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Items: 1 to 20 of 113


Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance.

Barron L, Knoechel B, Lohr J, Abbas AK.

J Immunol. 2008 Mar 1;180(5):2762-6.


Differential roles for Bim and Nur77 in thymocyte clonal deletion induced by ubiquitous self-antigen.

Hu QN, Baldwin TA.

J Immunol. 2015 Mar 15;194(6):2643-53. doi: 10.4049/jimmunol.1400030. Epub 2015 Feb 16.


Loss of the proapoptotic protein, Bim, breaks B cell anergy.

Oliver PM, Vass T, Kappler J, Marrack P.

J Exp Med. 2006 Mar 20;203(3):731-41. Epub 2006 Mar 6.


Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells.

Zhan Y, Zhang Y, Gray D, Carrington EM, Bouillet P, Ko HJ, O'Reilly L, Wicks IP, Strasser A, Lew AM.

J Immunol. 2011 Aug 15;187(4):1566-77. doi: 10.4049/jimmunol.1100027. Epub 2011 Jul 8.


Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.

Suen AY, Baldwin TA.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):893-8. doi: 10.1073/pnas.1114834109. Epub 2012 Jan 3.


Bim-mediated apoptosis is not necessary for thymic negative selection to ubiquitous self-antigens.

Hu Q, Sader A, Parkman JC, Baldwin TA.

J Immunol. 2009 Dec 15;183(12):7761-7. doi: 10.4049/jimmunol.0902181.


Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory.

Wojciechowski S, Jordan MB, Zhu Y, White J, Zajac AJ, Hildeman DA.

Eur J Immunol. 2006 Jul;36(7):1694-706.


MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation.

O'Reilly LA, Kruse EA, Puthalakath H, Kelly PN, Kaufmann T, Huang DC, Strasser A.

J Immunol. 2009 Jul 1;183(1):261-9. doi: 10.4049/jimmunol.0803853.


Deletion, but not anergy, is involved in TGF-beta-treated antigen-presenting cell-induced tolerance.

Alard P, Clark SL, Kosiewicz MM.

Int Immunol. 2003 Aug;15(8):945-53.


Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.

Daley SR, Hu DY, Goodnow CC.

J Exp Med. 2013 Feb 11;210(2):269-85. doi: 10.1084/jem.20121458. Epub 2013 Jan 21.


Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways.

Szymczak-Workman AL, Delgoffe GM, Green DR, Vignali DA.

J Immunol. 2011 Nov 1;187(9):4416-20. doi: 10.4049/jimmunol.1100548. Epub 2011 Sep 26.


Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells.

Marth T, Zeitz M, Ludviksson BR, Strober W, Kelsall BL.

J Immunol. 1999 Jun 15;162(12):7233-40.


Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision.

Hale JS, Nelson LT, Simmons KB, Fink PJ.

J Immunol. 2011 Jan 15;186(2):799-806. doi: 10.4049/jimmunol.1002933. Epub 2010 Dec 10.


The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis.

Lauer C, Brunner T, Corazza N.

J Immunol. 2012 Jan 15;188(2):916-22. doi: 10.4049/jimmunol.1101864. Epub 2011 Dec 7.


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