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Items: 1 to 20 of 391

1.

Integrin connections to the cytoskeleton through talin and vinculin.

Ziegler WH, Gingras AR, Critchley DR, Emsley J.

Biochem Soc Trans. 2008 Apr;36(Pt 2):235-9. doi: 10.1042/BST0360235. Review.

PMID:
18363566
2.

A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

Fillingham I, Gingras AR, Papagrigoriou E, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL.

Structure. 2005 Jan;13(1):65-74.

3.

The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin.

Bois PR, O'Hara BP, Nietlispach D, Kirkpatrick J, Izard T.

J Biol Chem. 2006 Mar 17;281(11):7228-36. Epub 2006 Jan 9.

4.

Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.

Yogesha SD, Rangarajan ES, Vonrhein C, Bricogne G, Izard T.

Protein Sci. 2012 Apr;21(4):583-8. doi: 10.1002/pro.2041. Epub 2012 Feb 28.

5.

Structural and dynamic characterization of a vinculin binding site in the talin rod.

Gingras AR, Vogel KP, Steinhoff HJ, Ziegler WH, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL.

Biochemistry. 2006 Feb 14;45(6):1805-17.

PMID:
16460027
6.

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

Gingras AR, Ziegler WH, Frank R, Barsukov IL, Roberts GC, Critchley DR, Emsley J.

J Biol Chem. 2005 Nov 4;280(44):37217-24. Epub 2005 Aug 30.

7.

A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain.

Tremuth L, Kreis S, Melchior C, Hoebeke J, Rondé P, Plançon S, Takeda K, Kieffer N.

J Biol Chem. 2004 May 21;279(21):22258-66. Epub 2004 Mar 18.

8.

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.

Critchley DR.

Biochem Soc Trans. 2004 Nov;32(Pt 5):831-6. Review.

PMID:
15494027
9.

Integrin-mediated cell adhesion: the cytoskeletal connection.

Critchley DR, Holt MR, Barry ST, Priddle H, Hemmings L, Norman J.

Biochem Soc Symp. 1999;65:79-99. Review.

PMID:
10320934
10.

Crystal structure of the talin integrin binding domain 2.

Cheung TY, Fairchild MJ, Zarivach R, Tanentzapf G, Van Petegem F.

J Mol Biol. 2009 Apr 10;387(4):787-93.

PMID:
19340939
11.

The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod.

Patel B, Gingras AR, Bobkov AA, Fujimoto LM, Zhang M, Liddington RC, Mazzeo D, Emsley J, Roberts GC, Barsukov IL, Critchley DR.

J Biol Chem. 2006 Mar 17;281(11):7458-67. Epub 2006 Jan 9.

12.

Vinculin activation by talin through helical bundle conversion.

Izard T, Evans G, Borgon RA, Rush CL, Bricogne G, Bois PR.

Nature. 2004 Jan 8;427(6970):171-5. Epub 2003 Dec 31.

PMID:
14702644
13.

Structural basis for amplifying vinculin activation by talin.

Izard T, Vonrhein C.

J Biol Chem. 2004 Jun 25;279(26):27667-78. Epub 2004 Apr 7.

14.

Talin controls integrin activation.

Calderwood DA.

Biochem Soc Trans. 2004 Jun;32(Pt3):434-7. Review.

PMID:
15157154
15.

Coincidence of actin filaments and talin is required to activate vinculin.

Chen H, Choudhury DM, Craig SW.

J Biol Chem. 2006 Dec 29;281(52):40389-98. Epub 2006 Oct 29.

16.

The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.

Moes M, Rodius S, Coleman SJ, Monkley SJ, Goormaghtigh E, Tremuth L, Kox C, van der Holst PP, Critchley DR, Kieffer N.

J Biol Chem. 2007 Jun 8;282(23):17280-8. Epub 2007 Apr 11.

17.

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle.

Papagrigoriou E, Gingras AR, Barsukov IL, Bate N, Fillingham IJ, Patel B, Frank R, Ziegler WH, Roberts GC, Critchley DR, Emsley J.

EMBO J. 2004 Aug 4;23(15):2942-51. Epub 2004 Jul 22.

18.

Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.

Yogesha SD, Sharff A, Bricogne G, Izard T.

Protein Sci. 2011 Aug;20(8):1471-6. doi: 10.1002/pro.671.

19.

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation.

Calderwood DA, Zent R, Grant R, Rees DJ, Hynes RO, Ginsberg MH.

J Biol Chem. 1999 Oct 1;274(40):28071-4.

20.

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