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Items: 1 to 20 of 101

1.

Variation of macrophage tropism among HIV-1 R5 envelopes in brain and other tissues.

Peters PJ, Dueñas-Decamp MJ, Sullivan WM, Clapham PR.

J Neuroimmune Pharmacol. 2007 Mar;2(1):32-41. Epub 2006 Nov 7. Review.

PMID:
18040824
3.

HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.

Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR.

J Virol. 2018 Jan 2;92(2). pii: e00841-17. doi: 10.1128/JVI.00841-17. Print 2018 Jan 15.

PMID:
29118121
4.

Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis.

Peters PJ, Sullivan WM, Duenas-Decamp MJ, Bhattacharya J, Ankghuambom C, Brown R, Luzuriaga K, Bell J, Simmonds P, Ball J, Clapham PR.

J Virol. 2006 Jul;80(13):6324-32.

5.

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.

Peters PJ, Duenas-Decamp MJ, Sullivan WM, Brown R, Ankghuambom C, Luzuriaga K, Robinson J, Burton DR, Bell J, Simmonds P, Ball J, Clapham PR.

Retrovirology. 2008 Jan 18;5:5. doi: 10.1186/1742-4690-5-5.

6.

Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes.

Duenas-Decamp MJ, Peters PJ, Burton D, Clapham PR.

J Virol. 2009 Mar;83(6):2575-83. doi: 10.1128/JVI.02133-08. Epub 2009 Jan 7.

7.

HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages.

Musich T, O'Connell O, Gonzalez-Perez MP, Derdeyn CA, Peters PJ, Clapham PR.

Retrovirology. 2015 Mar 14;12:25. doi: 10.1186/s12977-015-0141-0.

8.

Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue.

Gonzalez-Perez MP, O'Connell O, Lin R, Sullivan WM, Bell J, Simmonds P, Clapham PR.

Retrovirology. 2012 Mar 15;9:20. doi: 10.1186/1742-4690-9-20.

9.

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity.

Gorry PR, Bristol G, Zack JA, Ritola K, Swanstrom R, Birch CJ, Bell JE, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky SM, Gabuzda D.

J Virol. 2001 Nov;75(21):10073-89.

10.

Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism.

O'Connell O, Repik A, Reeves JD, Gonzalez-Perez MP, Quitadamo B, Anton ED, Duenas-Decamp M, Peters P, Lin R, Zolla-Pazner S, Corti D, Wallace A, Wang S, Kong XP, Lu S, Clapham PR.

J Virol. 2013 Jan;87(1):187-98. doi: 10.1128/JVI.01834-12. Epub 2012 Oct 10.

11.

Phenotypic Correlates of HIV-1 Macrophage Tropism.

Arrildt KT, LaBranche CC, Joseph SB, Dukhovlinova EN, Graham WD, Ping LH, Schnell G, Sturdevant CB, Kincer LP, Mallewa M, Heyderman RS, Rie AV, Cohen MS, Spudich S, Price RW, Montefiori DC, Swanstrom R.

J Virol. 2015 Nov;89(22):11294-311. doi: 10.1128/JVI.00946-15. Epub 2015 Sep 2.

12.

The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors.

Rossi F, Querido B, Nimmagadda M, Cocklin S, Navas-Martín S, Martín-García J.

Retrovirology. 2008 Oct 6;5:89. doi: 10.1186/1742-4690-5-89.

13.

Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities.

Joseph SB, Arrildt KT, Swanstrom AE, Schnell G, Lee B, Hoxie JA, Swanstrom R.

J Virol. 2014 Feb;88(4):1858-69. doi: 10.1128/JVI.02477-13. Epub 2013 Dec 4.

14.

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

Dunfee RL, Thomas ER, Gorry PR, Wang J, Taylor J, Kunstman K, Wolinsky SM, Gabuzda D.

Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15160-5. Epub 2006 Oct 2.

15.

Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.

Peters PJ, Gonzalez-Perez MP, Musich T, Moore Simas TA, Lin R, Morse AN, Shattock RJ, Derdeyn CA, Clapham PR.

Retrovirology. 2015 Jun 9;12:48. doi: 10.1186/s12977-015-0176-2.

16.

HIV-1 replication in the central nervous system occurs in two distinct cell types.

Schnell G, Joseph S, Spudich S, Price RW, Swanstrom R.

PLoS Pathog. 2011 Oct;7(10):e1002286. doi: 10.1371/journal.ppat.1002286. Epub 2011 Oct 6.

17.

Viral determinants of HIV-1 macrophage tropism.

Duncan CJ, Sattentau QJ.

Viruses. 2011 Nov;3(11):2255-79. doi: 10.3390/v3112255. Epub 2011 Nov 15. Review.

18.

Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis.

Duenas-Decamp MJ, Peters PJ, Repik A, Musich T, Gonzalez-Perez MP, Caron C, Brown R, Ball J, Clapham PR.

Future Virol. 2010 Jul;5(4):435-451.

19.

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

Gorry PR, Taylor J, Holm GH, Mehle A, Morgan T, Cayabyab M, Farzan M, Wang H, Bell JE, Kunstman K, Moore JP, Wolinsky SM, Gabuzda D.

J Virol. 2002 Jun;76(12):6277-92.

20.

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