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Items: 1 to 20 of 98

1.

Response of human renal tubular cells to cyclosporine and sirolimus: a toxicogenomic study.

Pallet N, Rabant M, Xu-Dubois YC, Lecorre D, Mucchielli MH, Imbeaud S, Agier N, Hertig A, Thervet E, Legendre C, Beaune P, Anglicheau D.

Toxicol Appl Pharmacol. 2008 Jun 1;229(2):184-96. doi: 10.1016/j.taap.2008.01.019. Epub 2008 Feb 1.

PMID:
18331748
2.

Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats.

Lloberas N, Torras J, Alperovich G, Cruzado JM, Giménez-Bonafé P, Herrero-Fresneda I, Franquesa Ml, Rama I, Grinyó JM.

Nephrol Dial Transplant. 2008 Oct;23(10):3111-9. doi: 10.1093/ndt/gfn223. Epub 2008 May 9.

3.

Sirolimus and cyclosporine A alter barrier function in renal proximal tubular cells through stimulation of ERK1/2 signaling and claudin-1 expression.

Martin-Martin N, Ryan G, McMorrow T, Ryan MP.

Am J Physiol Renal Physiol. 2010 Mar;298(3):F672-82. doi: 10.1152/ajprenal.00199.2009. Epub 2009 Dec 2.

4.

RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells.

Martin-Martin N, Dan Q, Amoozadeh Y, Waheed F, McMorrow T, Ryan MP, Szászi K.

Int J Biochem Cell Biol. 2012 Jan;44(1):178-88. doi: 10.1016/j.biocel.2011.10.014. Epub 2011 Nov 2.

PMID:
22062948
5.

Preclinical results of sirolimus treatment in transplant models.

Stepkowski SM.

Transplant Proc. 2003 May;35(3 Suppl):219S-226S. Review.

PMID:
12742499
6.
7.

Autophagy protects renal tubular cells against cyclosporine toxicity.

Pallet N, Bouvier N, Legendre C, Gilleron J, Codogno P, Beaune P, Thervet E, Anglicheau D.

Autophagy. 2008 Aug;4(6):783-91. Epub 2008 Jun 20.

PMID:
18628650
8.

Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion.

Jennings P, Aydin S, Bennett J, McBride R, Weiland C, Tuite N, Gruber LN, Perco P, Gaora PO, Ellinger-Ziegelbauer H, Ahr HJ, Kooten CV, Daha MR, Prieto P, Ryan MP, Pfaller W, McMorrow T.

Toxicol In Vitro. 2009 Apr;23(3):486-99. doi: 10.1016/j.tiv.2008.12.023. Epub 2008 Dec 31.

PMID:
19159671
9.

Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.

Bohra R, Schöning W, Klawitter J, Brunner N, Schmitz V, Shokati T, Lawrence R, Arbelaez MF, Schniedewind B, Christians U, Klawitter J.

PLoS One. 2012;7(10):e48063. doi: 10.1371/journal.pone.0048063. Epub 2012 Oct 31.

10.

Effect of sirolimus on calcineurin inhibitor-induced nephrotoxicity using renal expression of KLOTHO, an antiaging gene.

Han DH, Piao SG, Song JH, Ghee JY, Hwang HS, Choi BS, Kim J, Yang CW.

Transplantation. 2010 Jul 27;90(2):135-41. doi: 10.1097/TP.0b013e3181e117b4.

PMID:
20562737
11.

Comparison of sirolimus plus tacrolimus versus sirolimus plus cyclosporine in high-risk renal allograft recipients: results from an open-label, randomized trial.

Gaber AO, Kahan BD, Van Buren C, Schulman SL, Scarola J, Neylan JF; Sirolimus High-Risk Study Group.

Transplantation. 2008 Nov 15;86(9):1187-95. doi: 10.1097/TP.0b013e318187bab0.

PMID:
19005398
12.

Human allograft arterial injury is ameliorated by sirolimus and cyclosporine and correlates with suppression of interferon-gamma.

Yi T, Cuchara L, Wang Y, Koh KP, Ranjbaran H, Tellides G, Pober JS, Lorber MI.

Transplantation. 2006 Feb 27;81(4):559-66.

PMID:
16495804
13.

Modeling individual variation in biomarker response to combination immunosuppression with stimulated lymphocyte responses-potential clinical implications.

Sindhi R, Allaert J, Gladding D, Haaland P, Koppelman B, Dunne J, Sehgal S.

J Immunol Methods. 2003 Jan 15;272(1-2):257-72.

PMID:
12505729
14.

Synergistic effects of sirolimus with cyclosporine and tacrolimus: analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood.

Barten MJ, Streit F, Boeger M, Dhein S, Tarnok A, Shipkova M, Armstrong VW, Mohr FW, Oellerich M, Gummert JF.

Transplantation. 2004 Apr 27;77(8):1154-62. Erratum in: Transplantation. 2005 Jun 27;79(12):1773.

PMID:
15114077
15.

Hypertension induced by immunosuppressive drugs: a comparative analysis between sirolimus and cyclosporine.

Reis F, Parada B, Teixeira de Lemos E, Garrido P, Dias A, Piloto N, Baptista S, Sereno J, Eufrásio P, Costa E, Rocha-Pereira P, Santos-Silva A, Figueiredo A, Mota A, Teixeira F.

Transplant Proc. 2009 Apr;41(3):868-73. doi: 10.1016/j.transproceed.2009.02.005.

PMID:
19376375
16.

Metabolic interaction between cyclosporine and sirolimus.

Bai S, Stepkowski SM, Kahan BD, Brunner LJ.

Transplantation. 2004 May 27;77(10):1507-12.

PMID:
15239612
17.

Impact of reduced nephron mass on cyclosporine- and/or sirolimus-induced nephrotoxicity.

Fernandes I, Zhang Y, Qi Y, Wang ME, Podder H, Lisik W, Knight R, Kahan BD, Stepkowski SM.

Transplantation. 2009 Dec 27;88(12):1323-31. doi: 10.1097/TP.0b013e3181bd5951.

PMID:
20029328
18.

Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells.

O'Connell S, Slattery C, Ryan MP, McMorrow T.

J Transplant. 2012;2012:980910. doi: 10.1155/2012/980910. Epub 2012 Jan 23.

19.

Cyclosporine-induced tubular vacuolization: the role of Bip/Grp78.

Cheng CH, Shu KH, Chang HR, Chou MC.

Nephron Exp Nephrol. 2012;122(1-2):1-12. doi: 10.1159/000346956. Epub 2013 Feb 15.

PMID:
23428559
20.

The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery.

Hsu HJ, Tian YC, Chen YC, Lai BC, Fang JT, Yang CW, Wu MS.

Ren Fail. 2008;30(3):303-6. doi: 10.1080/08860220701860989.

PMID:
18350450
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