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Items: 1 to 20 of 106

1.

The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement.

Engel SR, Creson TK, Hao Y, Shen Y, Maeng S, Nekrasova T, Landreth GE, Manji HK, Chen G.

Mol Psychiatry. 2009 Apr;14(4):448-61. doi: 10.1038/sj.mp.4002135. Epub 2008 Jan 29.

2.

The anterior cingulate ERK pathway contributes to regulation of behavioral excitement and hedonic activity.

Creson TK, Hao Y, Engel S, Shen Y, Hamidi A, Zhuo M, Manji HK, Chen G.

Bipolar Disord. 2009 Jun;11(4):339-50. doi: 10.1111/j.1399-5618.2009.00697.x.

PMID:
19500087
3.

The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

Einat H, Yuan P, Gould TD, Li J, Du J, Zhang L, Manji HK, Chen G.

J Neurosci. 2003 Aug 13;23(19):7311-6.

4.

Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P, Gould TD, Manji HK, Chen G.

J Neurosci. 2004 Jul 21;24(29):6590-9.

5.

The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers.

Chen G, Manji HK.

Curr Opin Psychiatry. 2006 May;19(3):313-23. Review.

PMID:
16612219
6.

Lithium treatment attenuates muscarinic M(1) receptor dysfunction.

Creson TK, Austin DR, Shaltiel G, McCammon J, Wess J, Manji HK, Chen G.

Bipolar Disord. 2011 May;13(3):238-49. doi: 10.1111/j.1399-5618.2011.00915.x.

PMID:
21676127
7.

Clozapine regulation of p90RSK and c-Fos signaling via the ErbB1-ERK pathway is distinct from olanzapine and haloperidol in mouse cortex and striatum.

Pereira A, Zhang B, Malcolm P, Sundram S.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:353-63. doi: 10.1016/j.pnpbp.2012.10.025. Epub 2012 Nov 8.

PMID:
23142770
8.

Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice.

Einat H, Manji HK, Gould TD, Du J, Chen G.

Drug News Perspect. 2003 Sep;16(7):453-63. Review.

PMID:
14668941
9.

Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice.

Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG.

J Biol Chem. 2006 Oct 27;281(43):32072-80. Epub 2006 Sep 5.

10.

Regulatory mechanisms of fear extinction and depression-like behavior.

Tronson NC, Schrick C, Fischer A, Sananbenesi F, Pagès G, Pouysségur J, Radulovic J.

Neuropsychopharmacology. 2008 Jun;33(7):1570-83. Epub 2007 Aug 22.

11.

Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice.

Todorovic C, Sherrin T, Pitts M, Hippel C, Rayner M, Spiess J.

Neuropsychopharmacology. 2009 May;34(6):1416-26. doi: 10.1038/npp.2008.178. Epub 2008 Oct 8.

12.

Lack of lithium-like behavioral and molecular effects in IMPA2 knockout mice.

Cryns K, Shamir A, Shapiro J, Daneels G, Goris I, Van Craenendonck H, Straetemans R, Belmaker RH, Agam G, Moechars D, Steckler T.

Neuropsychopharmacology. 2007 Apr;32(4):881-91. Epub 2006 Jul 12.

13.

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania.

Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK.

Mol Psychiatry. 2008 Sep;13(9):858-72. doi: 10.1038/mp.2008.20. Epub 2008 Mar 11.

14.

Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate.

Creson TK, Yuan P, Manji HK, Chen G.

J Mol Neurosci. 2009 Feb;37(2):123-34. doi: 10.1007/s12031-008-9122-2. Epub 2008 Aug 3.

15.

Dose-dependent effect of intracerebroventricular injection of ouabain on the phosphorylation of the MEK1/2-ERK1/2-p90RSK pathway in the rat brain related to locomotor activity.

Kim SH, Yu HS, Park HG, Jeon WJ, Song JY, Kang UG, Ahn YM, Lee YH, Kim YS.

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Oct 1;32(7):1637-42. doi: 10.1016/j.pnpbp.2008.05.027. Epub 2008 Jun 8.

PMID:
18590792
16.

Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress.

Iñiguez SD, Vialou V, Warren BL, Cao JL, Alcantara LF, Davis LC, Manojlovic Z, Neve RL, Russo SJ, Han MH, Nestler EJ, Bolaños-Guzmán CA.

J Neurosci. 2010 Jun 2;30(22):7652-63. doi: 10.1523/JNEUROSCI.0951-10.2010.

17.

Role of extracellular signal-regulated kinase signal transduction pathway in anxiety.

Ailing F, Fan L, Li S, Manji S.

J Psychiatr Res. 2008 Nov;43(1):55-63. doi: 10.1016/j.jpsychires.2008.01.018. Epub 2008 Mar 17.

PMID:
18348889
18.

Valproic acid enhances protein L-isoaspartyl methyltransferase expression by stimulating extracellular signal-regulated kinase signaling pathway.

Cournoyer P, Desrosiers RR.

Neuropharmacology. 2009 Apr;56(5):839-48. doi: 10.1016/j.neuropharm.2009.01.008. Epub 2009 Jan 19.

PMID:
19371592
19.

Haloperidol regulates the phosphorylation level of the MEK-ERK-p90RSK signal pathway via protein phosphatase 2A in the rat frontal cortex.

Kim SH, Seo MS, Jeon WJ, Yu HS, Park HG, Jung GA, Lee HY, Kang UG, Kim YS.

Int J Neuropsychopharmacol. 2008 Jun;11(4):509-17. doi: 10.1017/S1461145707008292. Epub 2008 Jan 16.

PMID:
18272021
20.

Cellular plasticity cascades: genes-to-behavior pathways in animal models of bipolar disorder.

Einat H, Manji HK.

Biol Psychiatry. 2006 Jun 15;59(12):1160-71. Epub 2006 Feb 2. Review.

PMID:
16457783

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