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Items: 1 to 20 of 228

1.

Treatment with insulin inhibits poly(ADP-ribose)polymerase activation in a rat model of endotoxemia.

Horváth EM, Benko R, Gero D, Kiss L, Szabó C.

Life Sci. 2008 Jan 16;82(3-4):205-9. Epub 2007 Nov 21.

2.

Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.

Mabley JG, Horváth EM, Murthy KG, Zsengellér Z, Vaslin A, Benko R, Kollai M, Szabó C.

J Pharmacol Exp Ther. 2005 Nov;315(2):812-20. Epub 2005 Aug 3.

3.

Rapid 'glycaemic swings' induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus.

Horváth EM, Benko R, Kiss L, Murányi M, Pék T, Fekete K, Bárány T, Somlai A, Csordás A, Szabo C.

Diabetologia. 2009 May;52(5):952-61. doi: 10.1007/s00125-009-1304-0. Epub 2009 Mar 5.

PMID:
19263033
4.

Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice.

Sriram CS, Jangra A, Gurjar SS, Hussain MI, Borah P, Lahkar M, Mohan P, Bezbaruah BK.

Pharmacol Biochem Behav. 2015 Jun;133:83-91. doi: 10.1016/j.pbb.2015.03.022. Epub 2015 Apr 9.

PMID:
25863272
5.

PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation.

Yang Z, Li L, Chen L, Yuan W, Dong L, Zhang Y, Wu H, Wang C.

J Immunol. 2014 Dec 15;193(12):6114-23. doi: 10.4049/jimmunol.1400359. Epub 2014 Nov 12.

6.

Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells.

Nakajima H, Nagaso H, Kakui N, Ishikawa M, Hiranuma T, Hoshiko S.

J Biol Chem. 2004 Oct 8;279(41):42774-86. Epub 2004 Aug 9.

7.

Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy.

Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, Obrosova IG.

Endocrinology. 2009 Dec;150(12):5273-83. doi: 10.1210/en.2009-0628. Epub 2009 Oct 23.

8.

Neuropilin-1 modulates vascular endothelial growth factor-induced poly(ADP-ribose)-polymerase leading to reduced cerebrovascular apoptosis.

Mey L, Hörmann M, Schleicher N, Reuter P, Dönges S, Kinscherf R, Gassmann M, Gerriets T, Al-Fakhri N.

Neurobiol Dis. 2013 Nov;59:111-25. doi: 10.1016/j.nbd.2013.06.009. Epub 2013 Jun 28.

PMID:
23816753
9.

TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes.

Roberge S, Roussel J, Andersson DC, Meli AC, Vidal B, Blandel F, Lanner JT, Le Guennec JY, Katz A, Westerblad H, Lacampagne A, Fauconnier J.

Cardiovasc Res. 2014 Jul 1;103(1):90-9. doi: 10.1093/cvr/cvu112. Epub 2014 May 6.

PMID:
24802330
10.

Activation and overexpression of PARP-1 in circulating mononuclear cells promote TNF-alpha and IL-6 expression in patients with unstable angina.

Huang D, Yang CZ, Yao L, Wang Y, Liao YH, Huang K.

Arch Med Res. 2008 Nov;39(8):775-84. doi: 10.1016/j.arcmed.2008.09.003.

PMID:
18996291
11.

Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation.

Pacher P, Mabley JG, Soriano FG, Liaudet L, Komjáti K, Szabó C.

Br J Pharmacol. 2002 Mar;135(6):1347-50.

12.

Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.

Szabó C, Pacher P, Zsengellér Z, Vaslin A, Komjáti K, Benkö R, Chen M, Mabley JG, Kollai M.

Mol Med. 2004 Jan-Jun;10(1-6):28-35.

13.

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells.

Du X, Matsumura T, Edelstein D, Rossetti L, Zsengellér Z, Szabó C, Brownlee M.

J Clin Invest. 2003 Oct;112(7):1049-57.

15.

Differential effects of PARP inhibition on vascular cell survival and ACAT-1 expression favouring atherosclerotic plaque stability.

Hans CP, Zerfaoui M, Naura AS, Catling A, Boulares AH.

Cardiovasc Res. 2008 Jun 1;78(3):429-39. doi: 10.1093/cvr/cvn018. Epub 2008 Jan 31.

PMID:
18245064
16.

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.

Szabó C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL.

J Clin Invest. 1997 Aug 1;100(3):723-35.

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19.

Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro.

Radovits T, Lin LN, Zotkina J, Gero D, Szabó C, Karck M, Szabó G.

Eur J Pharmacol. 2007 Jun 14;564(1-3):158-66. Epub 2007 Mar 12.

PMID:
17397824
20.

Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.

Geraets L, Moonen HJ, Brauers K, Gottschalk RW, Wouters EF, Bast A, Hageman GJ.

Eur J Pharmacol. 2007 Nov 14;573(1-3):241-8. Epub 2007 Jul 13.

PMID:
17643414

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