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Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis.

Soundararajan R, Wishart AD, Rupasinghe HP, Arcellana-Panlilio M, Nelson CM, Mayne M, Robertson GS.

J Biol Chem. 2008 Jan 25;283(4):2231-45. Epub 2007 Nov 20.


Human caspase 7 is positively controlled by SREBP-1 and SREBP-2.

Gibot L, Follet J, Metges JP, Auvray P, Simon B, Corcos L, Le Jossic-Corcos C.

Biochem J. 2009 May 27;420(3):473-83. doi: 10.1042/BJ20082057.


Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein-2 and enhances cholesterol efflux in hepatic cells.

Choi MC, Lee YU, Kim SH, Lee JH, Park JH, Streb JW, Oh DY, Im SA, Kim TY, Jong HS, Bang YJ.

Int J Biochem Cell Biol. 2008;40(11):2534-43. doi: 10.1016/j.biocel.2008.04.020. Epub 2008 May 20.


Caspase-2, a novel lipid sensor under the control of sterol regulatory element binding protein 2.

Logette E, Le Jossic-Corcos C, Masson D, Solier S, Sequeira-Legrand A, Dugail I, Lemaire-Ewing S, Desoche L, Solary E, Corcos L.

Mol Cell Biol. 2005 Nov;25(21):9621-31.


Cytoprotective effect of polypeptide from Chlamys farreri on neuroblastoma (SH-SY5Y) cells following HO exposure involves scavenging ROS and inhibition JNK phosphorylation.

Ye J, Han Y, Wang C, Yu W.

J Neurochem. 2009 Oct;111(2):441-51. doi: 10.1111/j.1471-4159.2009.06328.x. Epub 2009 Aug 3.


Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: the potential involvement of the RNA-binding protein HuR.

Amadio M, Scapagnini G, Laforenza U, Intrieri M, Romeo L, Govoni S, Pascale A.

Curr Pharm Des. 2008;14(26):2651-8.


Quercetin protects neuroblastoma SH-SY5Y cells against oxidative stress by inhibiting expression of Krüppel-like factor 4.

Xi J, Zhang B, Luo F, Liu J, Yang T.

Neurosci Lett. 2012 Oct 11;527(2):115-20. doi: 10.1016/j.neulet.2012.08.082. Epub 2012 Sep 7.


The radical scavenger CR-6 protects SH-SY5Y neuroblastoma cells from oxidative stress-induced apoptosis: effect on survival pathways.

Sanvicens N, Gómez-Vicente V, Messeguer A, Cotter TG.

J Neurochem. 2006 Aug;98(3):735-47. Epub 2006 Jun 19.


Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver.

Bennett MK, Seo YK, Datta S, Shin DJ, Osborne TF.

J Biol Chem. 2008 Jun 6;283(23):15628-37. doi: 10.1074/jbc.M800391200. Epub 2008 Apr 15.


Stimulatory heterotrimeric GTP-binding protein inhibits hydrogen peroxide-induced apoptosis by repressing BAK induction in SH-SY5Y human neuroblastoma cells.

Kim SY, Seo M, Kim Y, Lee YI, Oh JM, Cho EA, Kang JS, Juhnn YS.

J Biol Chem. 2008 Jan 18;283(3):1350-61. Epub 2007 Nov 8.


Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death.

Fordel E, Thijs L, Martinet W, Lenjou M, Laufs T, Van Bockstaele D, Moens L, Dewilde S.

Neurosci Lett. 2006 Dec 20;410(2):146-51.


Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors.

Woo CW, Siow YL, Pierce GN, Choy PC, Minuk GY, Mymin D, O K.

Am J Physiol Endocrinol Metab. 2005 May;288(5):E1002-10. Epub 2005 Jan 11.


Digoxin and ouabain increase the synthesis of cholesterol in human liver cells.

Campia I, Gazzano E, Pescarmona G, Ghigo D, Bosia A, Riganti C.

Cell Mol Life Sci. 2009 May;66(9):1580-94. doi: 10.1007/s00018-009-9018-5.


Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.

Najem D, Bamji-Mirza M, Yang Z, Zhang W.

Neurosci Bull. 2016 Jun;32(3):227-38. doi: 10.1007/s12264-016-0034-9. Epub 2016 May 20.


Scavenger receptor CD36 mediates inhibition of cholesterol synthesis via activation of the PPARγ/PGC-1α pathway and Insig1/2 expression in hepatocytes.

Rodrigue-Way A, Caron V, Bilodeau S, Keil S, Hassan M, Lévy E, Mitchell GA, Tremblay A.

FASEB J. 2014 Apr;28(4):1910-23. doi: 10.1096/fj.13-240168. Epub 2013 Dec 26.


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