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Items: 1 to 20 of 84

1.

Proportionally more deleterious genetic variation in European than in African populations.

Lohmueller KE, Indap AR, Schmidt S, Boyko AR, Hernandez RD, Hubisz MJ, Sninsky JJ, White TJ, Sunyaev SR, Nielsen R, Clark AG, Bustamante CD.

Nature. 2008 Feb 21;451(7181):994-7. doi: 10.1038/nature06611.

2.

Mitochondrial pathogenic mutations are population-specific.

Breen MS, Kondrashov FA.

Biol Direct. 2010 Dec 31;5:68. doi: 10.1186/1745-6150-5-68.

3.

Characteristics of neutral and deleterious protein-coding variation among individuals and populations.

Fu W, Gittelman RM, Bamshad MJ, Akey JM.

Am J Hum Genet. 2014 Oct 2;95(4):421-36. doi: 10.1016/j.ajhg.2014.09.006.

4.

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.

Fu W, O'Connor TD, Jun G, Kang HM, Abecasis G, Leal SM, Gabriel S, Rieder MJ, Altshuler D, Shendure J, Nickerson DA, Bamshad MJ; NHLBI Exome Sequencing Project, Akey JM.

Nature. 2013 Jan 10;493(7431):216-20. doi: 10.1038/nature11690. Epub 2012 Nov 28. Erratum in: Nature. 2013 Mar 14;495(7440):270. Rieder, Mark J [added].

5.

Identification of functionally variant MDR1 alleles among European Americans and African Americans.

Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, Taylor A, Xie HG, McKinsey J, Zhou S, Lan LB, Schuetz JD, Schuetz EG, Wilkinson GR.

Clin Pharmacol Ther. 2001 Aug;70(2):189-99.

PMID:
11503014
6.

Functional and Structural Consequence of Rare Exonic Single Nucleotide Polymorphisms: One Story, Two Tales.

Gu W, Gurguis CI, Zhou JJ, Zhu Y, Ko EA, Ko JH, Wang T, Zhou T.

Genome Biol Evol. 2015 Oct 9;7(10):2929-40. doi: 10.1093/gbe/evv191.

7.

Synonymous SNPs provide evidence for selective constraint on human exonic splicing enhancers.

Carlini DB, Genut JE.

J Mol Evol. 2006 Jan;62(1):89-98. Epub 2005 Nov 30.

PMID:
16320116
8.

Long runs of homozygosity are enriched for deleterious variation.

Szpiech ZA, Xu J, Pemberton TJ, Peng W, Zöllner S, Rosenberg NA, Li JZ.

Am J Hum Genet. 2013 Jul 11;93(1):90-102. doi: 10.1016/j.ajhg.2013.05.003. Epub 2013 Jun 6.

9.

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA.

Mol Psychiatry. 2014 Jan;19(1):41-9. doi: 10.1038/mp.2013.145. Epub 2013 Oct 29.

10.

DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection.

Wooding SP, Watkins WS, Bamshad MJ, Dunn DM, Weiss RB, Jorde LB.

Am J Hum Genet. 2002 Sep;71(3):528-42. Epub 2002 Aug 9.

11.

Population-specific common SNPs reflect demographic histories and highlight regions of genomic plasticity with functional relevance.

Choudhury A, Hazelhurst S, Meintjes A, Achinike-Oduaran O, Aron S, Gamieldien J, Jalali Sefid Dashti M, Mulder N, Tiffin N, Ramsay M.

BMC Genomics. 2014 Jun 6;15:437. doi: 10.1186/1471-2164-15-437.

12.

Abundant sequence divergence in the native Japanese cattle Mishima-Ushi (Bos taurus) detected using whole-genome sequencing.

Tsuda K, Kawahara-Miki R, Sano S, Imai M, Noguchi T, Inayoshi Y, Kono T.

Genomics. 2013 Oct;102(4):372-8. doi: 10.1016/j.ygeno.2013.08.002. Epub 2013 Aug 9.

13.

Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa.

Alkan C, Kavak P, Somel M, Gokcumen O, Ugurlu S, Saygi C, Dal E, Bugra K, Güngör T, Sahinalp SC, Özören N, Bekpen C.

BMC Genomics. 2014 Nov 7;15:963. doi: 10.1186/1471-2164-15-963.

14.

Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.

Ittiwut R, Listman JB, Ittiwut C, Cubells JF, Weiss RD, Brady K, Oslin D, Farrer LA, Kranzler HR, Gelernter J.

Am J Med Genet B Neuropsychiatr Genet. 2011 Sep;156B(6):651-60. doi: 10.1002/ajmg.b.31205. Epub 2011 Jun 8.

15.

Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.

Gorlov IP, Gorlova OY, Sunyaev SR, Spitz MR, Amos CI.

Am J Hum Genet. 2008 Jan;82(1):100-12. doi: 10.1016/j.ajhg.2007.09.006.

16.
17.

Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates.

Pimenoff VN, Laval G, Comas D, Palo JU, Gut I, Cann H, Excoffier L, Sajantila A.

Pharmacogenet Genomics. 2012 Dec;22(12):846-57. doi: 10.1097/FPC.0b013e32835a3a6d.

PMID:
23089684
18.

Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans.

Nothnagel M, Lu TT, Kayser M, Krawczak M.

Hum Mol Genet. 2010 Aug 1;19(15):2927-35. doi: 10.1093/hmg/ddq198. Epub 2010 May 12.

PMID:
20462934
19.

Characterization of single-nucleotide variation in Indian-origin rhesus macaques (Macaca mulatta).

Fawcett GL, Raveendran M, Deiros DR, Chen D, Yu F, Harris RA, Ren Y, Muzny DM, Reid JG, Wheeler DA, Worley KC, Shelton SE, Kalin NH, Milosavljevic A, Gibbs R, Rogers J.

BMC Genomics. 2011 Jun 13;12:311. doi: 10.1186/1471-2164-12-311.

20.

A comparison of type 2 diabetes risk allele load between African Americans and European Americans.

Keaton JM, Cooke Bailey JN, Palmer ND, Freedman BI, Langefeld CD, Ng MC, Bowden DW.

Hum Genet. 2014 Dec;133(12):1487-95. doi: 10.1007/s00439-014-1486-5. Epub 2014 Oct 2.

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