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Items: 1 to 20 of 111

1.

Architectural changes in the thymus of aging mice.

Aw D, Silva AB, Maddick M, von Zglinicki T, Palmer DB.

Aging Cell. 2008 Mar;7(2):158-67. doi: 10.1111/j.1474-9726.2007.00365.x. Epub 2008 Jan 28.

2.

Phenotypical and morphological changes in the thymic microenvironment from ageing mice.

Aw D, Taylor-Brown F, Cooper K, Palmer DB.

Biogerontology. 2009 Jun;10(3):311-22. doi: 10.1007/s10522-008-9182-2. Epub 2008 Oct 18.

PMID:
18931936
3.

Involution of the mammalian thymus, one of the leading regulators of aging.

Bodey B, Bodey B Jr, Siegel SE, Kaiser HE.

In Vivo. 1997 Sep-Oct;11(5):421-40.

PMID:
9427047
4.

The role of zinc in pre- and postnatal mammalian thymic immunohistogenesis.

Bodey B, Bodey B Jr, Siegel SE, Kaiser HE.

In Vivo. 1998 Nov-Dec;12(6):695-722.

PMID:
9891234
5.

Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity.

Youm YH, Yang H, Sun Y, Smith RG, Manley NR, Vandanmagsar B, Dixit VD.

J Biol Chem. 2009 Mar 13;284(11):7068-77. doi: 10.1074/jbc.M808302200. Epub 2008 Dec 2.

6.

Premature thymic involution is independent of structural plasticity of the thymic stroma.

Franckaert D, Schlenner SM, Heirman N, Gill J, Skogberg G, Ekwall O, Put K, Linterman MA, Dooley J, Liston A.

Eur J Immunol. 2015 May;45(5):1535-47. doi: 10.1002/eji.201445277. Epub 2015 Feb 23.

7.

Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence.

Kvell K, Varecza Z, Bartis D, Hesse S, Parnell S, Anderson G, Jenkinson EJ, Pongracz JE.

PLoS One. 2010 May 18;5(5):e10701. doi: 10.1371/journal.pone.0010701.

8.

Meis1 is required for the maintenance of postnatal thymic epithelial cells.

Hirayama T, Asano Y, Iida H, Watanabe T, Nakamura T, Goitsuka R.

PLoS One. 2014 Mar 4;9(3):e89885. doi: 10.1371/journal.pone.0089885. eCollection 2014.

9.

Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution.

Sun L, Guo J, Brown R, Amagai T, Zhao Y, Su DM.

Aging Cell. 2010 Jun;9(3):347-57. doi: 10.1111/j.1474-9726.2010.00559.x. Epub 2010 Mar 12.

10.

Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution.

Gruver AL, Ventevogel MS, Sempowski GD.

J Endocrinol. 2009 Oct;203(1):75-85. doi: 10.1677/JOE-09-0179. Epub 2009 Jul 8.

11.

The murine thymic microenvironment: changes with age.

Takeoka Y, Chen SY, Yago H, Boyd R, Suehiro S, Shultz LD, Ansari AA, Gershwin ME.

Int Arch Allergy Immunol. 1996 Sep;111(1):5-12.

PMID:
8753837
12.

The aged thymus shows normal recruitment of lymphohematopoietic progenitors but has defects in thymic epithelial cells.

Gui J, Zhu X, Dohkan J, Cheng L, Barnes PF, Su DM.

Int Immunol. 2007 Oct;19(10):1201-11. Epub 2007 Sep 5.

PMID:
17804689
13.

TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution.

Hauri-Hohl MM, Zuklys S, Keller MP, Jeker LT, Barthlott T, Moon AM, Roes J, Holländer GA.

Blood. 2008 Aug 1;112(3):626-34. doi: 10.1182/blood-2007-10-115618. Epub 2008 May 12.

14.

An epithelial progenitor pool regulates thymus growth.

Jenkinson WE, Bacon A, White AJ, Anderson G, Jenkinson EJ.

J Immunol. 2008 Nov 1;181(9):6101-8.

15.

Transcriptome analysis of murine thymic epithelial cells reveals age‑associated changes in microRNA expression.

Guo Z, Chi F, Song Y, Wang C, Yu R, Wei T, Gui J, Zhu X.

Int J Mol Med. 2013 Oct;32(4):835-42. doi: 10.3892/ijmm.2013.1471. Epub 2013 Aug 21.

PMID:
23969555
16.

Regeneration of the aged thymus by a single transcription factor.

Bredenkamp N, Nowell CS, Blackburn CC.

Development. 2014 Apr;141(8):1627-37. doi: 10.1242/dev.103614.

17.
18.

Wnt4 signaling is associated with the decrease of proliferation and increase of apoptosis during age-related thymic involution.

Wei T, Zhang N, Guo Z, Chi F, Song Y, Zhu X.

Mol Med Rep. 2015 Nov;12(5):7568-76. doi: 10.3892/mmr.2015.4343. Epub 2015 Sep 21.

PMID:
26397044
19.

Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling.

Yang H, Youm YH, Sun Y, Rim JS, Galbán CJ, Vandanmagsar B, Dixit VD.

J Leukoc Biol. 2009 Jun;85(6):928-38. doi: 10.1189/jlb.1008621.

20.

Lymphohematopoietic progenitors do not have a synchronized defect with age-related thymic involution.

Zhu X, Gui J, Dohkan J, Cheng L, Barnes PF, Su DM.

Aging Cell. 2007 Oct;6(5):663-72. Epub 2007 Aug 6.

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