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Items: 1 to 20 of 235

1.

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression.

Bray MS, Shaw CA, Moore MW, Garcia RA, Zanquetta MM, Durgan DJ, Jeong WJ, Tsai JY, Bugger H, Zhang D, Rohrwasser A, Rennison JH, Dyck JR, Litwin SE, Hardin PE, Chow CW, Chandler MP, Abel ED, Young ME.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1036-47. Epub 2007 Dec 21.

2.

Diurnal variations in myocardial metabolism.

Bray MS, Young ME.

Cardiovasc Res. 2008 Jul 15;79(2):228-37. doi: 10.1093/cvr/cvn054. Epub 2008 Feb 26. Review.

PMID:
18304930
3.

Circadian rhythms in myocardial metabolism and contractile function: influence of workload and oleate.

Durgan DJ, Moore MW, Ha NP, Egbejimi O, Fields A, Mbawuike U, Egbejimi A, Shaw CA, Bray MS, Nannegari V, Hickson-Bick DL, Heird WC, Dyck JR, Chandler MP, Young ME.

Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2385-93. Epub 2007 Jul 6.

4.

The circadian clock within the cardiomyocyte is essential for responsiveness of the heart to fatty acids.

Durgan DJ, Trexler NA, Egbejimi O, McElfresh TA, Suk HY, Petterson LE, Shaw CA, Hardin PE, Bray MS, Chandler MP, Chow CW, Young ME.

J Biol Chem. 2006 Aug 25;281(34):24254-69. Epub 2006 Jun 22.

5.
6.

Intrinsic diurnal variations in cardiac metabolism and contractile function.

Young ME, Razeghi P, Cedars AM, Guthrie PH, Taegtmeyer H.

Circ Res. 2001 Dec 7;89(12):1199-208.

7.

Circadian rhythms in cardiac gene expression.

Young ME.

Curr Hypertens Rep. 2003 Dec;5(6):445-53. Review.

PMID:
14594562
8.

Anticipating anticipation: pursuing identification of cardiomyocyte circadian clock function.

Young ME.

J Appl Physiol (1985). 2009 Oct;107(4):1339-47. doi: 10.1152/japplphysiol.00473.2009. Epub 2009 Jul 16. Review.

9.

Evidence suggesting that the cardiomyocyte circadian clock modulates responsiveness of the heart to hypertrophic stimuli in mice.

Durgan DJ, Tsai JY, Grenett MH, Pat BM, Ratcliffe WF, Villegas-Montoya C, Garvey ME, Nagendran J, Dyck JR, Bray MS, Gamble KL, Gimble JM, Young ME.

Chronobiol Int. 2011 Apr;28(3):187-203. doi: 10.3109/07420528.2010.550406.

10.

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

Mazumder PK, O'Neill BT, Roberts MW, Buchanan J, Yun UJ, Cooksey RC, Boudina S, Abel ED.

Diabetes. 2004 Sep;53(9):2366-74.

11.

Genetic components of the circadian clock regulate thrombogenesis in vivo.

Westgate EJ, Cheng Y, Reilly DF, Price TS, Walisser JA, Bradfield CA, FitzGerald GA.

Circulation. 2008 Apr 22;117(16):2087-95. doi: 10.1161/CIRCULATIONAHA.107.739227. Epub 2008 Apr 14.

12.

Functional and metabolic remodelling in GLUT4-deficient hearts confers hyper-responsiveness to substrate intervention.

Huggins CE, Domenighetti AA, Ritchie ME, Khalil N, Favaloro JM, Proietto J, Smyth GK, Pepe S, Delbridge LM.

J Mol Cell Cardiol. 2008 Feb;44(2):270-80. doi: 10.1016/j.yjmcc.2007.11.020. Epub 2007 Dec 8.

PMID:
18191142
13.

Diurnal profiling of neuroendocrine genes in murine heart, and shift in proopiomelanocortin gene expression with pressure-overload cardiac hypertrophy.

Chalmers JA, Lin SY, Martino TA, Arab S, Liu P, Husain M, Sole MJ, Belsham DD.

J Mol Endocrinol. 2008 Sep;41(3):117-24. doi: 10.1677/JME-08-0050. Epub 2008 Jun 12.

PMID:
18550896
14.

The cardiomyocyte molecular clock regulates the circadian expression of Kcnh2 and contributes to ventricular repolarization.

Schroder EA, Burgess DE, Zhang X, Lefta M, Smith JL, Patwardhan A, Bartos DC, Elayi CS, Esser KA, Delisle BP.

Heart Rhythm. 2015 Jun;12(6):1306-14. doi: 10.1016/j.hrthm.2015.02.019. Epub 2015 Feb 19.

15.

Cardiac-directed parvalbumin transgene expression in mice shows marked heart rate dependence of delayed Ca2+ buffering action.

Day SM, Coutu P, Wang W, Herron T, Turner I, Shillingford M, Lacross NC, Converso KL, Piao L, Li J, Lopatin AN, Metzger JM.

Physiol Genomics. 2008 May 13;33(3):312-22. doi: 10.1152/physiolgenomics.00302.2007. Epub 2008 Mar 11.

16.

Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock.

Tsai JY, Kienesberger PC, Pulinilkunnil T, Sailors MH, Durgan DJ, Villegas-Montoya C, Jahoor A, Gonzalez R, Garvey ME, Boland B, Blasier Z, McElfresh TA, Nannegari V, Chow CW, Heird WC, Chandler MP, Dyck JR, Bray MS, Young ME.

J Biol Chem. 2010 Jan 29;285(5):2918-29. doi: 10.1074/jbc.M109.077800. Epub 2009 Nov 25.

17.

Vascular circadian rhythms in a mouse vascular smooth muscle cell line (Movas-1).

Chalmers JA, Martino TA, Tata N, Ralph MR, Sole MJ, Belsham DD.

Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1529-38. doi: 10.1152/ajpregu.90572.2008. Epub 2008 Sep 3.

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19.

Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms.

Ko ML, Shi L, Tsai JY, Young ME, Neuendorff N, Earnest DJ, Ko GY.

J Biol Rhythms. 2011 Oct;26(5):412-22. doi: 10.1177/0748730411414170.

20.

Circadian rhythm of gene expression of myocardial contractile protein, left ventricular pressure and contractility.

Wang ZR, Wang L, Wan CM, Cornelissen G, Anand I, Halberg F.

Space Med Med Eng (Beijing). 1999 Dec;12(6):391-6.

PMID:
12432879

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