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Items: 1 to 20 of 100

1.

The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation.

Feng CG, Weksberg DC, Taylor GA, Sher A, Goodell MA.

Cell Stem Cell. 2008 Jan 10;2(1):83-9. doi: 10.1016/j.stem.2007.10.007.

2.

Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.

King KY, Baldridge MT, Weksberg DC, Chambers SM, Lukov GL, Wu S, Boles NC, Jung SY, Qin J, Liu D, Songyang Z, Eissa NT, Taylor GA, Goodell MA.

Blood. 2011 Aug 11;118(6):1525-33. doi: 10.1182/blood-2011-01-328682. Epub 2011 Jun 1.

3.

Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.

Feng CG, Collazo-Custodio CM, Eckhaus M, Hieny S, Belkaid Y, Elkins K, Jankovic D, Taylor GA, Sher A.

J Immunol. 2004 Jan 15;172(2):1163-8.

4.

Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy.

Presley CA, Lee AW, Kastl B, Igbinosa I, Yamada Y, Fishman GI, Gutstein DE, Cancelas JA.

Cell Commun Adhes. 2005 Jul-Dec;12(5-6):307-17.

PMID:
16531325
5.

The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death.

Feng CG, Zheng L, Jankovic D, Báfica A, Cannons JL, Watford WT, Chaussabel D, Hieny S, Caspar P, Schwartzberg PL, Lenardo MJ, Sher A.

Nat Immunol. 2008 Nov;9(11):1279-87. doi: 10.1038/ni.1653. Epub 2008 Sep 21.

6.

Delineating the effects of 5-fluorouracil and follicle-stimulating hormone on mouse bone marrow stem/progenitor cells.

Shaikh A, Bhartiya D, Kapoor S, Nimkar H.

Stem Cell Res Ther. 2016 Apr 19;7(1):59. doi: 10.1186/s13287-016-0311-6.

7.

A complex interplay between PGC-1 co-activators and mTORC1 regulates hematopoietic recovery following 5-fluorouracil treatment.

Basu S.

Stem Cell Res. 2014 Jan;12(1):178-93. doi: 10.1016/j.scr.2013.10.006. Epub 2013 Oct 24.

8.

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109. Epub 2012 May 18.

9.

Mice lack of LRG-47 display the attenuated outcome of infection with Schistosoma japonicum.

Gao Y, Wu J, Zhang M, Hou M, Ji M.

Parasitol Res. 2016 Mar;115(3):1185-93. doi: 10.1007/s00436-015-4853-9. Epub 2015 Dec 10.

PMID:
26660918
10.

Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.

Carnevalli LS, Scognamiglio R, Cabezas-Wallscheid N, Rahmig S, Laurenti E, Masuda K, Jöckel L, Kuck A, Sujer S, Polykratis A, Erlacher M, Pasparakis M, Essers MA, Trumpp A.

J Exp Med. 2014 May 5;211(5):769-79. doi: 10.1084/jem.20131072. Epub 2014 Apr 21.

11.

Adiponectin Enhances Quiescence Exit of Murine Hematopoietic Stem Cells and Hematopoietic Recovery Through mTORC1 Potentiation.

Masamoto Y, Arai S, Sato T, Kubota N, Takamoto I, Kadowaki T, Kurokawa M.

Stem Cells. 2017 Jul;35(7):1835-1848. doi: 10.1002/stem.2640. Epub 2017 May 23.

12.

Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection.

Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA.

Nature. 2010 Jun 10;465(7299):793-7. doi: 10.1038/nature09135.

13.

Fak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic stem cell expansion.

Lu J, Sun Y, Nombela-Arrieta C, Du KP, Park SY, Chai L, Walkley C, Luo HR, Silberstein LE.

Exp Hematol. 2012 Apr;40(4):307-17.e3. doi: 10.1016/j.exphem.2011.11.010. Epub 2011 Dec 8.

14.

Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.

Springer HM, Schramm M, Taylor GA, Howard JC.

J Immunol. 2013 Aug 15;191(4):1765-74. doi: 10.4049/jimmunol.1300641. Epub 2013 Jul 10.

15.

Dock2 participates in bone marrow lympho-hematopoiesis.

Kikuchi T, Kubonishi S, Shibakura M, Namba N, Matsui T, Fukui Y, Tanimoto M, Katayama Y.

Biochem Biophys Res Commun. 2008 Feb 29;367(1):90-6. Epub 2007 Dec 26.

PMID:
18157938
16.

Endothelial Cell-Selective Adhesion Molecule Expression in Hematopoietic Stem/Progenitor Cells Is Essential for Erythropoiesis Recovery after Bone Marrow Injury.

Sudo T, Yokota T, Okuzaki D, Ueda T, Ichii M, Ishibashi T, Isono T, Habuchi Y, Oritani K, Kanakura Y.

PLoS One. 2016 Apr 25;11(4):e0154189. doi: 10.1371/journal.pone.0154189. eCollection 2016.

17.

Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence.

Luo Y, Li L, Zou P, Wang J, Shao L, Zhou D, Liu L.

Transplantation. 2014 Jan 15;97(1):20-9. doi: 10.1097/TP.0b013e3182a7fcf8.

18.

Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential.

Xu H, Eleswarapu S, Geiger H, Szczur K, Daria D, Zheng Y, Settleman J, Srour EF, Williams DA, Filippi MD.

Blood. 2009 Oct 22;114(17):3557-66. doi: 10.1182/blood-2009-02-205815. Epub 2009 Aug 27.

19.

Robo4 plays a role in bone marrow homing and mobilization, but is not essential in the long-term repopulating capacity of hematopoietic stem cells.

Goto-Koshino Y, Fukuchi Y, Shibata F, Abe D, Kuroda K, Okamoto S, Kitamura T, Nakajima H.

PLoS One. 2012;7(11):e50849. doi: 10.1371/journal.pone.0050849. Epub 2012 Nov 30.

20.

Frizzled-6 Regulates Hematopoietic Stem/Progenitor Cell Survival and Self-Renewal.

Abidin BM, Owusu Kwarteng E, Heinonen KM.

J Immunol. 2015 Sep 1;195(5):2168-76. doi: 10.4049/jimmunol.1403213. Epub 2015 Jul 17.

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