Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 101

1.

Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc.

Ju T, Lanneau GS, Gautam T, Wang Y, Xia B, Stowell SR, Willard MT, Wang W, Xia JY, Zuna RE, Laszik Z, Benbrook DM, Hanigan MH, Cummings RD.

Cancer Res. 2008 Mar 15;68(6):1636-46. doi: 10.1158/0008-5472.CAN-07-2345. Erratum in: Cancer Res. 2008 Apr 15;68(8):3076.

2.

Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.

Yu X, Du Z, Sun X, Shi C, Zhang H, Hu T.

Int J Clin Exp Pathol. 2015 Mar 1;8(3):2590-602. eCollection 2015.

3.

The Cosmc connection to the Tn antigen in cancer.

Ju T, Aryal RP, Kudelka MR, Wang Y, Cummings RD.

Cancer Biomark. 2014 Jan 1;14(1):63-81. doi: 10.3233/CBM-130375. Review.

PMID:
24643043
4.

COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.

Hofmann BT, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak AS, Harder S, El Gammal AT, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki JR, Jücker M, Bockhorn M, Wolters-Eisfeld G.

Mol Cancer. 2015 May 29;14:109. doi: 10.1186/s12943-015-0386-1.

5.

Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen.

Mi R, Song L, Wang Y, Ding X, Zeng J, Lehoux S, Aryal RP, Wang J, Crew VK, van Die I, Chapman AB, Cummings RD, Ju T.

J Biol Chem. 2012 Nov 30;287(49):41523-33. doi: 10.1074/jbc.M112.371989. Epub 2012 Oct 3. Erratum in: J Biol Chem. 2013 Apr 19;288(16):11505.

6.

New mutations in C1GALT1C1 in individuals with Tn positive phenotype.

Crew VK, Singleton BK, Green C, Parsons SF, Daniels G, Anstee DJ.

Br J Haematol. 2008 Aug;142(4):657-67. doi: 10.1111/j.1365-2141.2008.07215.x. Epub 2008 Jun 5.

PMID:
18537974
7.

Cosmc is an essential chaperone for correct protein O-glycosylation.

Wang Y, Ju T, Ding X, Xia B, Wang W, Xia L, He M, Cummings RD.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9228-33. doi: 10.1073/pnas.0914004107. Epub 2010 May 3.

8.

Functional assays for the molecular chaperone cosmc.

Ju T, Cummings RD.

Methods Enzymol. 2010;479:107-22. doi: 10.1016/S0076-6879(10)79006-6.

PMID:
20816162
9.

The Role of Sialyl-Tn in Cancer.

Munkley J.

Int J Mol Sci. 2016 Feb 24;17(3):275. doi: 10.3390/ijms17030275. Review.

10.

Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers.

Ju T, Wang Y, Aryal RP, Lehoux SD, Ding X, Kudelka MR, Cutler C, Zeng J, Wang J, Sun X, Heimburg-Molinaro J, Smith DF, Cummings RD.

Proteomics Clin Appl. 2013 Oct;7(9-10):618-31. doi: 10.1002/prca.201300024. Epub 2013 Sep 9. Review.

PMID:
23857728
11.

The Tn antigen-structural simplicity and biological complexity.

Ju T, Otto VI, Cummings RD.

Angew Chem Int Ed Engl. 2011 Feb 18;50(8):1770-91. doi: 10.1002/anie.201002313. Epub 2011 Jan 21. Review.

PMID:
21259410
12.

Protein glycosylation: chaperone mutation in Tn syndrome.

Ju T, Cummings RD.

Nature. 2005 Oct 27;437(7063):1252.

PMID:
16251947
13.

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

Beatson R, Maurstad G, Picco G, Arulappu A, Coleman J, Wandell HH, Clausen H, Mandel U, Taylor-Papadimitriou J, Sletmoen M, Burchell JM.

PLoS One. 2015 May 7;10(5):e0125994. doi: 10.1371/journal.pone.0125994. eCollection 2015.

14.

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.

Ju T, Cummings RD.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16613-8. Epub 2002 Dec 3.

16.
17.

Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.

Ikehara Y, Kojima N, Kurosawa N, Kudo T, Kono M, Nishihara S, Issiki S, Morozumi K, Itzkowitz S, Tsuda T, Nishimura SI, Tsuji S, Narimatsu H.

Glycobiology. 1999 Nov;9(11):1213-24.

PMID:
10536037
18.

Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen.

Marcos NT, Pinho S, Grandela C, Cruz A, Samyn-Petit B, Harduin-Lepers A, Almeida R, Silva F, Morais V, Costa J, Kihlberg J, Clausen H, Reis CA.

Cancer Res. 2004 Oct 1;64(19):7050-7.

19.
20.

Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing.

Madsen CB, Lavrsen K, Steentoft C, Vester-Christensen MB, Clausen H, Wandall HH, Pedersen AE.

PLoS One. 2013 Sep 6;8(9):e72413. doi: 10.1371/journal.pone.0072413. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/81b54c99-e47f-4128-8aeb-b6b3e8c02562.

Supplemental Content

Support Center