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Items: 1 to 20 of 266


Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton.

Shifley ET, Vanhorn KM, Perez-Balaguer A, Franklin JD, Weinstein M, Cole SE.

Development. 2008 Mar;135(5):899-908. doi: 10.1242/dev.006742. Epub 2008 Jan 30.


Transcriptional oscillation of lunatic fringe is essential for somitogenesis.

Serth K, Schuster-Gossler K, Cordes R, Gossler A.

Genes Dev. 2003 Apr 1;17(7):912-25.


Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis.

Williams DR, Shifley ET, Lather JD, Cole SE.

Dev Biol. 2014 Apr 15;388(2):159-69. doi: 10.1016/j.ydbio.2014.02.006. Epub 2014 Feb 19.


The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.

Oginuma M, Takahashi Y, Kitajima S, Kiso M, Kanno J, Kimura A, Saga Y.

Development. 2010 May;137(9):1515-22. doi: 10.1242/dev.044545. Epub 2010 Mar 24.


Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock.

Dale JK, Maroto M, Dequeant ML, Malapert P, McGrew M, Pourquie O.

Nature. 2003 Jan 16;421(6920):275-8. Epub 2003 Jan 12.


Defects in somite formation in lunatic fringe-deficient mice.

Zhang N, Gridley T.

Nature. 1998 Jul 23;394(6691):374-7.


Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.

Feller J, Schneider A, Schuster-Gossler K, Gossler A.

Genes Dev. 2008 Aug 15;22(16):2166-71. doi: 10.1101/gad.480408.


Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion.

Williams DR, Shifley ET, Braunreiter KM, Cole SE.

Development. 2016 Mar 1;143(5):822-30. doi: 10.1242/dev.128538. Epub 2016 Jan 25.


Oscillator mechanism of Notch pathway in the segmentation clock.

Kageyama R, Masamizu Y, Niwa Y.

Dev Dyn. 2007 Jun;236(6):1403-9. Review.


lunatic fringe is an essential mediator of somite segmentation and patterning.

Evrard YA, Lun Y, Aulehla A, Gan L, Johnson RL.

Nature. 1998 Jul 23;394(6691):377-81.


The role of presenilin 1 during somite segmentation.

Koizumi K, Nakajima M, Yuasa S, Saga Y, Sakai T, Kuriyama T, Shirasawa T, Koseki H.

Development. 2001 Apr;128(8):1391-402.


Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.

Stauber M, Sachidanandan C, Morgenstern C, Ish-Horowicz D.

PLoS One. 2009 Nov 24;4(11):e7996. doi: 10.1371/journal.pone.0007996.


Specification of vertebral identity is coupled to Notch signalling and the segmentation clock.

Cordes R, Schuster-Gossler K, Serth K, Gossler A.

Development. 2004 Mar;131(6):1221-33. Epub 2004 Feb 11.


Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock.

Shankaran SS, Sieger D, Schröter C, Czepe C, Pauly MC, Laplante MA, Becker TS, Oates AC, Gajewski M.

Dev Biol. 2007 Apr 15;304(2):615-32. Epub 2007 Jan 9.


Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock.

Shifley ET, Cole SE.

Biochim Biophys Acta. 2008 Dec;1783(12):2384-90. doi: 10.1016/j.bbamcr.2008.07.009. Epub 2008 Jul 25.


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