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Items: 1 to 20 of 109


Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease.

Li S, Nikulina K, DeVoss J, Wu AJ, Strauss EC, Anderson MS, McNamara NA.

Invest Ophthalmol Vis Sci. 2008 Jan;49(1):34-41. doi: 10.1167/iovs.07-0685.


Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye.

Chen YT, Li S, Nikulina K, Porco T, Gallup M, McNamara N.

Mol Vis. 2009;15:563-76. Epub 2009 Mar 23.


Molecular mechanism of proinflammatory cytokine-mediated squamous metaplasia in human corneal epithelial cells.

Li S, Gallup M, Chen YT, McNamara NA.

Invest Ophthalmol Vis Sci. 2010 May;51(5):2466-75. doi: 10.1167/iovs.09-4677. Epub 2009 Dec 30.


Establishing PAX6 as a biomarker to detect early loss of ocular phenotype in human patients with Sjögren's syndrome.

McNamara NA, Gallup M, Porco TC.

Invest Ophthalmol Vis Sci. 2014 Sep 16;55(11):7079-84. doi: 10.1167/iovs.14-14828.


Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjögren's syndrome.

Chen YT, Nikulina K, Lazarev S, Bahrami AF, Noble LB, Gallup M, McNamara NA.

Am J Pathol. 2010 Sep;177(3):1333-43. doi: 10.2353/ajpath.2010.100227. Epub 2010 Aug 9.


Interleukin-1 receptor mediates the interplay between CD4+ T cells and ocular resident cells to promote keratinizing squamous metaplasia in Sjögren's syndrome.

Chen YT, Lazarev S, Bahrami AF, Noble LB, Chen FY, Zhou D, Gallup M, Yadav M, McNamara NA.

Lab Invest. 2012 Apr;92(4):556-70. doi: 10.1038/labinvest.2011.189. Epub 2012 Jan 9.


Topical administration of interleukin-1 receptor antagonist as a therapy for aqueous-deficient dry eye in autoimmune disease.

Vijmasi T, Chen FY, Chen YT, Gallup M, McNamara N.

Mol Vis. 2013 Sep 19;19:1957-65. eCollection 2013.


Critical involvement of macrophage infiltration in the development of Sjögren's syndrome-associated dry eye.

Zhou D, Chen YT, Chen F, Gallup M, Vijmasi T, Bahrami AF, Noble LB, van Rooijen N, McNamara NA.

Am J Pathol. 2012 Sep;181(3):753-60. doi: 10.1016/j.ajpath.2012.05.014. Epub 2012 Jul 4.


Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma.

De Paiva CS, Villarreal AL, Corrales RM, Rahman HT, Chang VY, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2553-60.


Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.

Chen FY, Lee A, Ge S, Nathan S, Knox SM, McNamara NA.

PLoS One. 2017 Sep 19;12(9):e0184916. doi: 10.1371/journal.pone.0184916. eCollection 2017.


Up-regulated gene expression in the conjunctival epithelium of patients with Sjögren's syndrome.

Kawasaki S, Kawamoto S, Yokoi N, Connon C, Minesaki Y, Kinoshita S, Okubo K.

Exp Eye Res. 2003 Jul;77(1):17-26.


Sjögren's syndrome associated dry eye in a mouse model is ameliorated by topical application of integrin α4 antagonist GW559090.

Contreras-Ruiz L, Mir FA, Turpie B, Krauss AH, Masli S.

Exp Eye Res. 2016 Feb;143:1-8. doi: 10.1016/j.exer.2015.10.008. Epub 2015 Oct 14.


Pax6 downregulation mediates abnormal lineage commitment of the ocular surface epithelium in aqueous-deficient dry eye disease.

Chen YT, Chen FY, Vijmasi T, Stephens DN, Gallup M, McNamara NA.

PLoS One. 2013 Oct 15;8(10):e77286. doi: 10.1371/journal.pone.0077286. eCollection 2013.


Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline.

De Paiva CS, Corrales RM, Villarreal AL, Farley W, Li DQ, Stern ME, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2006 Jul;47(7):2847-56.


Desiccating stress induces CD4+ T-cell-mediated Sjögren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-γ.

Zhang X, Chen W, De Paiva CS, Volpe EA, Gandhi NB, Farley WJ, Li DQ, Niederkorn JY, Stern ME, Pflugfelder SC.

Am J Pathol. 2011 Oct;179(4):1807-14. doi: 10.1016/j.ajpath.2011.06.030. Epub 2011 Aug 16.


Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.

Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.

Biochem Biophys Res Commun. 2013 Sep 13;439(1):96-102. doi: 10.1016/j.bbrc.2013.08.021. Epub 2013 Aug 13.


Expression of interferon-inducible T cell alpha chemoattractant (CXCL11) in the salivary glands of patients with Sjögren's syndrome.

Ogawa N, Kawanami T, Shimoyama K, Ping L, Sugai S.

Clin Immunol. 2004 Sep;112(3):235-8.


Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome.

Fava RA, Kennedy SM, Wood SG, Bolstad AI, Bienkowska J, Papandile A, Kelly JA, Mavragani CP, Gatumu M, Skarstein K, Browning JL.

Arthritis Res Ther. 2011;13(6):R182. doi: 10.1186/ar3507. Epub 2011 Nov 1.


An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse.

DeVoss JJ, LeClair NP, Hou Y, Grewal NK, Johannes KP, Lu W, Yang T, Meagher C, Fong L, Strauss EC, Anderson MS.

J Immunol. 2010 Apr 15;184(8):4236-46. doi: 10.4049/jimmunol.0902434. Epub 2010 Mar 17.


Quantification of conjunctival TNF-α in aqueous-deficient dry eye.

Caffery BE, Joyce E, Heynen ML, Ritter R 3rd, Jones LA, Senchyna M.

Optom Vis Sci. 2014 Feb;91(2):156-62. doi: 10.1097/OPX.0000000000000133.


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