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Items: 1 to 20 of 77

1.

Individual heterogeneity in platelet response to lysophosphatidic acid: evidence for a novel inhibitory pathway.

Pamuklar Z, Lee JS, Cheng HY, Panchatcharam M, Steinhubl S, Morris AJ, Charnigo R, Smyth SS.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):555-61. doi: 10.1161/ATVBAHA.107.151837. Epub 2008 Jan 17.

2.

The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors.

Haserück N, Erl W, Pandey D, Tigyi G, Ohlmann P, Ravanat C, Gachet C, Siess W.

Blood. 2004 Apr 1;103(7):2585-92. Epub 2003 Nov 26.

3.

Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques.

Rother E, Brandl R, Baker DL, Goyal P, Gebhard H, Tigyi G, Siess W.

Circulation. 2003 Aug 12;108(6):741-7. Epub 2003 Jul 28.

4.

Lysophosphatidic acid-induced platelet shape change revealed through LPA(1-5) receptor-selective probes and albumin.

Khandoga AL, Fujiwara Y, Goyal P, Pandey D, Tsukahara R, Bolen A, Guo H, Wilke N, Liu J, Valentine WJ, Durgam GG, Miller DD, Jiang G, Prestwich GD, Tigyi G, Siess W.

Platelets. 2008 Sep;19(6):415-27. doi: 10.1080/09537100802220468.

5.

Lysophosphatidic acid is the unique platelet-activating substance in human malignant ascites.

Sandmann G, Siess W, Essler M.

Eur J Med Res. 2003 Sep 29;8(9):397-404.

PMID:
14555295
6.

Synergistic activation of human platelets by lysophosphatidic acid and adrenaline.

Nilsson U, Svensson SP, Grenegård M.

Haematologica. 2002 Jul;87(7):730-9; discussion 739.

7.

Thrombogenic and atherogenic activities of lysophosphatidic acid.

Siess W, Tigyi G.

J Cell Biochem. 2004 Aug 15;92(6):1086-94. Review.

PMID:
15258894
8.
9.

Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids.

Tokumura A, Sinomiya J, Kishimoto S, Tanaka T, Kogure K, Sugiura T, Satouchi K, Waku K, Fukuzawa K.

Biochem J. 2002 Aug 1;365(Pt 3):617-28.

10.

The influence of lysophosphatidic acid on platelet protein phosphorylation.

Gerrard JM, Beattie LL, McCrae JM, Singhroy S.

Biochem Cell Biol. 1987 Jul;65(7):642-50.

PMID:
3435662
11.

Structure-activity analysis of the effects of lysophosphatidic acid on platelet aggregation.

Gueguen G, Gaigé B, Grévy JM, Rogalle P, Bellan J, Wilson M, Klaébé A, Pont F, Simon MF, Chap H.

Biochemistry. 1999 Jun 29;38(26):8440-50.

PMID:
10387090
12.

Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity.

Smyth SS, Sciorra VA, Sigal YJ, Pamuklar Z, Wang Z, Xu Y, Prestwich GD, Morris AJ.

J Biol Chem. 2003 Oct 31;278(44):43214-23. Epub 2003 Aug 8.

13.

Selective non-lipid modulator of LPA5 activity in human platelets.

Kozian DH, Evers A, Florian P, Wonerow P, Joho S, Nazare M.

Bioorg Med Chem Lett. 2012 Aug 15;22(16):5239-43. doi: 10.1016/j.bmcl.2012.06.057. Epub 2012 Jun 27.

PMID:
22801643
14.

GPR92/LPA₅ lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques.

Khandoga AL, Pandey D, Welsch U, Brandl R, Siess W.

Cardiovasc Res. 2011 Apr 1;90(1):157-64. doi: 10.1093/cvr/cvq369. Epub 2010 Nov 23.

15.
16.

Increased phosphatidic acid and decreased lysophosphatidic acid in response to thrombin is associated with inhibition of platelet aggregation.

Gerrard JM, Robinson P, Narvey M, McNicol A.

Biochem Cell Biol. 1993 Sep-Oct;71(9-10):432-9.

PMID:
8192895
17.
18.

Pennogenin tetraglycoside stimulates secretion-dependent activation of rat platelets: evidence for critical roles of adenosine diphosphate receptor signal pathways.

Cong Y, Liu X, Kang L, Yu Z, Zhao Z, Li J, Ma B, Cong Y.

Thromb Res. 2012 May;129(5):e209-16. doi: 10.1016/j.thromres.2012.02.001. Epub 2012 Mar 7.

PMID:
22401797
19.

The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

Eichholtz T, Jalink K, Fahrenfort I, Moolenaar WH.

Biochem J. 1993 May 1;291 ( Pt 3):677-80.

20.

Alcohol and platelet function.

Rubin R, Rand ML.

Alcohol Clin Exp Res. 1994 Feb;18(1):105-10. Review.

PMID:
8198204

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