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Items: 1 to 20 of 177


IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses.

Lye E, Dhanji S, Calzascia T, Elford AR, Ohashi PS.

Eur J Immunol. 2008 Mar;38(3):870-6. doi: 10.1002/eji.200737429.


Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4.

Suzuki N, Suzuki S, Duncan GS, Millar DG, Wada T, Mirtsos C, Takada H, Wakeham A, Itie A, Li S, Penninger JM, Wesche H, Ohashi PS, Mak TW, Yeh WC.

Nature. 2002 Apr 18;416(6882):750-6. Epub 2002 Mar 31.


Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections.

Bachmann MF, Wolint P, Walton S, Schwarz K, Oxenius A.

Eur J Immunol. 2007 Jun;37(6):1502-12.


Interleukin-1 receptor-associated kinase 4 is essential for initial host control of Brucella abortus infection.

Oliveira FS, Carvalho NB, Brandão AP, Gomes MT, de Almeida LA, Oliveira SC.

Infect Immun. 2011 Nov;79(11):4688-95. doi: 10.1128/IAI.05289-11. Epub 2011 Aug 15.


The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation.

Koziczak-Holbro M, Littlewood-Evans A, Pöllinger B, Kovarik J, Dawson J, Zenke G, Burkhart C, Müller M, Gram H.

Arthritis Rheum. 2009 Jun;60(6):1661-71. doi: 10.1002/art.24552.


IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression.

Koziczak-Holbro M, Joyce C, Glück A, Kinzel B, Müller M, Tschopp C, Mathison JC, Davis CN, Gram H.

J Biol Chem. 2007 May 4;282(18):13552-60. Epub 2007 Mar 2.


IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes.

Koziczak-Holbro M, Glück A, Tschopp C, Mathison JC, Gram H.

Eur J Immunol. 2008 Mar;38(3):788-96. doi: 10.1002/eji.200737886.


Vaccination with an adenoviral vector encoding the tumor antigen directly linked to invariant chain induces potent CD4(+) T-cell-independent CD8(+) T-cell-mediated tumor control.

Sorensen MR, Holst PJ, Pircher H, Christensen JP, Thomsen AR.

Eur J Immunol. 2009 Oct;39(10):2725-36. doi: 10.1002/eji.200939543.


Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells.

Matter MS, Hilmenyuk T, Claus C, Marone R, Schürch C, Tinguely M, Terracciano L, Luther SA, Ochsenbein AF.

PLoS One. 2011;6(9):e24772. doi: 10.1371/journal.pone.0024772. Epub 2011 Sep 23.


Impaired anti-viral T cell responses due to expression of the Ly49A inhibitory receptor.

Zajac AJ, Vance RE, Held W, Sourdive DJ, Altman JD, Raulet DH, Ahmed R.

J Immunol. 1999 Nov 15;163(10):5526-34.


IL-12 is not required for induction of type 1 cytokine responses in viral infections.

Oxenius A, Karrer U, Zinkernagel RM, Hengartner H.

J Immunol. 1999 Jan 15;162(2):965-73.


CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus.

Thomsen AR, Nansen A, Christensen JP, Andreasen SO, Marker O.

J Immunol. 1998 Nov 1;161(9):4583-90.


Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.

Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF.

Immunology. 2010 Mar;129(3):363-74. doi: 10.1111/j.1365-2567.2009.03179.x. Epub 2009 Nov 16.


Solving the IRAK-4 enigma: application of kinase-dead knock-in mice.

Koziczak-Holbro M, Joyce C, Glück A, Kinzel B, Müller M, Gram H.

Ernst Schering Found Symp Proc. 2007;(3):63-82.


4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses.

Tan JT, Whitmire JK, Ahmed R, Pearson TC, Larsen CP.

J Immunol. 1999 Nov 1;163(9):4859-68.


Hyperthermia differentially regulates TLR4 and TLR2-mediated innate immune response.

Zhao W, An H, Zhou J, Xu H, Yu Y, Cao X.

Immunol Lett. 2007 Feb 15;108(2):137-42. Epub 2006 Dec 19.


CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses.

Whitmire JK, Flavell RA, Grewal IS, Larsen CP, Pearson TC, Ahmed R.

J Immunol. 1999 Sep 15;163(6):3194-201.


Effects of IL-12 on the response and susceptibility to experimental viral infections.

Orange JS, Wolf SF, Biron CA.

J Immunol. 1994 Feb 1;152(3):1253-64.


Tumor-infiltrating lymphocytes exhibiting high ex vivo cytolytic activity fail to prevent murine melanoma tumor growth in vivo.

Prévost-Blondel A, Zimmermann C, Stemmer C, Kulmburg P, Rosenthal FM, Pircher H.

J Immunol. 1998 Sep 1;161(5):2187-94.

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