Similar articles for PMID: 18323781

Year	Number of Results
1999	1
2000	3
2001	1
2002	5
2003	2
2004	2
2005	5
2006	9
2007	10
2008	12
2009	26
2010	33
2011	25
2012	36
2013	20
2014	18
2015	8
2016	8
2017	10
2018	12
2019	9
2020	15
2021	11
2022	7
2023	2
2024	0

1

Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.

Lasithiotakis KG, Sinnberg TW, Schittek B, Flaherty KT, Kulms D, Maczey E, Garbe C, Meier FE. Lasithiotakis KG, et al. J Invest Dermatol. 2008 Aug;128(8):2013-23. doi: 10.1038/jid.2008.44. Epub 2008 Mar 6. J Invest Dermatol. 2008. PMID: 18323781 Free article.

2

The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells.

Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F. Niessner H, et al. J Invest Dermatol. 2011 Feb;131(2):468-79. doi: 10.1038/jid.2010.297. Epub 2010 Oct 14. J Invest Dermatol. 2011. PMID: 20944654 Free article.

3

PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.

Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Evers BM. Gedaly R, et al. J Surg Res. 2012 Aug;176(2):542-8. doi: 10.1016/j.jss.2011.10.045. Epub 2011 Nov 21. J Surg Res. 2012. PMID: 22261591

4

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells.

Pal HC, Baxter RD, Hunt KM, Agarwal J, Elmets CA, Athar M, Afaq F. Pal HC, et al. Oncotarget. 2015 Sep 29;6(29):28296-311. doi: 10.18632/oncotarget.5064. Oncotarget. 2015. PMID: 26299806 Free PMC article.

5

Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy.

Augustine CK, Toshimitsu H, Jung SH, Zipfel PA, Yoo JS, Yoshimoto Y, Selim MA, Burchette J, Beasley GM, McMahon N, Padussis J, Pruitt SK, Ali-Osman F, Tyler DS. Augustine CK, et al. Mol Cancer Ther. 2010 Jul;9(7):2090-101. doi: 10.1158/1535-7163.MCT-10-0073. Epub 2010 Jun 22. Mol Cancer Ther. 2010. PMID: 20571072

6

PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways.

Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Koch A, Evers BM. Gedaly R, et al. Anticancer Res. 2010 Dec;30(12):4951-8. Anticancer Res. 2010. PMID: 21187475 Free PMC article.

7

Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.

Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W. Ulivi P, et al. J Cell Physiol. 2009 Jul;220(1):214-21. doi: 10.1002/jcp.21753. J Cell Physiol. 2009. PMID: 19288493

8

Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype.

Ho AL, Musi E, Ambrosini G, Nair JS, Deraje Vasudeva S, de Stanchina E, Schwartz GK. Ho AL, et al. PLoS One. 2012;7(7):e40439. doi: 10.1371/journal.pone.0040439. Epub 2012 Jul 10. PLoS One. 2012. PMID: 22808163 Free PMC article.

9

Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.

Meier F, Busch S, Lasithiotakis K, Kulms D, Garbe C, Maczey E, Herlyn M, Schittek B. Meier F, et al. Br J Dermatol. 2007 Jun;156(6):1204-13. doi: 10.1111/j.1365-2133.2007.07821.x. Epub 2007 Mar 28. Br J Dermatol. 2007. PMID: 17388918

10

Sorafenib induces growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway.

Peng CL, Guo W, Ji T, Ren T, Yang Y, Li DS, Qu HY, Li X, Tang S, Yan TQ, Tang XD. Peng CL, et al. Cancer Biol Ther. 2009 Sep;8(18):1729-36. doi: 10.4161/cbt.8.18.9208. Epub 2009 Sep 6. Cancer Biol Ther. 2009. PMID: 19633425

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