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Anamnestic protective immunity to Bacillus anthracis is antibody mediated but independent of complement and Fc receptors.

Harvill ET, Osorio M, Loving CL, Lee GM, Kelly VK, Merkel TJ.

Infect Immun. 2008 May;76(5):2177-82. doi: 10.1128/IAI.00647-07. Epub 2008 Mar 3.


Significant passive protective effect against anthrax by antibody to Bacillus anthracis inactivated spores that lack two virulence plasmids.

Enkhtuya J, Kawamoto K, Kobayashi Y, Uchida I, Rana N, Makino S.

Microbiology. 2006 Oct;152(Pt 10):3103-10.


Passive transfer of protection against Bacillus anthracis infection in a murine model.

Beedham RJ, Turnbull PC, Williamson ED.

Vaccine. 2001 Aug 14;19(31):4409-16.


CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies.

Devera TS, Aye LM, Lang GA, Joshi SK, Ballard JD, Lang ML.

Infect Immun. 2010 Apr;78(4):1610-7. doi: 10.1128/IAI.00002-10. Epub 2010 Feb 1.


Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant.

Park YS, Lee JH, Hung CF, Wu TC, Kim TW.

Infect Immun. 2008 May;76(5):1952-9. doi: 10.1128/IAI.01722-07. Epub 2008 Feb 19.


Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax.

Albrecht MT, Li H, Williamson ED, LeButt CS, Flick-Smith HC, Quinn CP, Westra H, Galloway D, Mateczun A, Goldman S, Groen H, Baillie LW.

Infect Immun. 2007 Nov;75(11):5425-33. Epub 2007 Jul 23.


A plant based protective antigen [PA(dIV)] vaccine expressed in chloroplasts demonstrates protective immunity in mice against anthrax.

Gorantala J, Grover S, Goel D, Rahi A, Jayadev Magani SK, Chandra S, Bhatnagar R.

Vaccine. 2011 Jun 15;29(27):4521-33. doi: 10.1016/j.vaccine.2011.03.082. Epub 2011 Apr 17.


A combination of the TLR4 agonist CIA05 and alum promotes the immune responses to Bacillus anthracis protective antigen in mice.

Wui SR, Kim HK, Han JE, Kim JM, Kim YH, Chun JH, Cho YJ, Lee NG.

Int Immunopharmacol. 2011 Sep;11(9):1195-204. doi: 10.1016/j.intimp.2011.03.020. Epub 2011 Apr 12.


Role of anthrax toxins in dissemination, disease progression, and induction of protective adaptive immunity in the mouse aerosol challenge model.

Loving CL, Khurana T, Osorio M, Lee GM, Kelly VK, Stibitz S, Merkel TJ.

Infect Immun. 2009 Jan;77(1):255-65. doi: 10.1128/IAI.00633-08. Epub 2008 Oct 27.


A requirement for FcγR in antibody-mediated bacterial toxin neutralization.

Abboud N, Chow SK, Saylor C, Janda A, Ravetch JV, Scharff MD, Casadevall A.

J Exp Med. 2010 Oct 25;207(11):2395-405. doi: 10.1084/jem.20100995. Epub 2010 Oct 4.


Poly-gamma-d-glutamic acid and protective antigen conjugate vaccines induce functional antibodies against the protective antigen and capsule of Bacillus anthracis in guinea-pigs and rabbits.

Lee DY, Chun JH, Ha HJ, Park J, Kim BS, Oh HB, Rhie GE.

FEMS Immunol Med Microbiol. 2009 Nov;57(2):165-72. doi: 10.1111/j.1574-695X.2009.00595.x. Epub 2009 Aug 6.


Identification and characterization of immunodominant B-cell epitope of the C-terminus of protective antigen of Bacillus anthracis.

Kaur M, Chug H, Singh H, Chandra S, Mishra M, Sharma M, Bhatnagar R.

Mol Immunol. 2009 Jun;46(10):2107-15. doi: 10.1016/j.molimm.2008.12.031. Epub 2009 Apr 7.


Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax.

Skoble J, Beaber JW, Gao Y, Lovchik JA, Sower LE, Liu W, Luckett W, Peterson JW, Calendar R, Portnoy DA, Lyons CR, Dubensky TW Jr.

Infect Immun. 2009 Apr;77(4):1649-63. doi: 10.1128/IAI.00530-08. Epub 2009 Jan 21.


Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice.

Honda S, Kurita N, Miyamoto A, Cho Y, Usui K, Takeshita K, Takahashi S, Yasui T, Kikutani H, Kinoshita T, Fujita T, Tahara-Hanaoka S, Shibuya K, Shibuya A.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11230-5. doi: 10.1073/pnas.0809917106. Epub 2009 Jun 19.


Bacillus anthracis Capsular Conjugates Elicit Chimpanzee Polyclonal Antibodies That Protect Mice from Pulmonary Anthrax.

Chen Z, Schneerson R, Lovchik JA, Dai Z, Kubler-Kielb J, Agulto L, Leppla SH, Purcell RH.

Clin Vaccine Immunol. 2015 Aug;22(8):902-8. doi: 10.1128/CVI.00137-15. Epub 2015 Jun 3.


Protective immunity induced by Bacillus anthracis toxin-deficient strains.

Pezard C, Weber M, Sirard JC, Berche P, Mock M.

Infect Immun. 1995 Apr;63(4):1369-72.


Antibody-mediated immunity to the obligate intracellular bacterial pathogen Coxiella burnetii is Fc receptor- and complement-independent.

Shannon JG, Cockrell DC, Takahashi K, Stahl GL, Heinzen RA.

BMC Immunol. 2009 May 8;10:26. doi: 10.1186/1471-2172-10-26.


Recombinant Bacillus anthracis spore proteins enhance protection of mice primed with suboptimal amounts of protective antigen.

Cybulski RJ Jr, Sanz P, McDaniel D, Darnell S, Bull RL, O'Brien AD.

Vaccine. 2008 Sep 8;26(38):4927-39. doi: 10.1016/j.vaccine.2008.07.015. Epub 2008 Jul 25.

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