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Items: 13

1.

Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons.

Wang D, Tang B, Zhao G, Pan Q, Xia K, Bodmer R, Zhang Z.

Mol Neurodegener. 2008 Feb 8;3:3. doi: 10.1186/1750-1326-3-3.

2.

LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin.

Yang D, Li T, Liu Z, Arbez N, Yan J, Moran TH, Ross CA, Smith WW.

Neurobiol Dis. 2012 Sep;47(3):385-92. doi: 10.1016/j.nbd.2012.05.020.

PMID:
22668778
3.

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.

Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, Pallanck LJ, Bonini NM.

Curr Biol. 2005 Sep 6;15(17):1572-7.

4.

Knockdown transgenic Lrrk Drosophila resists paraquat-induced locomotor impairment and neurodegeneration: A therapeutic strategy for Parkinson's disease.

Quintero-Espinosa D, Jimenez-Del-Rio M, Velez-Pardo C.

Brain Res. 2017 Feb 15;1657:253-261. doi: 10.1016/j.brainres.2016.12.023.

PMID:
28041945
5.

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.

Lee SB, Kim W, Lee S, Chung J.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):534-9.

PMID:
17498648
6.

Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila.

Kanao T, Venderova K, Park DS, Unterman T, Lu B, Imai Y.

Hum Mol Genet. 2010 Oct 1;19(19):3747-58. doi: 10.1093/hmg/ddq289.

PMID:
20624856
7.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.

Islam MS, Nolte H, Jacob W, Ziegler AB, Pütz S, Grosjean Y, Szczepanowska K, Trifunovic A, Braun T, Heumann H, Heumann R, Hovemann B, Moore DJ, Krüger M.

Hum Mol Genet. 2016 Oct 29. pii: ddw352. doi: 10.1093/hmg/ddw352. [Epub ahead of print]

PMID:
27794539
8.

Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.

Nixon-Abell J, Berwick DC, Grannó S, Spain VA, Blackstone C, Harvey K.

Front Mol Neurosci. 2016 Mar 8;9:18. doi: 10.3389/fnmol.2016.00018.

9.

Classification of Parkinson's Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision.

West RJ, Elliott CJ, Wade AR.

Sci Rep. 2015 Nov 24;5:16933. doi: 10.1038/srep16933.

10.

Interaction of LRRK2 with kinase and GTPase signaling cascades.

Boon JY, Dusonchet J, Trengrove C, Wolozin B.

Front Mol Neurosci. 2014 Jul 9;7:64. doi: 10.3389/fnmol.2014.00064. Review.

11.

Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson's disease model.

Ortega-Arellano HF, Jimenez-Del-Rio M, Velez-Pardo C.

Genet Mol Biol. 2013 Dec;36(4):608-15. doi: 10.1590/S1415-47572013000400020.

12.

Drosophila Mutant Model of Parkinson's Disease Revealed an Unexpected Olfactory Performance: Morphofunctional Evidences.

De Rose F, Corda V, Solari P, Sacchetti P, Belcari A, Poddighe S, Kasture S, Solla P, Marrosu F, Liscia A.

Parkinsons Dis. 2016;2016:3508073. doi: 10.1155/2016/3508073.

13.

LRRK2(I2020T) Functional Genetic Interactors that Modify Eye Degeneration and Dopaminergic Cell Loss in Drosophila.

Marcogliese PC, Abuaish S, Kabbach G, Abdel-Messih E, Seang S, Li G, Slack RS, Emdadul Haque M, Venderova K, Park DS.

Hum Mol Genet. 2017 Feb 2. doi: 10.1093/hmg/ddx030. [Epub ahead of print] No abstract available.

PMID:
28158614

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