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Items: 1 to 20 of 95

1.

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.

Calzascia T, Pellegrini M, Lin A, Garza KM, Elford AR, Shahinian A, Ohashi PS, Mak TW.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2999-3004. doi: 10.1073/pnas.0712135105. Epub 2008 Feb 14.

2.

Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions.

Le Saout C, Mennechet S, Taylor N, Hernandez J.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19414-9. doi: 10.1073/pnas.0807743105. Epub 2008 Nov 25.

4.

Distinct regulation of autoreactive CD4 T cell expansion by interleukin-4 under conditions of lymphopenia.

Hill NJ, Stotland AB, Sarvetnick NE.

J Leukoc Biol. 2007 Mar;81(3):757-65. Epub 2006 Dec 12.

PMID:
17164429
5.

IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions.

Le Saout C, Villard M, Cabasse C, Jacquet C, Taylor N, Hernandez J.

PLoS One. 2010 Sep 10;5(9):e12659. doi: 10.1371/journal.pone.0012659.

6.

Development of memory-like autoregulatory CD8+ T cells is CD4+ T cell dependent.

Shameli A, Clemente-Casares X, Wang J, Santamaria P.

J Immunol. 2011 Sep 15;187(6):2859-66. doi: 10.4049/jimmunol.1101117. Epub 2011 Aug 8.

7.

IL-2 and IL-7 determine the homeostatic balance between the regulatory and conventional CD4+ T cell compartments during peripheral T cell reconstitution.

Le Campion A, Pommier A, Delpoux A, Stouvenel L, Auffray C, Martin B, Lucas B.

J Immunol. 2012 Oct 1;189(7):3339-46. Epub 2012 Aug 29.

8.

Exposure to IL-15 and IL-21 enables autoreactive CD8 T cells to respond to weak antigens and cause disease in a mouse model of autoimmune diabetes.

Ramanathan S, Dubois S, Chen XL, Leblanc C, Ohashi PS, Ilangumaran S.

J Immunol. 2011 May 1;186(9):5131-41. doi: 10.4049/jimmunol.1001221. Epub 2011 Mar 23.

9.

B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets.

Yadav D, Judkowski V, Flodstrom-Tullberg M, Sterling L, Redmond WL, Sherman L, Sarvetnick N.

J Immunol. 2004 Sep 15;173(6):3631-9.

10.

CD4(+)CD25(+) T-cells control autoimmunity in the absence of B-cells.

Mariño E, Villanueva J, Walters S, Liuwantara D, Mackay F, Grey ST.

Diabetes. 2009 Jul;58(7):1568-77. doi: 10.2337/db08-1504. Epub 2009 Mar 31.

11.
13.
14.

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

King C, Ilic A, Koelsch K, Sarvetnick N.

Cell. 2004 Apr 16;117(2):265-77.

15.

Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

Homann D, Holz A, Bot A, Coon B, Wolfe T, Petersen J, Dyrberg TP, Grusby MJ, von Herrath MG.

Immunity. 1999 Oct;11(4):463-72.

16.

Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.

Petzold C, Riewaldt J, Koenig T, Schallenberg S, Kretschmer K.

Rev Diabet Stud. 2010 Spring;7(1):47-61. doi: 10.1900/RDS.2010.7.47. Epub 2010 May 10.

17.

Interleukin-7 is a survival factor for CD4+ CD25+ T-cells and is expressed by diabetes-suppressive dendritic cells.

Harnaha J, Machen J, Wright M, Lakomy R, Styche A, Trucco M, Makaroun S, Giannoukakis N.

Diabetes. 2006 Jan;55(1):158-70.

18.

Control of autoimmunity by naturally arising regulatory CD4+ T cells.

Hori S, Takahashi T, Sakaguchi S.

Adv Immunol. 2003;81:331-71. Review.

PMID:
14711059
19.

Suppressor T cells--they're back and critical for regulation of autoimmunity!

Chatenoud L, Salomon B, Bluestone JA.

Immunol Rev. 2001 Aug;182:149-63. Review.

PMID:
11722631
20.

Mechanisms of PDL1-mediated regulation of autoimmune diabetes.

Guleria I, Gubbels Bupp M, Dada S, Fife B, Tang Q, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P, Yagita H, Azuma M, Atkinson M, Bluestone JA, Sayegh MH.

Clin Immunol. 2007 Oct;125(1):16-25. Epub 2007 Jul 12.

PMID:
17627890

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