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Items: 1 to 20 of 114

1.

Regulation of embryonic endochondral ossification by Smurf2.

Wu Q, Wang M, Zuscik MJ, Chen D, O'Keefe RJ, Rosier RN.

J Orthop Res. 2008 May;26(5):704-12. doi: 10.1002/jor.20563.

2.

Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin.

Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN.

J Bone Miner Res. 2008 Apr;23(4):552-63.

3.

5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.

Zuscik MJ, Baden JF, Wu Q, Sheu TJ, Schwarz EM, Drissi H, O'Keefe RJ, Puzas JE, Rosier RN.

J Cell Biochem. 2004 May 15;92(2):316-31.

PMID:
15108358
4.

Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.

Li TF, Darowish M, Zuscik MJ, Chen D, Schwarz EM, Rosier RN, Drissi H, O'Keefe RJ.

J Bone Miner Res. 2006 Jan;21(1):4-16. Epub 2005 Sep 19.

5.

Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage.

Wu Q, Huang JH, Sampson ER, Kim KO, Zuscik MJ, O'Keefe RJ, Chen D, Rosier RN.

Exp Cell Res. 2009 Aug 15;315(14):2386-98. doi: 10.1016/j.yexcr.2009.05.019. Epub 2009 May 27.

6.

Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification.

Tamamura Y, Otani T, Kanatani N, Koyama E, Kitagaki J, Komori T, Yamada Y, Costantini F, Wakisaka S, Pacifici M, Iwamoto M, Enomoto-Iwamoto M.

J Biol Chem. 2005 May 13;280(19):19185-95. Epub 2005 Mar 10.

7.

Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.

Wu Q, Kim KO, Sampson ER, Chen D, Awad H, O'Brien T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ, Zuscik MJ, Rosier RN.

Arthritis Rheum. 2008 Oct;58(10):3132-44. doi: 10.1002/art.23946.

8.

Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling.

Hayata T, Ezura Y, Asashima M, Nishinakamura R, Noda M.

J Bone Miner Res. 2015 Feb;30(2):318-29. doi: 10.1002/jbmr.2343. Erratum in: J Bone Miner Res. 2015 May;30(5):947. Yoichi, Ezura [corrected to Ezura, Yoichi].

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12.

ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.

Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ.

J Bone Miner Res. 2003 Sep;18(9):1593-604.

13.

A role for the BMP antagonist chordin in endochondral ossification.

Zhang D, Ferguson CM, O'Keefe RJ, Puzas JE, Rosier RN, Reynolds PR.

J Bone Miner Res. 2002 Feb;17(2):293-300.

14.

Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.

Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.

J Biol Chem. 2008 Sep 5;283(36):24682-9. doi: 10.1074/jbc.M709857200. Epub 2008 Jul 10.

15.

RGD-CAP ((beta)ig-h3) is expressed in precartilage condensation and in prehypertrophic chondrocytes during cartilage development.

Ohno S, Doi T, Tsutsumi S, Okada Y, Yoneno K, Kato Y, Tanne K.

Biochim Biophys Acta. 2002 Aug 15;1572(1):114-22.

PMID:
12204340
16.

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.

Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N.

J Cell Biol. 2004 May 10;165(3):433-45. Epub 2004 May 3.

17.

Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development.

Ding M, Lu Y, Abbassi S, Li F, Li X, Song Y, Geoffroy V, Im HJ, Zheng Q.

J Cell Physiol. 2012 Oct;227(10):3446-56. doi: 10.1002/jcp.24045.

18.

TGF β-1 administration during ex vivo expansion of human articular chondrocytes in a serum-free medium redirects the cell phenotype toward hypertrophy.

Narcisi R, Quarto R, Ulivi V, Muraglia A, Molfetta L, Giannoni P.

J Cell Physiol. 2012 Sep;227(9):3282-90. doi: 10.1002/jcp.24024.

PMID:
22105490
19.

Transglutaminase 2 regulates early chondrogenesis and glycosaminoglycan synthesis.

Nurminsky D, Shanmugasundaram S, Deasey S, Michaud C, Allen S, Hendig D, Dastjerdi A, Francis-West P, Nurminskaya M.

Mech Dev. 2011 Mar-Apr;128(3-4):234-45. doi: 10.1016/j.mod.2010.11.007. Epub 2010 Dec 1.

20.

Beta-catenin, cartilage, and osteoarthritis.

Wu Q, Zhu M, Rosier RN, Zuscik MJ, O'Keefe RJ, Chen D.

Ann N Y Acad Sci. 2010 Mar;1192:344-50. doi: 10.1111/j.1749-6632.2009.05212.x. Review.

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