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Items: 1 to 20 of 99

1.

Identification of CKAP4/p63 as a major substrate of the palmitoyl acyltransferase DHHC2, a putative tumor suppressor, using a novel proteomics method.

Zhang J, Planey SL, Ceballos C, Stevens SM Jr, Keay SK, Zacharias DA.

Mol Cell Proteomics. 2008 Jul;7(7):1378-88. doi: 10.1074/mcp.M800069-MCP200. Epub 2008 Feb 22.

2.

Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling.

Planey SL, Keay SK, Zhang CO, Zacharias DA.

Mol Biol Cell. 2009 Mar;20(5):1454-63. doi: 10.1091/mbc.E08-08-0849. Epub 2009 Jan 14.

3.

Purification and biochemical characterization of a protein-palmitoyl acyltransferase from human erythrocytes.

Das AK, Dasgupta B, Bhattacharya R, Basu J.

J Biol Chem. 1997 Apr 25;272(17):11021-5.

4.

Mutational analysis of Saccharomyces cerevisiae Erf2 reveals a two-step reaction mechanism for protein palmitoylation by DHHC enzymes.

Mitchell DA, Mitchell G, Ling Y, Budde C, Deschenes RJ.

J Biol Chem. 2010 Dec 3;285(49):38104-14. doi: 10.1074/jbc.M110.169102. Epub 2010 Sep 17.

5.

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity.

Huang K, Sanders S, Singaraja R, Orban P, Cijsouw T, Arstikaitis P, Yanai A, Hayden MR, El-Husseini A.

FASEB J. 2009 Aug;23(8):2605-15. doi: 10.1096/fj.08-127399. Epub 2009 Mar 19.

6.

Protein Palmitoylation by DHHC Protein Family.

Fukata Y, Bredt DS, Fukata M.

In: Kittler JT, Moss SJ, editors. The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology. Boca Raton (FL): CRC Press/Taylor & Francis; 2006. Chapter 5.

7.

The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain.

Greaves J, Carmichael JA, Chamberlain LH.

Mol Biol Cell. 2011 Jun 1;22(11):1887-95. doi: 10.1091/mbc.E10-11-0924. Epub 2011 Apr 6.

8.

Prognostic significance of cytoskeleton-associated membrane protein 4 and its palmitoyl acyltransferase DHHC2 in hepatocellular carcinoma.

Li SX, Tang GS, Zhou DX, Pan YF, Tan YX, Zhang J, Zhang B, Ding ZW, Liu LJ, Jiang TY, Hu HP, Dong LW, Wang HY.

Cancer. 2014 May 15;120(10):1520-31. doi: 10.1002/cncr.28593. Epub 2014 Feb 22.

9.

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.

Oku S, Takahashi N, Fukata Y, Fukata M.

J Biol Chem. 2013 Jul 5;288(27):19816-29. doi: 10.1074/jbc.M112.431676. Epub 2013 May 16.

10.

Palmitoyl acyltransferases, their substrates, and novel assays to connect them (Review).

Planey SL, Zacharias DA.

Mol Membr Biol. 2009 Jan;26(1):14-31. doi: 10.1080/09687680802646703. Review.

PMID:
19191172
11.

DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificities.

Jennings BC, Linder ME.

J Biol Chem. 2012 Mar 2;287(10):7236-45. doi: 10.1074/jbc.M111.337246. Epub 2012 Jan 13.

12.

Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs.

Varner AS, Ducker CE, Xia Z, Zhuang Y, De Vos ML, Smith CD.

Biochem J. 2003 Jul 1;373(Pt 1):91-9.

13.

A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening.

Hamel LD, Deschenes RJ, Mitchell DA.

Anal Biochem. 2014 Sep 1;460:1-8. doi: 10.1016/j.ab.2014.05.013. Epub 2014 May 27.

PMID:
24878334
14.

2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro.

Jennings BC, Nadolski MJ, Ling Y, Baker MB, Harrison ML, Deschenes RJ, Linder ME.

J Lipid Res. 2009 Feb;50(2):233-42. doi: 10.1194/jlr.M800270-JLR200. Epub 2008 Sep 30.

15.

Specificity of transmembrane protein palmitoylation in yeast.

González Montoro A, Chumpen Ramirez S, Quiroga R, Valdez Taubas J.

PLoS One. 2011 Feb 24;6(2):e16969. doi: 10.1371/journal.pone.0016969.

16.

DHHC palmitoyl transferases: substrate interactions and (patho)physiology.

Greaves J, Chamberlain LH.

Trends Biochem Sci. 2011 May;36(5):245-53. doi: 10.1016/j.tibs.2011.01.003. Epub 2011 Mar 8. Review.

PMID:
21388813
17.

Mechanism and function of DHHC S-acyltransferases.

Linder ME, Jennings BC.

Biochem Soc Trans. 2013 Feb 1;41(1):29-34. doi: 10.1042/BST20120328.

PMID:
23356254
18.
19.

Analysis of DHHC acyltransferases implies overlapping substrate specificity and a two-step reaction mechanism.

Hou H, John Peter AT, Meiringer C, Subramanian K, Ungermann C.

Traffic. 2009 Aug;10(8):1061-73. doi: 10.1111/j.1600-0854.2009.00925.x. Epub 2009 May 12.

20.

Substrate recognition by the cell surface palmitoyl transferase DHHC5.

Howie J, Reilly L, Fraser NJ, Vlachaki Walker JM, Wypijewski KJ, Ashford ML, Calaghan SC, McClafferty H, Tian L, Shipston MJ, Boguslavskyi A, Shattock MJ, Fuller W.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17534-9. doi: 10.1073/pnas.1413627111. Epub 2014 Nov 24.

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