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Items: 1 to 20 of 59

1.

Focus on molecules: optineurin.

Chalasani ML, Balasubramanian D, Swarup G.

Exp Eye Res. 2008 Jul;87(1):1-2. Epub 2007 Nov 5. No abstract available.

PMID:
18068704
2.

A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

Chalasani ML, Radha V, Gupta V, Agarwal N, Balasubramanian D, Swarup G.

Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1607-14.

PMID:
17389490
3.

Molecular cloning, genomic structure, and protein characterization of mouse optineurin.

Rezaie T, Sarfarazi M.

Genomics. 2005 Jan;85(1):131-8.

PMID:
15607428
4.

Optineurin and its mutants: molecules associated with some forms of glaucoma.

Chalasani ML, Swarup G, Balasubramanian D.

Ophthalmic Res. 2009;42(4):176-84. doi: 10.1159/000232400. Epub 2009 Aug 7. Review.

PMID:
19672125
5.

Interaction between two glaucoma genes, optineurin and myocilin.

Park BC, Tibudan M, Samaraweera M, Shen X, Yue BY.

Genes Cells. 2007 Aug;12(8):969-79.

6.

Functional analysis of optineurin and some of its disease-associated mutants.

Bansal M, Swarup G, Balasubramanian D.

IUBMB Life. 2015 Feb;67(2):120-8. doi: 10.1002/iub.1355. Epub 2015 Apr 9. Review.

7.

A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.

Sirohi K, Kumari A, Radha V, Swarup G.

PLoS One. 2015 Sep 16;10(9):e0138289. doi: 10.1371/journal.pone.0138289. eCollection 2015.

8.

Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene.

Ying H, Shen X, Park B, Yue BY.

PLoS One. 2010 Feb 11;5(2):e9168. doi: 10.1371/journal.pone.0009168.

9.

Complex genetics of glaucoma susceptibility.

Libby RT, Gould DB, Anderson MG, John SW.

Annu Rev Genomics Hum Genet. 2005;6:15-44. Review.

PMID:
16124852
10.

[Glaucoma genetics: the light at the end of the tunnel fourteen years later].

Escribano J.

Arch Soc Esp Oftalmol. 2010 Nov;85(11):353-4. doi: 10.1016/j.oftal.2010.12.002. Spanish. No abstract available.

PMID:
21277460
11.

Effects of abnormal optineurin expression on the survival of the rat retinal ganglion cell line RGC-5.

Xu ZR, Jiang FG, Chen F.

Genet Mol Res. 2015 Aug 7;14(3):9171-80. doi: 10.4238/2015.August.7.27.

12.

Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics.

Paulus JD, Link BA.

PLoS One. 2014 Oct 16;9(10):e109922. doi: 10.1371/journal.pone.0109922. eCollection 2014.

13.

Optineurin, a multifunctional protein involved in glaucoma, amyotrophic lateral sclerosis and antiviral signalling.

Swarup G, Nagabhushana A.

J Biosci. 2010 Dec;35(4):501-5. No abstract available.

15.

The genetics of primary open-angle glaucoma: a review.

Allingham RR, Liu Y, Rhee DJ.

Exp Eye Res. 2009 Apr;88(4):837-44. doi: 10.1016/j.exer.2008.11.003. Epub 2008 Nov 14. Review.

PMID:
19061886
16.

[Retinal ganglion cells death in glaucoma--mechanism and potential treatment. Part II].

Rokicki W, Dorecka M, Romaniuk W.

Klin Oczna. 2007;109(7-9):353-5. Review. Polish.

PMID:
18260297
17.

Distribution and localization of abnormally expressed OPTN proteins in RGC5 retinal ganglion cells and their effects on subcellular morphology.

Xu ZR, Jiang FG, Chen F.

Genet Mol Res. 2015 Oct 5;14(4):12093-101. doi: 10.4238/2015.October.5.22.

18.

Agmatine inhibits hypoxia-induced TNF-alpha release from cultured retinal ganglion cells.

Hong S, Park K, Kim CY, Seong GJ.

Biocell. 2008 Aug;32(2):201-5.

PMID:
18825914
19.

Lack of association between optineurin gene variants T34T, E50K, M98K, 691_692insAG and R545Q and primary open angle glaucoma in Brazilian patients.

Caixeta-Umbelino C, de Vasconcellos JP, Costa VP, Kasahara N, Della Paolera M, de Almeida GV, Cohen R, Mandia C Jr, Rocha MN, Richeti F, Longui CA, de Melo MB.

Ophthalmic Genet. 2009 Mar;30(1):13-8. doi: 10.1080/13816810802502970.

PMID:
19172505
20.

Soluble amyloid beta oligomers may contribute to apoptosis of retinal ganglion cells in glaucoma.

Yin H, Chen L, Chen X, Liu X.

Med Hypotheses. 2008;71(1):77-80. doi: 10.1016/j.mehy.2008.01.030. Epub 2008 Apr 11.

PMID:
18406539

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