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Items: 1 to 20 of 243


Suppression of the Raf/MEK/ERK signaling cascade and inhibition of angiogenesis by the carboxyl terminus of angiopoietin-like protein 4.

Yang YH, Wang Y, Lam KS, Yau MH, Cheng KK, Zhang J, Zhu W, Wu D, Xu A.

Arterioscler Thromb Vasc Biol. 2008 May;28(5):835-40. doi: 10.1161/ATVBAHA.107.157776. Epub 2008 Mar 13.


Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, Wilhelm S, Lynch M, Carter C.

Cancer Res. 2006 Dec 15;66(24):11851-8.


Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways.

Lee SJ, Namkoong S, Kim YM, Kim CK, Lee H, Ha KS, Chung HT, Kwon YG, Kim YM.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2836-46. Epub 2006 Jul 28.


Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4.

Ge H, Yang G, Huang L, Motola DL, Pourbahrami T, Li C.

J Biol Chem. 2004 Jan 16;279(3):2038-45. Epub 2003 Oct 21.


Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes.

Lang SA, Schachtschneider P, Moser C, Mori A, Hackl C, Gaumann A, Batt D, Schlitt HJ, Geissler EK, Stoeltzing O.

Mol Cancer Ther. 2008 Nov;7(11):3509-18. doi: 10.1158/1535-7163.MCT-08-0373.


Hypoxia-induced mitogenic factor enhances angiogenesis by promoting proliferation and migration of endothelial cells.

Tong Q, Zheng L, Li B, Wang D, Huang C, Matuschak GM, Li D.

Exp Cell Res. 2006 Nov 1;312(18):3559-69. Epub 2006 Aug 9.


Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling.

Namkoong S, Kim CK, Cho YL, Kim JH, Lee H, Ha KS, Choe J, Kim PH, Won MH, Kwon YG, Shim EB, Kim YM.

Cell Signal. 2009 Jun;21(6):906-15.


Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.

Roberts PJ, Der CJ.

Oncogene. 2007 May 14;26(22):3291-310. Review.


Insulin-like growth factor binding protein-7 (IGFBP7) blocks vascular endothelial cell growth factor (VEGF)-induced angiogenesis in human vascular endothelial cells.

Tamura K, Hashimoto K, Suzuki K, Yoshie M, Kutsukake M, Sakurai T.

Eur J Pharmacol. 2009 May 21;610(1-3):61-7. doi: 10.1016/j.ejphar.2009.01.045. Epub 2009 Feb 5.


Semaphorin-3F is an inhibitor of tumor angiogenesis.

Kessler O, Shraga-Heled N, Lange T, Gutmann-Raviv N, Sabo E, Baruch L, Machluf M, Neufeld G.

Cancer Res. 2004 Feb 1;64(3):1008-15.


Differential effect of FGF and PDGF on cell proliferation and migration in osteoblastic cells.

Kim SJ, Kim SY, Kwon CH, Kim YK.

Growth Factors. 2007 Apr;25(2):77-86.


Visfatin activates eNOS via Akt and MAP kinases and improves endothelial cell function and angiogenesis in vitro and in vivo: translational implications for atherosclerosis.

Lovren F, Pan Y, Shukla PC, Quan A, Teoh H, Szmitko PE, Peterson MD, Gupta M, Al-Omran M, Verma S.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1440-9. doi: 10.1152/ajpendo.90780.2008. Epub 2009 Apr 7.


ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo.

Camenisch G, Pisabarro MT, Sherman D, Kowalski J, Nagel M, Hass P, Xie MH, Gurney A, Bodary S, Liang XH, Clark K, Beresini M, Ferrara N, Gerber HP.

J Biol Chem. 2002 May 10;277(19):17281-90. Epub 2002 Feb 27.


Na+/K+/Cl- cotransporter activates MAP-kinase cascade downstream to protein kinase C, and upstream to MEK.

Panet R, Eliash M, Atlan H.

J Cell Physiol. 2006 Mar;206(3):578-85.


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