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Items: 1 to 20 of 49


Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation.

Bijlsma MF, Peppelenbosch MP, Spek CA, Roelink H.

Stem Cells. 2008 May;26(5):1138-45. doi: 10.1634/stemcells.2007-0841. Epub 2008 Feb 21.


Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.

Bijlsma MF, Borensztajn KS, Roelink H, Peppelenbosch MP, Spek CA.

Cell Signal. 2007 Dec;19(12):2596-604. Epub 2007 Aug 24.


Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines.

Lipinski RJ, Bijlsma MF, Gipp JJ, Podhaizer DJ, Bushman W.

BMC Cell Biol. 2008 Sep 13;9:49. doi: 10.1186/1471-2121-9-49.


The path to chemotaxis and transcription is smoothened.

Lin C, Nozawa YI, Chuang PT.

Sci Signal. 2012 Aug 21;5(238):pe35. doi: 10.1126/scisignal.2003423.


Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors.

Merchant A, Joseph G, Wang Q, Brennan S, Matsui W.

Blood. 2010 Mar 25;115(12):2391-6. doi: 10.1182/blood-2009-09-241703. Epub 2010 Jan 27.


Noncanonical Hedgehog signaling.

Brennan D, Chen X, Cheng L, Mahoney M, Riobo NA.

Vitam Horm. 2012;88:55-72. doi: 10.1016/B978-0-12-394622-5.00003-1. Review.


The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling.

Sekimizu K, Nishioka N, Sasaki H, Takeda H, Karlstrom RO, Kawakami A.

Development. 2004 Jun;131(11):2521-32. Epub 2004 Apr 28.


Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.

Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L.

EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4.


Indian hedgehog signaling in extraembryonic endoderm and ectoderm differentiation in ES embryoid bodies.

Maye P, Becker S, Kasameyer E, Byrd N, Grabel L.

Mech Dev. 2000 Jun;94(1-2):117-32.


Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.

Svärd J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, Bergström A, Ericson J, Toftgård R, Teglund S.

Dev Cell. 2006 Feb;10(2):187-97. Erratum in: Dev Cell. 2006 Mar;10(3):409. Henricson, Karin Heby [corrected to Heby-Henricson, Karin].


The primary cilia, a 'Rab-id' transit system for hedgehog signaling.

Oro AE.

Curr Opin Cell Biol. 2007 Dec;19(6):691-6. Epub 2007 Dec 3. Review.


Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells.

van der Horst G, Farih-Sips H, Löwik CW, Karperien M.

Bone. 2003 Dec;33(6):899-910.


Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane.

Shinozaki S, Ohnishi H, Hama K, Kita H, Yamamoto H, Osawa H, Sato K, Tamada K, Mashima H, Sugano K.

J Cell Physiol. 2008 Jul;216(1):38-46. doi: 10.1002/jcp.21372.


Expression of hedgehog signalling components in adult mouse testis.

Szczepny A, Hime GR, Loveland KL.

Dev Dyn. 2006 Nov;235(11):3063-70.


Cell signaling. A ciliary signaling switch.

Christensen ST, Ott CM.

Science. 2007 Jul 20;317(5836):330-1. No abstract available.


Cilia and Hedgehog responsiveness in the mouse.

Huangfu D, Anderson KV.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30. Epub 2005 Aug 1.


Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.

Dennler S, André J, Alexaki I, Li A, Magnaldo T, ten Dijke P, Wang XJ, Verrecchia F, Mauviel A.

Cancer Res. 2007 Jul 15;67(14):6981-6.


Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists.

Frank-Kamenetsky M, Zhang XM, Bottega S, Guicherit O, Wichterle H, Dudek H, Bumcrot D, Wang FY, Jones S, Shulok J, Rubin LL, Porter JA.

J Biol. 2002 Nov 6;1(2):10.

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