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Items: 1 to 20 of 74

1.

Analysis of K-Ras phosphorylation, translocation, and induction of apoptosis.

Quatela SE, Sung PJ, Ahearn IM, Bivona TG, Philips MR.

Methods Enzymol. 2008;439:87-102. doi: 10.1016/S0076-6879(07)00407-7.

PMID:
18374158
2.

PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.

Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, Miura J, Wiener HH, Wright L, Saba SG, Yim D, Fein A, Pérez de Castro I, Li C, Thompson CB, Cox AD, Philips MR.

Mol Cell. 2006 Feb 17;21(4):481-93.

3.

Nonconventional trafficking of Ras associated with Ras signal organization.

Ashery U, Yizhar O, Rotblat B, Kloog Y.

Traffic. 2006 Sep;7(9):119-26. Review.

4.

The recruitment of Fas-associated death domain/caspase-8 in Ras-induced apoptosis.

Chen CY, Juo P, Liou JS, Li CQ, Yu Q, Blenis J, Faller DV.

Cell Growth Differ. 2001 Jun;12(6):297-306.

5.

Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.

Jang H, Abraham SJ, Chavan TS, Hitchinson B, Khavrutskii L, Tarasova NI, Nussinov R, Gaponenko V.

J Biol Chem. 2015 Apr 10;290(15):9465-77. doi: 10.1074/jbc.M114.620724. Epub 2015 Feb 24.

6.

Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch.

Ashery U, Yizhar O, Rotblat B, Elad-Sfadia G, Barkan B, Haklai R, Kloog Y.

Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):471-95. Epub 2006 May 12.

PMID:
16691442
7.

Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status.

Barceló C, Paco N, Beckett AJ, Alvarez-Moya B, Garrido E, Gelabert M, Tebar F, Jaumot M, Prior I, Agell N.

J Cell Sci. 2013 Oct 15;126(Pt 20):4553-9. doi: 10.1242/jcs.123737. Epub 2013 Aug 13.

8.

A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid.

Yart A, Roche S, Wetzker R, Laffargue M, Tonks N, Mayeux P, Chap H, Raynal P.

J Biol Chem. 2002 Jun 14;277(24):21167-78. Epub 2002 Mar 26.

9.

Activation of sterile20-like kinase 1 in proteasome inhibitor bortezomib-induced apoptosis in oncogenic K-ras-transformed cells.

Teraishi F, Guo W, Zhang L, Dong F, Davis JJ, Sasazuki T, Shirasawa S, Liu J, Fang B.

Cancer Res. 2006 Jun 15;66(12):6072-9.

10.

Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors.

Sung PJ, Tsai FD, Vais H, Court H, Yang J, Fehrenbacher N, Foskett JK, Philips MR.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20593-8. doi: 10.1073/pnas.1306431110. Epub 2013 Dec 2.

11.

Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival.

Carón RW, Yacoub A, Li M, Zhu X, Mitchell C, Hong Y, Hawkins W, Sasazuki T, Shirasawa S, Kozikowski AP, Dennis PA, Hagan MP, Grant S, Dent P.

Mol Cancer Ther. 2005 Feb;4(2):257-70.

12.

A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes.

Lu A, Tebar F, Alvarez-Moya B, López-Alcalá C, Calvo M, Enrich C, Agell N, Nakamura T, Matsuda M, Bachs O.

J Cell Biol. 2009 Mar 23;184(6):863-79. doi: 10.1083/jcb.200807186. Epub 2009 Mar 16.

13.

Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch.

Santy LC, Frank SR, Hatfield JC, Casanova JE.

Curr Biol. 1999 Oct 21;9(20):1173-6.

14.

K-Ras and H-Ras activation promote distinct consequences on endometrial cell survival.

Ninomiya Y, Kato K, Takahashi A, Ueoka Y, Kamikihara T, Arima T, Matsuda T, Kato H, Nishida J, Wake N.

Cancer Res. 2004 Apr 15;64(8):2759-65.

15.

N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization.

Cadwallader KA, Paterson H, Macdonald SG, Hancock JF.

Mol Cell Biol. 1994 Jul;14(7):4722-30.

16.

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway.

Mazzoni IE, Saïd FA, Aloyz R, Miller FD, Kaplan D.

J Neurosci. 1999 Nov 15;19(22):9716-27.

17.

Electrical properties of plasma membrane modulate subcellular distribution of K-Ras.

Gomez GA, Daniotti JL.

FEBS J. 2007 May;274(9):2210-28. Epub 2007 Mar 27.

18.
19.

H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.

Carón RW, Yacoub A, Zhu X, Mitchell C, Han SI, Sasazuki T, Shirasawa S, Hagan MP, Grant S, Dent P.

Mol Cancer Ther. 2005 Feb;4(2):243-55.

20.

Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways.

Ikeda M, Hirabayashi S, Fujiwara N, Mori H, Kawata A, Iida J, Bao Y, Sato Y, Iida T, Sugimura H, Hata Y.

Exp Cell Res. 2007 Apr 15;313(7):1484-95. Epub 2007 Feb 23.

PMID:
17367779

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