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Items: 1 to 20 of 84

1.

Clustering of genetically defined allele classes in the Caenorhabditis elegans DAF-2 insulin/IGF-1 receptor.

Patel DS, Garza-Garcia A, Nanji M, McElwee JJ, Ackerman D, Driscoll PC, Gems D.

Genetics. 2008 Feb;178(2):931-46. doi: 10.1534/genetics.107.070813. Epub 2008 Feb 1.

2.

Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.

Gems D, Sutton AJ, Sundermeyer ML, Albert PS, King KV, Edgley ML, Larsen PL, Riddle DL.

Genetics. 1998 Sep;150(1):129-55.

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pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans.

Monje JM, Brokate-Llanos AM, Pérez-Jiménez MM, Fidalgo MA, Muñoz MJ.

Aging Cell. 2011 Dec;10(6):1021-31. doi: 10.1111/j.1474-9726.2011.00747.x.

6.

DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.

Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM, Gems D.

PLoS Genet. 2014 Feb 6;10(2):e1004109. doi: 10.1371/journal.pgen.1004109. eCollection 2014 Feb.

7.

LC-MS proteomics analysis of the insulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism.

Depuydt G, Xie F, Petyuk VA, Smolders A, Brewer HM, Camp DG 2nd, Smith RD, Braeckman BP.

J Proteome Res. 2014 Apr 4;13(4):1938-56. doi: 10.1021/pr401081b. Epub 2014 Mar 3.

8.

Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity.

Zhang Y, Xu J, Puscau C, Kim Y, Wang X, Alam H, Hu PJ.

Dev Biol. 2008 Mar 15;315(2):290-302. doi: 10.1016/j.ydbio.2007.12.032. Epub 2008 Jan 3.

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Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans.

Liu T, Zimmerman KK, Patterson GI.

BMC Dev Biol. 2004 Sep 20;4:11.

12.

Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance.

McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D.

J Biol Chem. 2004 Oct 22;279(43):44533-43. Epub 2004 Aug 11.

13.

Divergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway.

Mabon ME, Scott BA, Crowder CM.

PLoS One. 2009 Nov 20;4(11):e7937. doi: 10.1371/journal.pone.0007937.

14.

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.

Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G.

Science. 1997 Aug 15;277(5328):942-6.

15.

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene.

Gil EB, Malone Link E, Liu LX, Johnson CD, Lees JA.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2925-30.

16.

Regulation of aging and age-related disease by DAF-16 and heat-shock factor.

Hsu AL, Murphy CT, Kenyon C.

Science. 2003 May 16;300(5622):1142-5. Erratum in: Science. 2003 Jun 27;300(5628):2033.

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Caenorhabditis elegans SDF-9 enhances insulin/insulin-like signaling through interaction with DAF-2.

Jensen VL, Albert PS, Riddle DL.

Genetics. 2007 Sep;177(1):661-6. Epub 2007 Jul 29.

19.

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.

Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G.

Nature. 1997 Oct 30;389(6654):994-9.

PMID:
9353126
20.

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