chen Y, Premont RT, Choi SS, Diehl AM.

Hepatology. 2013 Nov;58(5):1801-13. doi: 10.1002/hep.26511. Epub 2013 Sep 30.

18.

Sonic hedgehog mediates a novel pathway of PDGF-BB-dependent vessel maturation.

Yao Q, Renault MA, Chapouly C, Vandierdonck S, Belloc I, Jaspard-Vinassa B, Daniel-Lamazière JM, Laffargue M, Merched A, Desgranges C, Gadeau AP.

Blood. 2014 Apr 10;123(15):2429-37. doi: 10.1182/blood-2013-06-508689. Epub 2014 Jan 28.

19.

Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni.

Pereira TA, Xie G, Choi SS, Syn WK, Voieta I, Lu J, Chan IS, Swiderska M, Amaral KB, Antunes CM, Secor WE, Witek RP, Lambertucci JR, Pereira FL, Diehl AM.

Liver Int. 2013 Jan;33(1):149-61. doi: 10.1111/liv.12016. Epub 2012 Nov 1.

20.

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