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Items: 1 to 20 of 85

1.

BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity.

Kang HJ, Kim HJ, Kwon SH, Kang BD, Eling TE, Lee SH, Bae I.

Cancer Chemother Pharmacol. 2008 Sep;62(4):689-97. Epub 2007 Dec 12.

PMID:
18074135
2.

BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells.

Kang HJ, Kim HJ, Kim SK, Barouki R, Cho CH, Khanna KK, Rosen EM, Bae I.

J Biol Chem. 2006 May 26;281(21):14654-62. Epub 2006 Mar 27.

4.

Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells.

Brantley E, Trapani V, Alley MC, Hose CD, Bradshaw TD, Stevens MF, Sausville EA, Stinson SF.

Drug Metab Dispos. 2004 Dec;32(12):1392-401. Epub 2004 Sep 8.

5.

CYP2S1 and CYP2W1 mediate 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW-610, NSC 721648) sensitivity in breast and colorectal cancer cells.

Tan BS, Tiong KH, Muruhadas A, Randhawa N, Choo HL, Bradshaw TD, Stevens MF, Leong CO.

Mol Cancer Ther. 2011 Oct;10(10):1982-92. doi: 10.1158/1535-7163.MCT-11-0391. Epub 2011 Aug 10.

6.

DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells.

Trapani V, Patel V, Leong CO, Ciolino HP, Yeh GC, Hose C, Trepel JB, Stevens MF, Sausville EA, Loaiza-Pérez AI.

Br J Cancer. 2003 Feb 24;88(4):599-605.

7.

Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells.

Khan S, Liu S, Stoner M, Safe S.

Toxicol Appl Pharmacol. 2007 Aug 15;223(1):28-38. Epub 2007 May 25.

8.

CYP1A1 is overexpressed upon incubation of breast cancer cells with a polyphenolic cocoa extract.

Oleaga C, García M, Solé A, Ciudad CJ, Izquierdo-Pulido M, Noé V.

Eur J Nutr. 2012 Jun;51(4):465-76. doi: 10.1007/s00394-011-0231-2. Epub 2011 Aug 6.

PMID:
21822728
9.

Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells.

Loaiza-Pérez AI, Kenney S, Boswell J, Hollingshead M, Alley MC, Hose C, Ciolino HP, Yeh GC, Trepel JB, Vistica DT, Sausville EA.

Mol Cancer Ther. 2004 Jun;3(6):715-25.

10.

Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.

McLean LS, Watkins CN, Campbell P, Zylstra D, Rowland L, Amis LH, Scott L, Babb CE, Livingston WJ, Darwanto A, Davis WL Jr, Senthil M, Sowers LC, Brantley E.

Chem Res Toxicol. 2015 May 18;28(5):855-71. doi: 10.1021/tx500485v. Epub 2015 Apr 1.

11.

Suppressive effects of caraway (Carum carvi) extracts on 2, 3, 7, 8-tetrachloro-dibenzo-p-dioxin-dependent gene expression of cytochrome P450 1A1 in the rat H4IIE cells.

Naderi-Kalali B, Allameh A, Rasaee MJ, Bach HJ, Behechti A, Doods K, Kettrup A, Schramm KW.

Toxicol In Vitro. 2005 Apr;19(3):373-7. Epub 2005 Jan 26.

PMID:
15713544
12.

Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole.

Loaiza-Pérez AI, Trapani V, Hose C, Singh SS, Trepel JB, Stevens MF, Bradshaw TD, Sausville EA.

Mol Pharmacol. 2002 Jan;61(1):13-9.

13.

The experimental antitumor agents Phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.

Fichtner I, Monks A, Hose C, Stevens MF, Bradshaw TD.

Breast Cancer Res Treat. 2004 Sep;87(1):97-107.

PMID:
15377855
14.

BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses using a breast cancer cell line and tumoral xenograft model.

Yu X, Luo Y, Zhou Y, Zhang Q, Wang J, Wei N, Mi M, Zhu J, Wang B, Chang H, Tang Y.

Int J Oncol. 2008 Sep;33(3):555-63.

PMID:
18695886
15.

Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals.

Korashy HM, El-Kadi AO.

Toxicol Sci. 2005 Nov;88(1):39-51. Epub 2005 Aug 10.

PMID:
16093525
16.

Aryl hydrocarbon receptor mediates laminar fluid shear stress-induced CYP1A1 activation and cell cycle arrest in vascular endothelial cells.

Han Z, Miwa Y, Obikane H, Mitsumata M, Takahashi-Yanaga F, Morimoto S, Sasaguri T.

Cardiovasc Res. 2008 Mar 1;77(4):809-18. Epub 2007 Dec 7.

PMID:
18065768
18.

2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the aryl hydrocarbon receptor.

Bazzi R, Bradshaw TD, Rowlands JC, Stevens MF, Bell DR.

Toxicol Appl Pharmacol. 2009 May 15;237(1):102-10. doi: 10.1016/j.taap.2009.02.015. Epub 2009 Mar 2.

PMID:
19265716
20.

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