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Items: 1 to 20 of 77


The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase.

Zhang H, Macara IG.

Dev Cell. 2008 Feb;14(2):216-26. doi: 10.1016/j.devcel.2007.11.020.


Dialogue between RhoA/ROCK and members of the Par complex in cell polarity.

Sordella R, Van Aelst L.

Dev Cell. 2008 Feb;14(2):150-2. doi: 10.1016/j.devcel.2008.01.015.


The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis.

Zhang H, Macara IG.

Nat Cell Biol. 2006 Mar;8(3):227-37. Epub 2006 Feb 12.


Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity.

Chen YM, Wang QJ, Hu HS, Yu PC, Zhu J, Drewes G, Piwnica-Worms H, Luo ZG.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8534-9. Epub 2006 May 22.


Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.

Nakayama M, Goto TM, Sugimoto M, Nishimura T, Shinagawa T, Ohno S, Amano M, Kaibuchi K.

Dev Cell. 2008 Feb;14(2):205-15. doi: 10.1016/j.devcel.2007.11.021.


Local, persistent activation of Rho GTPases during plasticity of single dendritic spines.

Murakoshi H, Wang H, Yasuda R.

Nature. 2011 Apr 7;472(7341):100-4. doi: 10.1038/nature09823. Epub 2011 Mar 20.


The polarity protein partitioning-defective 1 (PAR-1) regulates dendritic spine morphogenesis through phosphorylating postsynaptic density protein 95 (PSD-95).

Wu Q, DiBona VL, Bernard LP, Zhang H.

J Biol Chem. 2012 Aug 31;287(36):30781-8. doi: 10.1074/jbc.M112.351452. Epub 2012 Jul 17.


Regulation of epithelial cell polarity by PAR-3 depends on Girdin transcription and Girdin-Gαi3 signaling.

Sasaki K, Kakuwa T, Akimoto K, Koga H, Ohno S.

J Cell Sci. 2015 Jul 1;128(13):2244-58. doi: 10.1242/jcs.160879. Epub 2015 May 14.


Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis.

Kusama T, Mukai M, Endo H, Ishikawa O, Tatsuta M, Nakamura H, Inoue M.

Cancer Sci. 2006 Sep;97(9):848-53. Epub 2006 Jun 14.


SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway.

Kontaridis MI, Eminaga S, Fornaro M, Zito CI, Sordella R, Settleman J, Bennett AM.

Mol Cell Biol. 2004 Jun;24(12):5340-52.


Aberrant activation of atypical protein kinase C in carbon tetrachloride-induced oxidative stress provokes a disturbance of cell polarity and sealing of bile canalicular lumen.

Horikoshi Y, Kitatani K, Toriumi K, Fukunishi N, Itoh Y, Nakamura N, Ohno S, Matsura T, Takekoshi S.

Am J Pathol. 2015 Apr;185(4):958-68. doi: 10.1016/j.ajpath.2014.12.015. Epub 2015 Feb 14.


A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.

Wang L, Yang L, Luo Y, Zheng Y.

J Biol Chem. 2003 Nov 7;278(45):44617-25. Epub 2003 Aug 25.


aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity.

Suzuki A, Hirata M, Kamimura K, Maniwa R, Yamanaka T, Mizuno K, Kishikawa M, Hirose H, Amano Y, Izumi N, Miwa Y, Ohno S.

Curr Biol. 2004 Aug 24;14(16):1425-35.


The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development.

Brouns MR, Matheson SF, Hu KQ, Delalle I, Caviness VS, Silver J, Bronson RT, Settleman J.

Development. 2000 Nov;127(22):4891-903.


Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.

Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K.

Nat Cell Biol. 2004 Apr;6(4):328-34. Epub 2004 Mar 28.


Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells.

Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, Yonemura S, Ohno S.

J Cell Sci. 2009 May 15;122(Pt 10):1595-606. doi: 10.1242/jcs.043174. Epub 2009 Apr 28.


Kinase-activity-independent functions of atypical protein kinase C in Drosophila.

Kim S, Gailite I, Moussian B, Luschnig S, Goette M, Fricke K, Honemann-Capito M, Grubmüller H, Wodarz A.

J Cell Sci. 2009 Oct 15;122(Pt 20):3759-71. doi: 10.1242/jcs.052514. Epub 2009 Sep 29.


Rho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Rac1) GTPase-activating protein that controls dendritic spine morphogenesis.

Raynaud F, Moutin E, Schmidt S, Dahl J, Bertaso F, Boeckers TM, Homburger V, Fagni L.

J Biol Chem. 2014 Jan 31;289(5):2600-9. doi: 10.1074/jbc.M113.534636. Epub 2013 Dec 18.


The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines.

Saneyoshi T, Hayashi Y.

Cytoskeleton (Hoboken). 2012 Aug;69(8):545-54. doi: 10.1002/cm.21037. Epub 2012 May 22. Review.


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