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Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer.

Golden T, Aragon IV, Rutland B, Tucker JA, Shevde LA, Samant RS, Zhou G, Amable L, Skarra D, Honkanen RE.

Biochim Biophys Acta. 2008 Apr;1782(4):259-70. doi: 10.1016/j.bbadis.2008.01.004. Epub 2008 Jan 26.


Identification of an estrogen-inducible phosphatase (PP5) that converts MCF-7 human breast carcinoma cells into an estrogen-independent phenotype when expressed constitutively.

Urban G, Golden T, Aragon IV, Scammell JG, Dean NM, Honkanen RE.

J Biol Chem. 2001 Jul 20;276(29):27638-46. Epub 2001 Apr 30.


Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade.

Zhou G, Golden T, Aragon IV, Honkanen RE.

J Biol Chem. 2004 Nov 5;279(45):46595-605. Epub 2004 Aug 24.


Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice.

Golden T, Aragon IV, Zhou G, Cooper SR, Dean NM, Honkanen RE.

Cancer Lett. 2004 Nov 8;215(1):95-100.


Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1).

Amable L, Grankvist N, Largen JW, Ortsäter H, Sjöholm Å, Honkanen RE.

J Biol Chem. 2011 Nov 25;286(47):40413-22. doi: 10.1074/jbc.M111.244053. Epub 2011 Sep 15.


Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.

Huang S, Shu L, Easton J, Harwood FC, Germain GS, Ichijo H, Houghton PJ.

J Biol Chem. 2004 Aug 27;279(35):36490-6. Epub 2004 Jun 24.


Cyclooxygenase-2 and human epidermal growth factor receptor type 2 (HER-2) expression simultaneously in invasive and in situ breast ductal carcinoma.

Lucarelli AP, Martins MM, Montor W, Oliveira V, Galvão MA, Piato S.

Sao Paulo Med J. 2011 Dec;129(6):371-9.


Silencing of HSulf-2 expression in cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo.

Khurana A, McKean H, Kim H, Kim SH, mcguire J, Roberts LR, Goetz MP, Shridhar V.

Breast Cancer Res. 2012 Mar 12;14(2):R43.


Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis.

Bi X, Hameed M, Mirani N, Pimenta EM, Anari J, Barnes BJ.

Breast Cancer Res. 2011;13(6):R111. doi: 10.1186/bcr3053. Epub 2011 Nov 4.


Protein kinase C alpha expression in normal breast, ductal carcinoma in situ and invasive ductal carcinoma.

Ainsworth PD, Winstanley JH, Pearson JM, Bishop HM, Garrod DR.

Eur J Cancer. 2004 Oct;40(15):2269-73.


[Aromatase expression in invasive and in situ ductal carcinoma present in the same breast].

Oliveira VM, Ribeiro Lde S, Rossi LM, Silva MA, Aldrighi JM, Bagnoli F, Rinaldi JF, Aoki T.

Rev Assoc Med Bras (1992). 2009 Nov-Dec;55(6):651-5. Portuguese.


Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest.

Zuo Z, Urban G, Scammell JG, Dean NM, McLean TK, Aragon I, Honkanen RE.

Biochemistry. 1999 Jul 13;38(28):8849-57.


Nek2A contributes to tumorigenic growth and possibly functions as potential therapeutic target for human breast cancer.

Wang S, Li W, Liu N, Zhang F, Liu H, Liu F, Liu J, Zhang T, Niu Y.

J Cell Biochem. 2012 Jun;113(6):1904-14. doi: 10.1002/jcb.24059.


Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression.

Suzuki J, Chen YY, Scott GK, Devries S, Chin K, Benz CC, Waldman FM, Hwang ES.

Clin Cancer Res. 2009 May 1;15(9):3163-71. doi: 10.1158/1078-0432.CCR-08-2319. Epub 2009 Apr 21.


Telomerase activity in ductal carcinoma in situ of the breast.

Shpitz B, Zimlichman S, Zemer R, Bomstein Y, Zehavi T, Liverant S, Bernehim J, Kaufman Z, Klein E, Shapira Y, Klein A.

Breast Cancer Res Treat. 1999 Nov;58(1):65-9.


Annexin-1 regulates growth arrest induced by high levels of estrogen in MCF-7 breast cancer cells.

Ang EZ, Nguyen HT, Sim HL, Putti TC, Lim LH.

Mol Cancer Res. 2009 Feb;7(2):266-74. doi: 10.1158/1541-7786.MCR-08-0147. Epub 2009 Feb 10.


Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression.

Urban G, Golden T, Aragon IV, Cowsert L, Cooper SR, Dean NM, Honkanen RE.

J Biol Chem. 2003 Mar 14;278(11):9747-53. Epub 2003 Jan 7.


[Expression of fatty acid synthase and its association with HER2 in invasive ductal carcinoma of breast].

Yang M, Xu SP, Ao QL.

Zhonghua Bing Li Xue Za Zhi. 2013 Apr;42(4):257-61. doi: 10.3760/cma.j.issn.0529-5807.2013.04.010. Chinese.


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