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Items: 1 to 20 of 84

1.

Characterization of chemical libraries for luciferase inhibitory activity.

Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J.

J Med Chem. 2008 Apr 24;51(8):2372-86. doi: 10.1021/jm701302v. Epub 2008 Mar 26.

PMID:
18363348
2.

Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays.

Ho PI, Yue K, Pandey P, Breault L, Harbinski F, McBride AJ, Webb B, Narahari J, Karassina N, Wood KV, Hill A, Auld DS.

ACS Chem Biol. 2013 May 17;8(5):1009-17. doi: 10.1021/cb3007264. Epub 2013 Mar 26.

PMID:
23485150
3.

Discovery of 5-benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-benzyl-3-phenyl-1,4,2-dioxazoles as potent firefly luciferase inhibitors.

Poutiainen PK, Palvimo JJ, Hinkkanen AE, Valkonen A, Väisänen TK, Laatikainen R, Pulkkinen JT.

J Med Chem. 2013 Feb 14;56(3):1064-73. doi: 10.1021/jm301516q. Epub 2013 Jan 17.

PMID:
23286196
4.

A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution.

Auld DS, Zhang YQ, Southall NT, Rai G, Landsman M, MacLure J, Langevin D, Thomas CJ, Austin CP, Inglese J.

J Med Chem. 2009 Mar 12;52(5):1450-8. doi: 10.1021/jm8014525.

5.

Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays.

Dranchak P, MacArthur R, Guha R, Zuercher WJ, Drewry DH, Auld DS, Inglese J.

PLoS One. 2013;8(3):e57888. doi: 10.1371/journal.pone.0057888. Epub 2013 Mar 7.

6.
7.

Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression.

Auld DS, Thorne N, Maguire WF, Inglese J.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3585-90. doi: 10.1073/pnas.0813345106. Epub 2009 Feb 10.

8.

Spectroscopic and functional characterization of Lampyris turkestanicus luciferase: a comparative study.

Mortazavi M, Hosseinkhani S, Khajeh K, Ranjbar B, Emamzadeh AR.

Acta Biochim Biophys Sin (Shanghai). 2008 May;40(5):365-74.

9.

A specific mechanism for nonspecific activation in reporter-gene assays.

Auld DS, Thorne N, Nguyen DT, Inglese J.

ACS Chem Biol. 2008 Aug 15;3(8):463-70. doi: 10.1021/cb8000793. Epub 2008 Jul 1.

10.

A real-time bioluminescent HTS method for measuring protein kinase activity influenced neither by ATP concentration nor by luciferase inhibition.

Lundin A, Eriksson J.

Assay Drug Dev Technol. 2008 Aug;6(4):531-41. doi: 10.1089/adt.2008.133.

PMID:
18532902
11.

The nuclear factor κB inhibitor (E)-2-fluoro-4'-methoxystilbene inhibits firefly luciferase.

Braeuning A, Vetter S.

Biosci Rep. 2012 Dec;32(6):531-7. doi: 10.1042/BSR20120043.

12.

A Photinus pyralis and Luciola italica chimeric firefly luciferase produces enhanced bioluminescence.

Branchini BR, Southworth TL, Fontaine DM, Davis AL, Behney CE, Murtiashaw MH.

Biochemistry. 2014 Oct 14;53(40):6287-9. doi: 10.1021/bi501202u. Epub 2014 Oct 1.

PMID:
25264115
13.

Structural basis for the spectral difference in luciferase bioluminescence.

Nakatsu T, Ichiyama S, Hiratake J, Saldanha A, Kobashi N, Sakata K, Kato H.

Nature. 2006 Mar 16;440(7082):372-6.

PMID:
16541080
14.

Luciferase inhibition by a novel naphthoquinone.

Bedford R, LePage D, Hoffmann R, Kennedy S, Gutschenritter T, Bull L, Sujijantarat N, DiCesare JC, Sheaff RJ.

J Photochem Photobiol B. 2012 Feb 6;107:55-64. doi: 10.1016/j.jphotobiol.2011.11.008. Epub 2011 Dec 8.

PMID:
22197716
15.

A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays.

Hampf M, Gossen M.

Anal Biochem. 2006 Sep 1;356(1):94-9. Epub 2006 May 12.

PMID:
16750160
16.

Pyrrolo[2,3-b]quinoxalines as inhibitors of firefly luciferase: their Cu-mediated synthesis and evaluation as false positives in a reporter gene assay.

Nakhi A, Rahman MS, Kishore R, Meda CL, Deora GS, Parsa KV, Pal M.

Bioorg Med Chem Lett. 2012 Oct 15;22(20):6433-41. doi: 10.1016/j.bmcl.2012.08.056. Epub 2012 Aug 22.

PMID:
22981335
17.

Structural evolution of luciferase activity in Zophobas mealworm AMP/CoA-ligase (protoluciferase) through site-directed mutagenesis of the luciferin binding site.

Prado RA, Barbosa JA, Ohmiya Y, Viviani VR.

Photochem Photobiol Sci. 2011 Jul;10(7):1226-32. doi: 10.1039/c0pp00392a. Epub 2011 Apr 19.

PMID:
21505686
18.

Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitors.

Liu Y, Fang J, Cai H, Xiao F, Ding K, Hu Y.

Bioorg Med Chem. 2012 Sep 15;20(18):5473-82. doi: 10.1016/j.bmc.2012.07.035. Epub 2012 Jul 28.

PMID:
22898255
19.

TD-DFT/molecular mechanics study of the Photinus pyralis bioluminescence system.

Pinto da Silva L, Esteves da Silva JC.

J Phys Chem B. 2012 Feb 16;116(6):2008-13. doi: 10.1021/jp2120059. Epub 2012 Feb 6.

PMID:
22243426
20.

A new firefly luciferase with bimodal spectrum: identification of structural determinants of spectral pH-sensitivity in firefly luciferases.

Viviani VR, Oehlmeyer TL, Arnoldi FG, Brochetto-Braga MR.

Photochem Photobiol. 2005 Jul-Aug;81(4):843-8.

PMID:
16124832

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