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Raptor-rictor axis in TGFbeta-induced protein synthesis.

Das F, Ghosh-Choudhury N, Mahimainathan L, Venkatesan B, Feliers D, Riley DJ, Kasinath BS, Choudhury GG.

Cell Signal. 2008 Feb;20(2):409-23. Epub 2007 Nov 7.


IGF-1 stimulates protein synthesis by enhanced signaling through mTORC1 in bovine mammary epithelial cells.

Burgos SA, Cant JP.

Domest Anim Endocrinol. 2010 May;38(4):211-21. doi: 10.1016/j.domaniend.2009.10.005. Epub 2009 Nov 28.


IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.

Bibollet-Bahena O, Almazan G.

J Neurochem. 2009 Jun;109(5):1440-51. doi: 10.1111/j.1471-4159.2009.06071.x. Epub 2009 Mar 28.


TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion.

Dey N, Ghosh-Choudhury N, Kasinath BS, Choudhury GG.

PLoS One. 2012;7(8):e42316. doi: 10.1371/journal.pone.0042316. Epub 2012 Aug 3.


Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation.

Grech G, Blázquez-Domingo M, Kolbus A, Bakker WJ, Müllner EW, Beug H, von Lindern M.

Blood. 2008 Oct 1;112(7):2750-60. doi: 10.1182/blood-2008-01-133140. Epub 2008 Jul 14.


TGFβ-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy.

Das F, Ghosh-Choudhury N, Bera A, Kasinath BS, Choudhury GG.

J Cell Physiol. 2013 Jul;228(7):1617-26. doi: 10.1002/jcp.24327.


Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.

Bianchini A, Loiarro M, Bielli P, Busà R, Paronetto MP, Loreni F, Geremia R, Sette C.

Carcinogenesis. 2008 Dec;29(12):2279-88. doi: 10.1093/carcin/bgn221. Epub 2008 Sep 22.


mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.

Hresko RC, Mueckler M.

J Biol Chem. 2005 Dec 9;280(49):40406-16. Epub 2005 Oct 11.


A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.

Aoki M, Blazek E, Vogt PK.

Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):136-41.


AKT-independent phosphorylation of TSC2 and activation of mTOR and ribosomal protein S6 kinase signaling by prostaglandin F2alpha.

Arvisais EW, Romanelli A, Hou X, Davis JS.

J Biol Chem. 2006 Sep 15;281(37):26904-13. Epub 2006 Jul 1.


Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.

Lekmine F, Uddin S, Sassano A, Parmar S, Brachmann SM, Majchrzak B, Sonenberg N, Hay N, Fish EN, Platanias LC.

J Biol Chem. 2003 Jul 25;278(30):27772-80. Epub 2003 May 20.


Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy.

Kemi OJ, Ceci M, Wisloff U, Grimaldi S, Gallo P, Smith GL, Condorelli G, Ellingsen O.

J Cell Physiol. 2008 Feb;214(2):316-21.


hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.

Byfield MP, Murray JT, Backer JM.

J Biol Chem. 2005 Sep 23;280(38):33076-82. Epub 2005 Jul 27.


Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells.

Davies CC, Mason J, Wakelam MJ, Young LS, Eliopoulos AG.

J Biol Chem. 2004 Jan 9;279(2):1010-9. Epub 2003 Oct 27.


Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.

Vary TC, Lynch CJ.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E631-42. Epub 2005 Nov 1.


Time course changes in signaling pathways and protein synthesis in C2C12 myotubes following AMPK activation by AICAR.

Williamson DL, Bolster DR, Kimball SR, Jefferson LS.

Am J Physiol Endocrinol Metab. 2006 Jul;291(1):E80-9.


PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.

Woo SY, Kim DH, Jun CB, Kim YM, Haar EV, Lee SI, Hegg JW, Bandhakavi S, Griffin TJ, Kim DH.

J Biol Chem. 2007 Aug 31;282(35):25604-12. Epub 2007 Jun 28.

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