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Items: 1 to 20 of 241

1.

The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase.

Abu-Farha M, Lambert JP, Al-Madhoun AS, Elisma F, Skerjanc IS, Figeys D.

Mol Cell Proteomics. 2008 Mar;7(3):560-72. Epub 2007 Dec 7.

2.

Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2.

Abu-Farha M, Lanouette S, Elisma F, Tremblay V, Butson J, Figeys D, Couture JF.

J Mol Cell Biol. 2011 Oct;3(5):301-8. doi: 10.1093/jmcb/mjr025.

PMID:
22028380
3.

Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins.

Xu S, Zhong C, Zhang T, Ding J.

J Mol Cell Biol. 2011 Oct;3(5):293-300. doi: 10.1093/jmcb/mjr015. Epub 2011 Jul 1.

PMID:
21724641
4.

Biochemical characterization of human SET and MYND domain-containing protein 2 methyltransferase.

Wu J, Cheung T, Grande C, Ferguson AD, Zhu X, Theriault K, Code E, Birr C, Keen N, Chen H.

Biochemistry. 2011 Jul 26;50(29):6488-97. doi: 10.1021/bi200725p. Epub 2011 Jun 29.

PMID:
21678921
5.

Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity.

Kim JY, Kee HJ, Choe NW, Kim SM, Eom GH, Baek HJ, Kook H, Kook H, Seo SB.

Mol Cell Biol. 2008 Mar;28(6):2023-34. doi: 10.1128/MCB.02130-07. Epub 2008 Jan 2.

6.

Repression of p53 activity by Smyd2-mediated methylation.

Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T, Berger SL.

Nature. 2006 Nov 30;444(7119):629-32. Epub 2006 Nov 15.

PMID:
17108971
8.

The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.

Liu C, Fang X, Ge Z, Jalink M, Kyo S, Björkholm M, Gruber A, Sjöberg J, Xu D.

Cancer Res. 2007 Mar 15;67(6):2626-31.

9.

Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.

Sun XJ, Wei J, Wu XY, Hu M, Wang L, Wang HH, Zhang QH, Chen SJ, Huang QH, Chen Z.

J Biol Chem. 2005 Oct 21;280(42):35261-71. Epub 2005 Aug 22.

10.

Regulation of p53 activity through lysine methylation.

Chuikov S, Kurash JK, Wilson JR, Xiao B, Justin N, Ivanov GS, McKinney K, Tempst P, Prives C, Gamblin SJ, Barlev NA, Reinberg D.

Nature. 2004 Nov 18;432(7015):353-60. Epub 2004 Nov 3.

11.

Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity.

Kim SM, Kee HJ, Eom GH, Choe NW, Kim JY, Kim YS, Kim SK, Kook H, Kook H, Seo SB.

Biochem Biophys Res Commun. 2006 Jun 23;345(1):318-23. Epub 2006 Apr 27.

PMID:
16682010
12.

Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation.

Zhang X, Tanaka K, Yan J, Li J, Peng D, Jiang Y, Yang Z, Barton MC, Wen H, Shi X.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17284-9. doi: 10.1073/pnas.1307959110. Epub 2013 Oct 7.

13.

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.

Shirato H, Ogawa S, Nakajima K, Inagawa M, Kojima M, Tachibana M, Shinkai Y, Takeuchi T.

J Biol Chem. 2009 Jan 9;284(2):733-9. doi: 10.1074/jbc.M804994200. Epub 2008 Nov 14.

14.

Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly.

Sampath SC, Marazzi I, Yap KL, Sampath SC, Krutchinsky AN, Mecklenbräuker I, Viale A, Rudensky E, Zhou MM, Chait BT, Tarakhovsky A.

Mol Cell. 2007 Aug 17;27(4):596-608.

16.

Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells.

Silva FP, Hamamoto R, Kunizaki M, Tsuge M, Nakamura Y, Furukawa Y.

Oncogene. 2008 Apr 24;27(19):2686-92. Epub 2007 Nov 12.

PMID:
17998933
17.

Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.

Voelkel T, Andresen C, Unger A, Just S, Rottbauer W, Linke WA.

Biochim Biophys Acta. 2013 Apr;1833(4):812-22. doi: 10.1016/j.bbamcr.2012.09.012. Epub 2012 Oct 6.

18.

RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.

Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J.

Genes Cells. 2007 Jun;12(6):811-26.

19.

Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma.

Komatsu S, Imoto I, Tsuda H, Kozaki KI, Muramatsu T, Shimada Y, Aiko S, Yoshizumi Y, Ichikawa D, Otsuji E, Inazawa J.

Carcinogenesis. 2009 Jul;30(7):1139-46. doi: 10.1093/carcin/bgp116. Epub 2009 May 7.

PMID:
19423649
20.

Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase.

Qian C, Wang X, Manzur K, Sachchidanand, Farooq A, Zeng L, Wang R, Zhou MM.

J Mol Biol. 2006 May 26;359(1):86-96. Epub 2006 Mar 20.

PMID:
16603186

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