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Items: 1 to 20 of 59

1.

Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn.

Tzika AA, Mintzopoulos D, Padfield K, Wilhelmy J, Mindrinos MN, Yu H, Cao H, Zhang Q, Astrakas LG, Zhang J, Yu YM, Rahme LG, Tompkins RG.

Int J Mol Med. 2008 Feb;21(2):201-8.

PMID:
18204786
2.

Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma.

Tzika AA, Astrakas LG, Cao H, Mintzopoulos D, Zhang Q, Padfield K, Yu H, Mindrinos MN, Rahme LG, Tompkins RG.

Int J Mol Med. 2008 Jun;21(6):825-32.

PMID:
18506378
3.

Burn injury causes mitochondrial dysfunction in skeletal muscle.

Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5368-73. Epub 2005 Apr 4.

4.

Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy.

Righi V, Constantinou C, Mintzopoulos D, Khan N, Mupparaju SP, Rahme LG, Swartz HM, Szeto HH, Tompkins RG, Tzika AA.

FASEB J. 2013 Jun;27(6):2521-30. doi: 10.1096/fj.12-220764. Epub 2013 Mar 12.

5.

Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.

Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG.

Int J Mol Med. 2009 Sep;24(3):387-92.

6.

Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia.

Constantinou C, Fontes de Oliveira CC, Mintzopoulos D, Busquets S, He J, Kesarwani M, Mindrinos M, Rahme LG, Argilés JM, Tzika AA.

Int J Mol Med. 2011 Jan;27(1):15-24. doi: 10.3892/ijmm.2010.557. Epub 2010 Nov 10.

7.

PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.

Sonoda J, Mehl IR, Chong LW, Nofsinger RR, Evans RM.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5223-8. Epub 2007 Mar 12.

8.

Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis.

Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA.

FASEB J. 2005 Sep;19(11):1431-40.

PMID:
16126910
9.

Overexpression of peroxisome proliferator-activated receptor gamma co-activator-1alpha leads to muscle atrophy with depletion of ATP.

Miura S, Tomitsuka E, Kamei Y, Yamazaki T, Kai Y, Tamura M, Kita K, Nishino I, Ezaki O.

Am J Pathol. 2006 Oct;169(4):1129-39.

10.

Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation.

Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, Spiegelman BM.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4721-6. doi: 10.1073/pnas.0800979105. Epub 2008 Mar 17.

11.

Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

Jørgensen SB, Wojtaszewski JF, Viollet B, Andreelli F, Birk JB, Hellsten Y, Schjerling P, Vaulont S, Neufer PD, Richter EA, Pilegaard H.

FASEB J. 2005 Jul;19(9):1146-8. Epub 2005 May 5.

PMID:
15878932
12.

Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance.

Vianna CR, Huntgeburth M, Coppari R, Choi CS, Lin J, Krauss S, Barbatelli G, Tzameli I, Kim YB, Cinti S, Shulman GI, Spiegelman BM, Lowell BB.

Cell Metab. 2006 Dec;4(6):453-64.

13.

An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation.

Miura S, Kawanaka K, Kai Y, Tamura M, Goto M, Shiuchi T, Minokoshi Y, Ezaki O.

Endocrinology. 2007 Jul;148(7):3441-8. Epub 2007 Apr 19.

PMID:
17446185
14.

Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway.

Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB, Williams RS, Yan Z.

J Biol Chem. 2005 May 20;280(20):19587-93. Epub 2005 Mar 14.

15.

Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.

Wu Z, Huang X, Feng Y, Handschin C, Feng Y, Gullicksen PS, Bare O, Labow M, Spiegelman B, Stevenson SC.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14379-84. Epub 2006 Sep 15.

16.

Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha.

Cha SH, Rodgers JT, Puigserver P, Chohnan S, Lane MD.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15410-5. Epub 2006 Oct 9.

17.

PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.

Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.

FASEB J. 2005 Dec;19(14):2072-4. Epub 2005 Oct 3. Retraction in: FASEB J. 2009 Aug;23(8):2790.

PMID:
16203862
18.

Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma.

Ogunbileje JO, Porter C, Herndon DN, Chao T, Abdelrahman DR, Papadimitriou A, Chondronikola M, Zimmers TA, Reidy PT, Rasmussen BB, Sidossis LS.

Am J Physiol Endocrinol Metab. 2016 Aug 1;311(2):E436-48. doi: 10.1152/ajpendo.00535.2015. Epub 2016 Jul 5.

20.

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.

Arany Z, He H, Lin J, Hoyer K, Handschin C, Toka O, Ahmad F, Matsui T, Chin S, Wu PH, Rybkin II, Shelton JM, Manieri M, Cinti S, Schoen FJ, Bassel-Duby R, Rosenzweig A, Ingwall JS, Spiegelman BM.

Cell Metab. 2005 Apr;1(4):259-71.

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