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Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.

Ripoll VM, Meadows NA, Raggatt LJ, Chang MK, Pettit AR, Cassady AI, Hume DA.

Gene. 2008 Apr 30;413(1-2):32-41. doi: 10.1016/j.gene.2008.01.014. Epub 2008 Jan 26.


The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor.

Meadows NA, Sharma SM, Faulkner GJ, Ostrowski MC, Hume DA, Cassady AI.

J Biol Chem. 2007 Jan 19;282(3):1891-904. Epub 2006 Nov 14.


The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts.

Luchin A, Purdom G, Murphy K, Clark MY, Angel N, Cassady AI, Hume DA, Ostrowski MC.

J Bone Miner Res. 2000 Mar;15(3):451-60.


The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).

Bronisz A, Carey HA, Godlewski J, Sif S, Ostrowski MC, Sharma SM.

J Biol Chem. 2014 Jan 3;289(1):326-34. doi: 10.1074/jbc.M113.493874. Epub 2013 Nov 20.


Gpnmb is a melanoblast-expressed, MITF-dependent gene.

Loftus SK, Antonellis A, Matera I, Renaud G, Baxter LL, Reid D, Wolfsberg TG, Chen Y, Wang C; NISC Comparative Sequencing Program., Prasad MK, Bessling SL, McCallion AS, Green ED, Bennett DC, Pavan WJ.

Pigment Cell Melanoma Res. 2009 Feb;22(1):99-110. doi: 10.1111/j.1755-148X.2008.00518.x. Epub 2008 Nov 1.


Myocyte enhancer factor 2 and microphthalmia-associated transcription factor cooperate with NFATc1 to transactivate the V-ATPase d2 promoter during RANKL-induced osteoclastogenesis.

Feng H, Cheng T, Steer JH, Joyce DA, Pavlos NJ, Leong C, Kular J, Liu J, Feng X, Zheng MH, Xu J.

J Biol Chem. 2009 May 22;284(21):14667-76. doi: 10.1074/jbc.M901670200. Epub 2009 Mar 25.


Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.

Sharma SM, Sif S, Ostrowski MC, Sankar U.

J Cell Physiol. 2009 Jul;220(1):230-7. doi: 10.1002/jcp.21755.


Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors.

Hu R, Sharma SM, Bronisz A, Srinivasan R, Sankar U, Ostrowski MC.

Mol Cell Biol. 2007 Jun;27(11):4018-27. Epub 2007 Apr 2.


Mitf-PU.1 interactions with the tartrate-resistant acid phosphatase gene promoter during osteoclast differentiation.

Partington GA, Fuller K, Chambers TJ, Pondel M.

Bone. 2004 Feb;34(2):237-45.


The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.

Mansky KC, Sulzbacher S, Purdom G, Nelsen L, Hume DA, Rehli M, Ostrowski MC.

J Leukoc Biol. 2002 Feb;71(2):304-10.


MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.

Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S, Ostrowski MC.

J Biol Chem. 2007 May 25;282(21):15921-9. Epub 2007 Apr 2.


Involvement of upstream stimulatory factors 1 and 2 in RANKL-induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation.

Liu Y, Shi Z, Silveira A, Liu J, Sawadogo M, Yang H, Feng X.

J Biol Chem. 2003 Jun 6;278(23):20603-11. Epub 2003 Mar 27.


Regulation of the murine TRACP gene promoter.

Cassady AI, Luchin A, Ostrowski MC, Hume DA.

J Bone Miner Res. 2003 Oct;18(10):1901-4.


Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation.

Luchin A, Suchting S, Merson T, Rosol TJ, Hume DA, Cassady AI, Ostrowski MC.

J Biol Chem. 2001 Sep 28;276(39):36703-10. Epub 2001 Jul 31.


Enhancement of RANKL-induced MITF-E expression and osteoclastogenesis by TGF-β.

Asai K, Funaba M, Murakami M.

Cell Biochem Funct. 2014 Jul;32(5):401-9. doi: 10.1002/cbf.3028. Epub 2014 Feb 12.


A customized retroviral vector confers marker gene expression in osteoclast lineage cells.

Selski DJ, Clohisy DR.

J Cell Biochem. 2006 Feb 15;97(3):641-50.


Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.

So H, Rho J, Jeong D, Park R, Fisher DE, Ostrowski MC, Choi Y, Kim N.

J Biol Chem. 2003 Jun 27;278(26):24209-16. Epub 2003 Apr 13.


Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling.

Mansky KC, Sankar U, Han J, Ostrowski MC.

J Biol Chem. 2002 Mar 29;277(13):11077-83. Epub 2002 Jan 15.

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