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Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation.

Zhou L, Huang H, Yuan CL, Keung W, Lopaschuk GD, Stanley WC.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H954-60.


Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power.

King KL, Okere IC, Sharma N, Dyck JR, Reszko AE, McElfresh TA, Kerner J, Chandler MP, Lopaschuk GD, Stanley WC.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1033-7.


Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat.

Sharma V, Dhillon P, Wambolt R, Parsons H, Brownsey R, Allard MF, McNeill JH.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1609-20. doi: 10.1152/ajpheart.00949.2007.


Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply.

Onay-Besikci A, Sambandam N.

Can J Physiol Pharmacol. 2006 Nov;84(11):1215-22.


Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels.

Hall JL, Lopaschuk GD, Barr A, Bringas J, Pizzurro RD, Stanley WC.

Cardiovasc Res. 1996 Nov;32(5):879-85.


Malonyl CoA control of fatty acid oxidation in the ischemic heart.

Dyck JR, Lopaschuk GD.

J Mol Cell Cardiol. 2002 Sep;34(9):1099-109. Review.


Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.

Dyck JR, Cheng JF, Stanley WC, Barr R, Chandler MP, Brown S, Wallace D, Arrhenius T, Harmon C, Yang G, Nadzan AM, Lopaschuk GD.

Circ Res. 2004 May 14;94(9):e78-84.


AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart.

Hopkins TA, Dyck JR, Lopaschuk GD.

Biochem Soc Trans. 2003 Feb;31(Pt 1):207-12. Review.


Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart.

Lopaschuk GD, Witters LA, Itoi T, Barr R, Barr A.

J Biol Chem. 1994 Oct 14;269(41):25871-8.


LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle.

Thomson DM, Brown JD, Fillmore N, Condon BM, Kim HJ, Barrow JR, Winder WW.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1572-9.


Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.

Saddik M, Gamble J, Witters LA, Lopaschuk GD.

J Biol Chem. 1993 Dec 5;268(34):25836-45.


gAd-globular head domain of adiponectin increases fatty acid oxidation in newborn rabbit hearts.

Onay-Besikci A, Altarejos JY, Lopaschuk GD.

J Biol Chem. 2004 Oct 22;279(43):44320-6.


Role of malonyl-CoA in heart disease and the hypothalamic control of obesity.

Folmes CD, Lopaschuk GD.

Cardiovasc Res. 2007 Jan 15;73(2):278-87. Review.


beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content.

Stanley WC, Meadows SR, Kivilo KM, Roth BA, Lopaschuk GD.

Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1626-31.

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