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Items: 1 to 20 of 89

1.

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form.

Serrano-Vega MJ, Magnani F, Shibata Y, Tate CG.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):877-82. doi: 10.1073/pnas.0711253105. Epub 2008 Jan 11.

2.

Engineering an ultra-thermostable β(1)-adrenoceptor.

Miller JL, Tate CG.

J Mol Biol. 2011 Oct 28;413(3):628-38. doi: 10.1016/j.jmb.2011.08.057. Epub 2011 Sep 6.

3.

Transferability of thermostabilizing mutations between beta-adrenergic receptors.

Serrano-Vega MJ, Tate CG.

Mol Membr Biol. 2009 Dec;26(8):385-96. doi: 10.3109/09687680903208239.

PMID:
19883298
4.

Thermostabilization of the β1-adrenergic receptor correlates with increased entropy of the inactive state.

Niesen MJ, Bhattacharya S, Grisshammer R, Tate CG, Vaidehi N.

J Phys Chem B. 2013 Jun 20;117(24):7283-91. doi: 10.1021/jp403207c. Epub 2013 Jun 5.

5.

Structural insights into conformational stability of wild-type and mutant beta1-adrenergic receptor.

Balaraman GS, Bhattacharya S, Vaidehi N.

Biophys J. 2010 Jul 21;99(2):568-77. doi: 10.1016/j.bpj.2010.04.075. Erratum in: Biophys J. 2010 Aug 9;99(4):1329.

6.

The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor.

Baker JG, Proudman RG, Tate CG.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Jul;384(1):71-91. doi: 10.1007/s00210-011-0648-4. Epub 2011 May 6.

7.

Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor.

Magnani F, Shibata Y, Serrano-Vega MJ, Tate CG.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10744-9. doi: 10.1073/pnas.0804396105. Epub 2008 Jul 29.

8.

Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor.

Moukhametzianov R, Warne T, Edwards PC, Serrano-Vega MJ, Leslie AG, Tate CG, Schertler GF.

Proc Natl Acad Sci U S A. 2011 May 17;108(20):8228-32. doi: 10.1073/pnas.1100185108. Epub 2011 May 3.

9.

Prediction of structure and function of G protein-coupled receptors.

Vaidehi N, Floriano WB, Trabanino R, Hall SE, Freddolino P, Choi EJ, Zamanakos G, Goddard WA 3rd.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12622-7. Epub 2002 Sep 26.

10.

Development and crystallization of a minimal thermostabilised G protein-coupled receptor.

Warne T, Serrano-Vega MJ, Tate CG, Schertler GF.

Protein Expr Purif. 2009 Jun;65(2):204-13.

PMID:
19297694
11.

The 2.1 Å resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor.

Miller-Gallacher JL, Nehmé R, Warne T, Edwards PC, Schertler GF, Leslie AG, Tate CG.

PLoS One. 2014 Mar 24;9(3):e92727. doi: 10.1371/journal.pone.0092727. eCollection 2014.

12.

Structure of a beta1-adrenergic G-protein-coupled receptor.

Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, Henderson R, Leslie AG, Tate CG, Schertler GF.

Nature. 2008 Jul 24;454(7203):486-91. doi: 10.1038/nature07101. Epub 2008 Jun 25.

13.

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor.

Isogai S, Deupi X, Opitz C, Heydenreich FM, Tsai CJ, Brueckner F, Schertler GF, Veprintsev DB, Grzesiek S.

Nature. 2016 Feb 11;530(7589):237-41. doi: 10.1038/nature16577. Epub 2016 Feb 3.

PMID:
26840483
14.

Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.

Behr B, Hoffmann C, Ottolina G, Klotz KN.

J Biol Chem. 2006 Jun 30;281(26):18120-5. Epub 2006 Apr 28.

15.

Thermostabilization of the neurotensin receptor NTS1.

Shibata Y, White JF, Serrano-Vega MJ, Magnani F, Aloia AL, Grisshammer R, Tate CG.

J Mol Biol. 2009 Jul 10;390(2):262-77. doi: 10.1016/j.jmb.2009.04.068. Epub 2009 May 5.

16.

Modeling the possible conformations of the extracellular loops in G-protein-coupled receptors.

Nikiforovich GV, Taylor CM, Marshall GR, Baranski TJ.

Proteins. 2010 Feb 1;78(2):271-85. doi: 10.1002/prot.22537.

17.

Functional studies with membrane-bound and detergent-solubilized alpha2-adrenergic receptors expressed in Sf9 cells.

Sen S, Jaakola VP, Pirilä P, Finel M, Goldman A.

Biochim Biophys Acta. 2005 Jun 15;1712(1):62-70. Epub 2005 Apr 26.

18.

Exploring the structure of opioid receptors with homology modeling based on single and multiple templates and subsequent docking: a comparative study.

Bera I, Laskar A, Ghoshal N.

J Mol Model. 2011 May;17(5):1207-21. doi: 10.1007/s00894-010-0803-8. Epub 2010 Jul 27.

PMID:
20661609
19.

Direct molecular evolution of detergent-stable G protein-coupled receptors using polymer encapsulated cells.

Scott DJ, Plückthun A.

J Mol Biol. 2013 Feb 8;425(3):662-77. doi: 10.1016/j.jmb.2012.11.015. Epub 2012 Nov 16.

PMID:
23164568
20.
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