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Items: 1 to 20 of 88

1.

HOXB4 and retroviral vectors: adding fuel to the fire.

Larochelle A, Dunbar CE.

J Clin Invest. 2008 Apr;118(4):1350-3. doi: 10.1172/JCI35326.

2.

In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein.

Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G.

Nat Med. 2003 Nov;9(11):1428-32. Epub 2003 Oct 26.

PMID:
14578881
3.

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.

Zhang XB, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries RK, Kiem HP.

J Clin Invest. 2008 Apr;118(4):1502-10. doi: 10.1172/JCI34371.

4.
5.

Effects of HOXB4 overexpression on ex vivo expansion and immortalization of hematopoietic cells from different species.

Zhang XB, Schwartz JL, Humphries RK, Kiem HP.

Stem Cells. 2007 Aug;25(8):2074-81. Epub 2007 May 17.

6.

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation.

Schiedlmeier B, Klump H, Will E, Arman-Kalcek G, Li Z, Wang Z, Rimek A, Friel J, Baum C, Ostertag W.

Blood. 2003 Mar 1;101(5):1759-68. Epub 2002 Oct 24.

7.

Lentiviral-mediated HoxB4 expression in human embryonic stem cells initiates early hematopoiesis in a dose-dependent manner but does not promote myeloid differentiation.

Unger C, Kärner E, Treschow A, Stellan B, Felldin U, Concha H, Wendel M, Hovatta O, Aints A, Ahrlund-Richter L, Dilber MS.

Stem Cells. 2008 Oct;26(10):2455-66. doi: 10.1634/stemcells.2007-0876. Epub 2008 Jul 10.

8.

HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation.

Antonchuk J, Sauvageau G, Humphries RK.

Exp Hematol. 2001 Sep;29(9):1125-34.

PMID:
11532354
9.

Development of hematopoietic stem and progenitor cells from mouse embryonic stem cells, in vitro, supported by ectopic human HOXB4 expression.

Pilat S, Carotta S, Klump H.

Methods Mol Biol. 2013;1029:129-47. doi: 10.1007/978-1-62703-478-4_10.

PMID:
23756947
10.

Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O6-methylguanine-DNA-methyltransferase and HOXB4.

Milsom MD, Woolford LB, Margison GP, Humphries RK, Fairbairn LJ.

Mol Ther. 2004 Nov;10(5):862-73. Erratum in: Mol Ther. 2005 Oct;12(4):772-3.

11.
12.

Studies on HOXB4 expression during differentiation of human cytomegalovirus-infected hematopoietic stem cells into lymphocyte and erythrocyte progenitor cells.

Wen-jun L, qu-lian G, Hong-ying C, Yan Z, Mei-Xian H.

Cell Biochem Biophys. 2012 Jun;63(2):133-41. doi: 10.1007/s12013-012-9349-y.

PMID:
22402911
13.

Ex vivo expansion of human HSCs with Sendai virus vector expressing HoxB4 assessed by sheep in utero transplantation.

Abe T, Masuda S, Ban H, Hayashi S, Ueda Y, Inoue M, Hasegawa M, Nagao Y, Hanazono Y.

Exp Hematol. 2011 Jan;39(1):47-54. doi: 10.1016/j.exphem.2010.09.007. Epub 2010 Sep 26.

PMID:
20875838
14.

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells.

Buske C, Feuring-Buske M, Abramovich C, Spiekermann K, Eaves CJ, Coulombel L, Sauvageau G, Hogge DE, Humphries RK.

Blood. 2002 Aug 1;100(3):862-8.

16.

Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells.

Lee HM, Zhang H, Schulz V, Tuck DP, Forget BG.

Blood. 2010 Aug 5;116(5):720-30. doi: 10.1182/blood-2009-11-253872. Epub 2010 Apr 19.

17.

[Ex vivo expansion of human hematopoietic stem cells by passive transduction of the HOXB4 homeoprotein].

Amsellem S, Fichelson S.

J Soc Biol. 2006;200(3):235-41. Review. French.

PMID:
17417138
18.

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.

Pilat S, Carotta S, Schiedlmeier B, Kamino K, Mairhofer A, Will E, Modlich U, Steinlein P, Ostertag W, Baum C, Beug H, Klump H.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12101-6. Epub 2005 Aug 10.

19.

Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy.

Klump H, Schiedlmeier B, Vogt B, Ryan M, Ostertag W, Baum C.

Gene Ther. 2001 May;8(10):811-7.

20.

HOXB4 inhibits cell growth in a dose-dependent manner and sensitizes cells towards extrinsic cues.

Will E, Speidel D, Wang Z, Ghiaur G, Rimek A, Schiedlmeier B, Williams DA, Baum C, Ostertag W, Klump H.

Cell Cycle. 2006 Jan;5(1):14-22. Epub 2006 Jan 9.

PMID:
16357528

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