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Items: 1 to 20 of 177

1.

Emerging applications of network and pathway analysis in drug discovery and development.

Ganter B, Giroux CN.

Curr Opin Drug Discov Devel. 2008 Jan;11(1):86-94. Review.

PMID:
18175271
2.

Genomic approach to biomarker identification and its recent applications.

He YD.

Cancer Biomark. 2006;2(3-4):103-33. Review.

PMID:
17192065
3.

Emerging applications of kinetic biomarkers in preclinical and clinical drug development.

Turner SM, Hellerstein MK.

Curr Opin Drug Discov Devel. 2005 Jan;8(1):115-26. Review.

PMID:
15679179
4.

Biomedical applications of protein chips.

Ng JH, Ilag LL.

J Cell Mol Med. 2002 Jul-Sep;6(3):329-40. Review.

5.

Systems modeling: a pathway to drug discovery.

Rajasethupathy P, Vayttaden SJ, Bhalla US.

Curr Opin Chem Biol. 2005 Aug;9(4):400-6. Review.

PMID:
16006180
6.

Using bioinformatics techniques for gene identification in drug discovery and development.

Chen YP, Chen F.

Curr Drug Metab. 2008 Jul;9(6):567-73. Review.

PMID:
18680477
7.

Understanding mechanisms of toxicity: insights from drug discovery research.

Houck KA, Kavlock RJ.

Toxicol Appl Pharmacol. 2008 Mar 1;227(2):163-78. Epub 2007 Nov 4. Review.

PMID:
18063003
8.

Toxicogenomics in drug discovery and drug development: potential applications and future challenges.

Khor TO, Ibrahim S, Kong AN.

Pharm Res. 2006 Aug;23(8):1659-64. Review.

PMID:
16858654
9.

Biological complexity and drug discovery: a practical systems biology approach.

Berg EL, Kunkel EJ, Hytopoulos E.

Syst Biol (Stevenage). 2005 Dec;152(4):201-6.

PMID:
16986261
10.

ADME-Tox in drug discovery: integration of experimental and computational technologies.

Yu H, Adedoyin A.

Drug Discov Today. 2003 Sep 15;8(18):852-61. Review.

PMID:
12963322
11.

Natural products in drug discovery.

Harvey AL.

Drug Discov Today. 2008 Oct;13(19-20):894-901. doi: 10.1016/j.drudis.2008.07.004. Epub 2008 Aug 22. Review.

PMID:
18691670
12.

Assessing the impact of predictive biosimulation on drug discovery and development.

Michelson S.

J Bioinform Comput Biol. 2003 Apr;1(1):169-77.

PMID:
15290786
13.

Novel detection strategies for drug discovery.

Hemmilä IA, Hurskainen P.

Drug Discov Today. 2002 Sep 15;7(18 Suppl):S150-6. Review.

PMID:
12546882
14.

Knowledge representation model for systems-level analysis of signal transduction networks.

Lee DY, Zimmer R, Lee SY, Hanisch D, Park S.

Genome Inform. 2004;15(2):234-43.

PMID:
15706509
15.

Positioning ADMET in silico tools in drug discovery.

Modi S.

Drug Discov Today. 2004 Jan 1;9(1):14-5. No abstract available.

PMID:
14765543
16.

From drug target to leads--sketching a physicochemical pathway for lead molecule design in silico.

Shaikh SA, Jain T, Sandhu G, Latha N, Jayaram B.

Curr Pharm Des. 2007;13(34):3454-70. Review.

PMID:
18220783
17.

Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development.

Krishna R, Schaefer HG, Bjerrum OJ.

Eur J Pharm Sci. 2007 May;31(1):62-7. Epub 2007 Feb 20.

PMID:
17408933
18.

Systematic analysis of large screening sets in drug discovery.

Blower PE Jr, Cross KP, Fligner MA, Myatt GJ, Verducci JS, Yang C.

Curr Drug Discov Technol. 2004 Jan;1(1):37-47.

PMID:
16472218
19.

Network models in drug discovery and regenerative medicine.

Winkler DA.

Biotechnol Annu Rev. 2008;14:143-70. doi: 10.1016/S1387-2656(08)00005-7. Review.

PMID:
18606362
20.

Functional pathway pharmacology: chemical tools, pathway knowledge and mechanistic model-based interpretation of experimental data.

Hendriks BS.

Curr Opin Chem Biol. 2010 Aug;14(4):489-97. doi: 10.1016/j.cbpa.2010.06.167. Epub 2010 Jul 6. Review.

PMID:
20609614

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