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Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels.

Saiardi A, Cockcroft S.

Sci Signal. 2008 Jan 29;1(4):pe5. doi: 10.1126/stke.14pe5. Review. Erratum in: Sci Signal. 2008;1(7):er1.


Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1.

Zhou Y, Wu S, Wang H, Hayakawa Y, Bird GS, Shears SB.

Biochem J. 2012 Dec 1;448(2):273-83. doi: 10.1042/BJ20120730.


Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate.

Chang SC, Majerus PW.

Biochem Biophys Res Commun. 2006 Jan 6;339(1):209-16. Epub 2005 Nov 10.


The metabolism of D-myo-inositol 1,4,5-trisphosphate and D-myo-inositol 1,3,4,5-tetrakisphosphate by porcine skeletal muscle.

Foster PS, Hogan SP, Hansbro PM, O'Brien R, Potter BV, Ozaki S, Denborough MA.

Eur J Biochem. 1994 Jun 15;222(3):955-64.


Phosphorylation of inositol 1,4,5-trisphosphate analogues by 3-kinase and dephosphorylation of inositol 1,3,4,5-tetrakisphosphate analogues by 5-phosphatase.

Van Dijken P, Lammers AA, Ozaki S, Potter BV, Erneux C, Van Haastert PJ.

Eur J Biochem. 1994 Dec 1;226(2):561-6.


A novel, phospholipase C-independent pathway of inositol 1,4,5-trisphosphate formation in Dictyostelium and rat liver.

Van Dijken P, de Haas JR, Craxton A, Erneux C, Shears SB, Van Haastert PJ.

J Biol Chem. 1995 Dec 15;270(50):29724-31.


Integration of inositol phosphate signaling pathways via human ITPK1.

Chamberlain PP, Qian X, Stiles AR, Cho J, Jones DH, Lesley SA, Grabau EA, Shears SB, Spraggon G.

J Biol Chem. 2007 Sep 21;282(38):28117-25. Epub 2007 Jul 6.


Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.

Yang X, Rudolf M, Carew MA, Yoshida M, Nerreter V, Riley AM, Chung SK, Bruzik KS, Potter BV, Schultz C, Shears SB.

J Biol Chem. 1999 Jul 2;274(27):18973-80.


Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities.

Wilcox RA, Safrany ST, Lampe D, Mills SJ, Nahorski SR, Potter BV.

Eur J Biochem. 1994 Jul 1;223(1):115-24.


Molecular basis for the integration of inositol phosphate signaling pathways via human ITPK1.

Shears SB.

Adv Enzyme Regul. 2009;49(1):87-96. doi: 10.1016/j.advenzreg.2008.12.008. Epub 2009 Jan 3. Review. No abstract available.


Regulation of histamine- and UTP-induced increases in Ins(1,4,5)P3, Ins (1,3,4,5)P4 and Ca2+ by cyclic AMP in DDT1 MF-2 cells.

Sipma H, Duin M, Hoiting B, den Hertog A, Nelemans A.

Br J Pharmacol. 1995 Jan;114(2):383-90.


Inositol polyphosphate metabolism and inositol lipids in a green alga, Chlamydomonas eugametos.

Irvine RF, Letcher AJ, Stephens LR, Musgrave A.

Biochem J. 1992 Jan 1;281 ( Pt 1):261-6.


The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes.

Connolly TM, Bansal VS, Bross TE, Irvine RF, Majerus PW.

J Biol Chem. 1987 Feb 15;262(5):2146-9.


The role of inositol 1,3,4,5-tetrakisphosphate in internal Ca2+ mobilization following histamine H1 receptor stimulation in DDT1 MF-2 cells.

Van der Zee L, Sipma H, Nelemans A, Den Hertog A.

Eur J Pharmacol. 1995 May 26;289(3):463-9.


Characterization of inositol 1,4,5-trisphosphate- and inositol 1,3,4,5-tetrakisphosphate-binding sites in rat cerebellum.

Challiss RA, Willcocks AL, Mulloy B, Potter BV, Nahorski SR.

Biochem J. 1991 Mar 15;274 ( Pt 3):861-7.

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