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Items: 1 to 20 of 223

1.

ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation.

McLachlan E, Plante I, Shao Q, Tong D, Kidder GM, Bernier SM, Laird DW.

J Bone Miner Res. 2008 Jun;23(6):928-38. doi: 10.1359/jbmr.080217.

2.

Functional characterization of oculodentodigital dysplasia-associated Cx43 mutants.

McLachlan E, Manias JL, Gong XQ, Lounsbury CS, Shao Q, Bernier SM, Bai D, Laird DW.

Cell Commun Adhes. 2005 Jul-Dec;12(5-6):279-92.

PMID:
16531323
3.

Differential potency of dominant negative connexin43 mutants in oculodentodigital dysplasia.

Gong XQ, Shao Q, Langlois S, Bai D, Laird DW.

J Biol Chem. 2007 Jun 29;282(26):19190-202. Epub 2007 Apr 9.

4.

Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant.

Manias JL, Plante I, Gong XQ, Shao Q, Churko J, Bai D, Laird DW.

Cardiovasc Res. 2008 Dec 1;80(3):385-95. doi: 10.1093/cvr/cvn203. Epub 2008 Aug 4.

PMID:
18678643
5.

Oculodentodigital dysplasia connexin43 mutations result in non-functional connexin hemichannels and gap junctions in C6 glioma cells.

Lai A, Le DN, Paznekas WA, Gifford WD, Jabs EW, Charles AC.

J Cell Sci. 2006 Feb 1;119(Pt 3):532-41. Epub 2006 Jan 17.

6.

Loss of connexin43-mediated gap junctional coupling in the mesenchyme of limb buds leads to altered expression of morphogens in mice.

Dobrowolski R, Hertig G, Lechner H, Wörsdörfer P, Wulf V, Dicke N, Eckert D, Bauer R, Schorle H, Willecke K.

Hum Mol Genet. 2009 Aug 1;18(15):2899-911. doi: 10.1093/hmg/ddp227. Epub 2009 May 12.

PMID:
19439426
7.

Modulation of connexin43 alters expression of osteoblastic differentiation markers.

Li Z, Zhou Z, Saunders MM, Donahue HJ.

Am J Physiol Cell Physiol. 2006 Apr;290(4):C1248-55. Epub 2005 Nov 30.

8.

Endothelin-1 inhibits human osteoblastic cell differentiation: influence of connexin-43 expression level.

Niger C, Geneau G, Fiorini C, Defamie N, Pointis G, Mesnil M, Cronier L.

J Cell Biochem. 2008 Jan 1;103(1):110-22.

PMID:
17486593
9.

Decreased levels of Cx43 gap junctions result in ameloblast dysregulation and enamel hypoplasia in Gja1Jrt/+ mice.

Toth K, Shao Q, Lorentz R, Laird DW.

J Cell Physiol. 2010 Jun;223(3):601-9. doi: 10.1002/jcp.22046.

PMID:
20127707
10.

A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia.

Flenniken AM, Osborne LR, Anderson N, Ciliberti N, Fleming C, Gittens JE, Gong XQ, Kelsey LB, Lounsbury C, Moreno L, Nieman BJ, Peterson K, Qu D, Roscoe W, Shao Q, Tong D, Veitch GI, Voronina I, Vukobradovic I, Wood GA, Zhu Y, Zirngibl RA, Aubin JE, Bai D, Bruneau BG, Grynpas M, Henderson JE, Henkelman RM, McKerlie C, Sled JG, Stanford WL, Laird DW, Kidder GM, Adamson SL, Rossant J.

Development. 2005 Oct;132(19):4375-86.

11.

Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43.

Upham BL, Suzuki J, Chen G, Wang Y, McCabe LR, Chang CC, Krutovskikh VA, Yamasaki H, Trosko JE.

Mol Carcinog. 2003 Aug;37(4):192-201.

PMID:
12891628
12.

Functional characterization of a GJA1 frameshift mutation causing oculodentodigital dysplasia and palmoplantar keratoderma.

Gong XQ, Shao Q, Lounsbury CS, Bai D, Laird DW.

J Biol Chem. 2006 Oct 20;281(42):31801-11. Epub 2006 Aug 6.

13.

Manipulating Cx43 expression triggers gene reprogramming events in dermal fibroblasts from oculodentodigital dysplasia patients.

Esseltine JL, Shao Q, Huang T, Kelly JJ, Sampson J, Laird DW.

Biochem J. 2015 Nov 15;472(1):55-69. doi: 10.1042/BJ20150652. Epub 2015 Sep 8.

PMID:
26349540
14.

Oculodentodigital dysplasia-causing connexin43 mutants are non-functional and exhibit dominant effects on wild-type connexin43.

Roscoe W, Veitch GI, Gong XQ, Pellegrino E, Bai D, McLachlan E, Shao Q, Kidder GM, Laird DW.

J Biol Chem. 2005 Mar 25;280(12):11458-66. Epub 2005 Jan 10.

15.

A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouse.

Tong D, Lu X, Wang HX, Plante I, Lui E, Laird DW, Bai D, Kidder GM.

Biol Reprod. 2009 Jun;80(6):1099-106. doi: 10.1095/biolreprod.108.071969. Epub 2009 Jan 28.

16.
17.

Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia.

Kozoriz MG, Lai S, Vega JL, Sáez JC, Sin WC, Bechberger JF, Naus CC.

Neuropharmacology. 2013 Dec;75:549-56. doi: 10.1016/j.neuropharm.2013.05.003. Epub 2013 May 31.

PMID:
23727526
18.

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling.

Watkins M, Grimston SK, Norris JY, Guillotin B, Shaw A, Beniash E, Civitelli R.

Mol Biol Cell. 2011 Apr 15;22(8):1240-51. doi: 10.1091/mbc.E10-07-0571. Epub 2011 Feb 23.

19.

Some oculodentodigital dysplasia-associated Cx43 mutations cause increased hemichannel activity in addition to deficient gap junction channels.

Dobrowolski R, Sommershof A, Willecke K.

J Membr Biol. 2007 Oct;219(1-3):9-17. Epub 2007 Aug 9.

PMID:
17687502
20.

Tbx2 represses expression of Connexin43 in osteoblastic-like cells.

Chen JR, Chatterjee B, Meyer R, Yu JC, Borke JL, Isales CM, Kirby ML, Lo CW, Bollag RJ.

Calcif Tissue Int. 2004 Jun;74(6):561-73.

PMID:
15354864

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