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Items: 1 to 20 of 45

1.

Parkin occurs in a stable, non-covalent, approximately 110-kDa complex in brain.

Van Humbeeck C, Waelkens E, Corti O, Brice A, Vandenberghe W.

Eur J Neurosci. 2008 Jan;27(2):284-93. doi: 10.1111/j.1460-9568.2007.06000.x. Epub 2008 Jan 8.

2.

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels.

Joch M, Ase AR, Chen CX, MacDonald PA, Kontogiannea M, Corera AT, Brice A, Séguéla P, Fon EA.

Mol Biol Cell. 2007 Aug;18(8):3105-18. Epub 2007 Jun 6.

3.

Parkinson's disease: assays for the ubiquitin ligase activity of neural Parkin.

Schlossmacher MG, Shimura H.

Methods Mol Biol. 2005;301:351-69.

PMID:
15917645
4.

Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination.

Lim MK, Kawamura T, Ohsawa Y, Ohtsubo M, Asakawa S, Takayanagi A, Shimizu N.

Exp Cell Res. 2007 Aug 1;313(13):2858-74. Epub 2007 Apr 20.

PMID:
17512523
5.

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

Corti O, Hampe C, Koutnikova H, Darios F, Jacquier S, Prigent A, Robinson JC, Pradier L, Ruberg M, Mirande M, Hirsch E, Rooney T, Fournier A, Brice A.

Hum Mol Genet. 2003 Jun 15;12(12):1427-37.

PMID:
12783850
6.

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity.

Hampe C, Ardila-Osorio H, Fournier M, Brice A, Corti O.

Hum Mol Genet. 2006 Jul 1;15(13):2059-75. Epub 2006 May 19.

PMID:
16714300
7.

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.

Fallon L, Bélanger CM, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, Voortman J, Haber M, Rouleau G, Thorarinsdottir T, Brice A, van Bergen En Henegouwen PM, Fon EA.

Nat Cell Biol. 2006 Aug;8(8):834-42. Epub 2006 Jul 23.

PMID:
16862145
8.

Parkin affects mitochondrial function and apoptosis in neuronal and myogenic cells.

Kuroda Y, Mitsui T, Kunishige M, Matsumoto T.

Biochem Biophys Res Commun. 2006 Sep 29;348(3):787-93. Epub 2006 Aug 4.

PMID:
16905117
9.

Parkin is recruited to the centrosome in response to inhibition of proteasomes.

Zhao J, Ren Y, Jiang Q, Feng J.

J Cell Sci. 2003 Oct 1;116(Pt 19):4011-9. Epub 2003 Aug 19.

10.

[Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease].

Hattori N.

Rinsho Shinkeigaku. 2004 Apr-May;44(4-5):241-62. Review. Japanese.

PMID:
15287506
11.

Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin.

Ardley HC, Scott GB, Rose SA, Tan NG, Markham AF, Robinson PA.

Mol Biol Cell. 2003 Nov;14(11):4541-56. Epub 2003 Aug 22.

12.

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease.

Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ.

Science. 2001 Jul 13;293(5528):263-9. Epub 2001 Jun 28.

13.

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

Ko HS, von Coelln R, Sriram SR, Kim SW, Chung KK, Pletnikova O, Troncoso J, Johnson B, Saffary R, Goh EL, Song H, Park BJ, Kim MJ, Kim S, Dawson VL, Dawson TM.

J Neurosci. 2005 Aug 31;25(35):7968-78.

14.

Parkin expression in the adult mouse brain.

Stichel CC, Augustin M, Kühn K, Zhu XR, Engels P, Ullmer C, Lübbert H.

Eur J Neurosci. 2000 Dec;12(12):4181-94.

PMID:
11122330
15.

Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain.

Fallon L, Moreau F, Croft BG, Labib N, Gu WJ, Fon EA.

J Biol Chem. 2002 Jan 4;277(1):486-91. Epub 2001 Oct 25.

16.

Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.

Pawlyk AC, Giasson BI, Sampathu DM, Perez FA, Lim KL, Dawson VL, Dawson TM, Palmiter RD, Trojanowski JQ, Lee VM.

J Biol Chem. 2003 Nov 28;278(48):48120-8. Epub 2003 Sep 12.

17.

Distribution of parkin in the adult rat brain.

D'Agata V, Zhao W, Pascale A, Zohar O, Scapagnini G, Cavallaro S.

Prog Neuropsychopharmacol Biol Psychiatry. 2002 Apr;26(3):519-27.

PMID:
11999903
18.

Parkin immunoreactivity in the brain of human and non-human primates: an immunohistochemical analysis in normal conditions and in Parkinsonian syndromes.

Zarate-Lagunes M, Gu WJ, Blanchard V, Francois C, Muriel MP, Mouatt-Prigent A, Bonici B, Parent A, Hartmann A, Yelnik J, Boehme GA, Pradier L, Moussaoui S, Faucheux B, Raisman-Vozari R, Agid Y, Brice A, Hirsch EC.

J Comp Neurol. 2001 Apr 2;432(2):184-96.

PMID:
11241385
19.

14-3-3eta is a novel regulator of parkin ubiquitin ligase.

Sato S, Chiba T, Sakata E, Kato K, Mizuno Y, Hattori N, Tanaka K.

EMBO J. 2006 Jan 11;25(1):211-21. Epub 2005 Aug 11.

20.

Parkin and defective ubiquitination in Parkinson's disease.

Dawson TM.

J Neural Transm Suppl. 2006;(70):209-13. Review.

PMID:
17017531

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