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Items: 1 to 20 of 132

1.

A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts.

Casso DJ, Liu S, Iwaki DD, Ogden SK, Kornberg TB.

Genetics. 2008 Mar;178(3):1399-413. doi: 10.1534/genetics.107.081638. Epub 2008 Feb 3.

2.

In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signaling.

Du J, Zhang J, Su Y, Liu M, Ospina JK, Yang S, Zhu AJ.

PLoS One. 2011;6(9):e24168. doi: 10.1371/journal.pone.0024168. Epub 2011 Sep 8.

3.

Identification and Validation of Novel Hedgehog-Responsive Enhancers Predicted by Computational Analysis of Ci/Gli Binding Site Density.

Gurdziel K, Lorberbaum DS, Udager AM, Song JY, Richards N, Parker DS, Johnson LA, Allen BL, Barolo S, Gumucio DL.

PLoS One. 2015 Dec 28;10(12):e0145225. doi: 10.1371/journal.pone.0145225. eCollection 2015.

4.

A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway.

Collins RT, Cohen SM.

Genetics. 2005 May;170(1):173-84. Epub 2005 Mar 2.

5.

The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.

Carroll CE, Marada S, Stewart DP, Ouyang JX, Ogden SK.

Development. 2012 Feb;139(3):612-21. doi: 10.1242/dev.075614. Erratum in: Development. 2012 Feb;139(4):827.

6.

Control of antagonistic components of the hedgehog signaling pathway by microRNAs in Drosophila.

Friggi-Grelin F, Lavenant-Staccini L, Therond P.

Genetics. 2008 May;179(1):429-39. doi: 10.1534/genetics.107.083733.

7.

Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila.

Jiang K, Liu Y, Fan J, Epperly G, Gao T, Jiang J, Jia J.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4842-50. doi: 10.1073/pnas.1417147111. Epub 2014 Oct 27.

8.

Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.

Ruel L, Gallet A, Raisin S, Truchi A, Staccini-Lavenant L, Cervantes A, Thérond PP.

Development. 2007 Oct;134(20):3677-89. Epub 2007 Sep 19.

9.

Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction.

Shi D, Lv X, Zhang Z, Yang X, Zhou Z, Zhang L, Zhao Y.

J Biol Chem. 2013 May 3;288(18):12605-14. doi: 10.1074/jbc.M112.399477. Epub 2013 Mar 26.

10.

The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control.

Mosimann C, Hausmann G, Basler K.

Mech Dev. 2009 May-Jun;126(5-6):394-405. doi: 10.1016/j.mod.2009.02.002. Epub 2009 Feb 11.

11.

PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation.

Jia H, Liu Y, Yan W, Jia J.

Development. 2009 Jan;136(2):307-16. doi: 10.1242/dev.030015. Epub 2008 Dec 15.

12.

HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogaster.

Deshpande G, Schedl P.

Dev Cell. 2005 Nov;9(5):629-38.

13.

Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions.

Ogawa H, Ohta N, Moon W, Matsuzaki F.

J Cell Sci. 2009 Sep 15;122(Pt 18):3242-9. doi: 10.1242/jcs.050955. Epub 2009 Aug 18.

14.

Analysis of the transcriptomes downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch signaling pathways in Drosophila melanogaster.

Nfonsam LE, Cano C, Mudge J, Schilkey FD, Curtiss J.

PLoS One. 2012;7(8):e44583. doi: 10.1371/journal.pone.0044583. Epub 2012 Aug 31.

15.
16.

Cilia-mediated hedgehog signaling in Drosophila.

Kuzhandaivel A, Schultz SW, Alkhori L, Alenius M.

Cell Rep. 2014 May 8;7(3):672-80. doi: 10.1016/j.celrep.2014.03.052. Epub 2014 Apr 24.

17.

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway.

Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N.

Nat Genet. 2005 Dec;37(12):1323-32. Epub 2005 Nov 20.

PMID:
16311596
19.

Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction.

Apionishev S, Katanayeva NM, Marks SA, Kalderon D, Tomlinson A.

Nat Cell Biol. 2005 Jan;7(1):86-92. Epub 2004 Dec 12.

PMID:
15592457
20.

Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover.

Huang S, Zhang Z, Zhang C, Lv X, Zheng X, Chen Z, Sun L, Wang H, Zhu Y, Zhang J, Yang S, Lu Y, Sun Q, Tao Y, Liu F, Zhao Y, Chen D.

PLoS Biol. 2013 Nov;11(11):e1001721. doi: 10.1371/journal.pbio.1001721. Epub 2013 Nov 26.

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