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Items: 1 to 20 of 111

1.

Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte.

León H, Baczkó I, Sawicki G, Light PE, Schulz R.

Br J Pharmacol. 2008 Feb;153(4):676-83. Epub 2007 Dec 10.

2.

Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2.

Wang W, Sawicki G, Schulz R.

Cardiovasc Res. 2002 Jan;53(1):165-74.

PMID:
11744025
3.

Ischemia induced peroxynitrite dependent modifications of cardiomyocyte MLC1 increases its degradation by MMP-2 leading to contractile dysfunction.

Polewicz D, Cadete VJ, Doroszko A, Hunter BE, Sawicka J, Szczesna-Cordary D, Light PE, Sawicki G.

J Cell Mol Med. 2011 May;15(5):1136-47. doi: 10.1111/j.1582-4934.2010.01094.x. Epub 2010 May 26.

4.

Hydrogen peroxide causes cardiac dysfunction independent from its effects on matrix metalloproteinase-2 activation.

León H, Bautista-López N, Sawicka J, Schulz R.

Can J Physiol Pharmacol. 2007 Mar-Apr;85(3-4):341-8.

PMID:
17612643
5.

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects.

Katori T, Donzelli S, Tocchetti CG, Miranda KM, Cormaci G, Thomas DD, Ketner EA, Lee MJ, Mancardi D, Wink DA, Kass DA, Paolocci N.

Free Radic Biol Med. 2006 Nov 15;41(10):1606-18. Epub 2006 Sep 5.

PMID:
17045928
6.

Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction.

Gao CQ, Sawicki G, Suarez-Pinzon WL, Csont T, Wozniak M, Ferdinandy P, Schulz R.

Cardiovasc Res. 2003 Feb;57(2):426-33.

PMID:
12566115
7.

Inhibitory effects of caspase inhibitors on the activity of matrix metalloproteinase-2.

Castro MM, Fuah J, Ali M, Sung M, Schulz J, Kondo MY, Fan X, Holt A, Schulz R.

Biochem Pharmacol. 2013 Aug 15;86(4):469-75. doi: 10.1016/j.bcp.2013.06.003. Epub 2013 Jun 14.

PMID:
23774623
8.
9.

Role of iNOS and peroxynitrite-matrix metalloproteinase-2 signaling in myocardial late preconditioning in rats.

Bencsik P, Kupai K, Giricz Z, Görbe A, Pipis J, Murlasits Z, Kocsis GF, Varga-Orvos Z, Puskás LG, Csonka C, Csont T, Ferdinandy P.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H512-8. doi: 10.1152/ajpheart.00052.2010. Epub 2010 Jun 11.

10.

Arrhythmogenic peroxynitrite-induced alterations in mammalian heart contractility and its prevention with quercetin-filled liposomes.

Soloviev A, Stefanov A, Parshikov A, Khromov A, Moibenko A, Kvotchina L, Balavoine G, Geletii Y.

Cardiovasc Toxicol. 2002;2(2):129-39.

PMID:
12271156
11.

Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia.

Moshal KS, Tipparaju SM, Vacek TP, Kumar M, Singh M, Frank IE, Patibandla PK, Tyagi N, Rai J, Metreveli N, Rodriguez WE, Tseng MT, Tyagi SC.

Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H890-7. doi: 10.1152/ajpheart.00099.2008. Epub 2008 Jun 20.

12.
13.

Peroxynitrite-induced cardiac depression: role of myofilament desensitization and cGMP pathway.

Brunner F, Wölkart G.

Cardiovasc Res. 2003 Nov 1;60(2):355-64.

PMID:
14613865
14.

Matrix metalloproteinase-2 degrades the cytoskeletal protein alpha-actinin in peroxynitrite mediated myocardial injury.

Sung MM, Schulz CG, Wang W, Sawicki G, Bautista-López NL, Schulz R.

J Mol Cell Cardiol. 2007 Oct;43(4):429-36. Epub 2007 Jul 31.

PMID:
17854826
15.
16.
17.

Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia.

Cena JJ, Lalu MM, Cho WJ, Chow AK, Bagdan ML, Daniel EE, Castro MM, Schulz R.

Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H45-51. doi: 10.1152/ajpheart.00273.2009. Epub 2009 Oct 16.

18.

Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione.

Viappiani S, Nicolescu AC, Holt A, Sawicki G, Crawford BD, León H, van Mulligen T, Schulz R.

Biochem Pharmacol. 2009 Mar 1;77(5):826-34. doi: 10.1016/j.bcp.2008.11.004. Epub 2008 Nov 12.

PMID:
19046943
19.

Chronic ventricular myocyte-specific overexpression of angiotensin II type 2 receptor results in intrinsic myocyte contractile dysfunction.

Nakayama M, Yan X, Price RL, Borg TK, Ito K, Sanbe A, Robbins J, Lorell BH.

Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H317-27. Epub 2004 Sep 16.

20.

Acetaminophen attenuates peroxynitrite-activated matrix metalloproteinase-2-mediated troponin I cleavage in the isolated guinea pig myocardium.

Rork TH, Hadzimichalis NM, Kappil MA, Merrill GF.

J Mol Cell Cardiol. 2006 Apr;40(4):553-61. Epub 2006 Mar 10.

PMID:
16530785

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