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Items: 1 to 20 of 91

1.

A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose.

Tash JS, Attardi B, Hild SA, Chakrasali R, Jakkaraj SR, Georg GI.

Biol Reprod. 2008 Jun;78(6):1127-38. doi: 10.1095/biolreprod.106.057810. Epub 2008 Jan 23.

PMID:
18218612
2.

Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat Sertoli cells.

Tash JS, Chakrasali R, Jakkaraj SR, Hughes J, Smith SK, Hornbaker K, Heckert LL, Ozturk SB, Hadden MK, Kinzy TG, Blagg BS, Georg GI.

Biol Reprod. 2008 Jun;78(6):1139-52. doi: 10.1095/biolreprod.107.062679. Epub 2008 Jan 23.

PMID:
18218611
3.
4.

Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis.

Cheng CY, Silvestrini B, Grima J, Mo MY, Zhu LJ, Johansson E, Saso L, Leone MG, Palmery M, Mruk D.

Biol Reprod. 2001 Aug;65(2):449-61.

PMID:
11466213
5.

Effect of chronic administration of an aromatase inhibitor to adult male rats on pituitary and testicular function and fertility.

Turner KJ, Morley M, Atanassova N, Swanston ID, Sharpe RM.

J Endocrinol. 2000 Feb;164(2):225-38.

7.
8.

Efficacy trial on the purified compounds of the seeds of Carica papaya for male contraception in albino rat.

Lohiya NK, Mishra PK, Pathak N, Manivannan B, Bhande SS, Panneerdoss S, Sriram S.

Reprod Toxicol. 2005 May-Jun;20(1):135-48.

PMID:
15808797
9.
10.

Indazole carboxylic acids in male contraception.

Cheng CY, Mo My, Grima J, Saso L, Tita B, Mruk D, Silvestrini B.

Contraception. 2002 Apr;65(4):265-8. Review.

PMID:
12020774
11.

Disruption of spermatogenesis and Sertoli cell structure and function by the indenopyridine CDB-4022 in rats.

Hild SA, Reel JR, Larner JM, Blye RP.

Biol Reprod. 2001 Dec;65(6):1771-9.

PMID:
11717140
14.
15.

Prolonged administration of proguanil induces reproductive toxicity in male rats.

Stephen AO, Yinusa R.

J Toxicol Sci. 2011 Oct;36(5):587-99.

17.

Effects of long-term cocaine exposure on spermatogenesis and fertility in peripubertal male rats.

George VK, Li H, Teloken C, Grignon DJ, Lawrence WD, Dhabuwala CB.

J Urol. 1996 Jan;155(1):327-31.

PMID:
7490880
18.

Long-term effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats.

Huynh PN, Hikim AP, Wang C, Stefonovic K, Lue YH, Leung A, Atienza V, Baravarian S, Reutrakul V, Swerdloff RS.

J Androl. 2000 Sep-Oct;21(5):689-99.

20.

Potential parameters of male reproductive toxicity: reproductive performance, histopathology and sperm evaluation in SD rats given nitrazepam.

Kishi K, Kanamori S, Maruyama T, Sasaki K, Hara K, Kawai M, Ikeuchi K.

J Toxicol Sci. 1995 Aug;20(3):329-39.

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