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Items: 1 to 20 of 98

1.

Saturation mutagenesis of Asn152 reveals a substrate selectivity switch in P99 cephalosporinase.

Lefurgy ST, de Jong RM, Cornish VW.

Protein Sci. 2007 Dec;16(12):2636-46.

2.

Structural analysis of the Asn152Gly mutant of P99 cephalosporinase.

Ruble JF, Lefurgy ST, Cornish VW, Powers RA.

Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1189-93. doi: 10.1107/S0907444912024080. Epub 2012 Aug 18.

PMID:
22948919
3.
4.

N152G, -S, and -T substitutions in CMY-2 β-lactamase increase catalytic efficiency for cefoxitin and inactivation rates for tazobactam.

Skalweit MJ, Li M, Conklin BC, Taracila MA, Hutton RA.

Antimicrob Agents Chemother. 2013 Apr;57(4):1596-602. doi: 10.1128/AAC.01334-12. Epub 2013 Jan 14.

5.

Identification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.

Goldberg SD, Iannuccilli W, Nguyen T, Ju J, Cornish VW.

Protein Sci. 2003 Aug;12(8):1633-45.

6.

Role of beta-lactam carboxyl group on binding of penicillins and cephalosporins to class C beta-lactamases.

Fenollar-Ferrer C, Frau J, Donoso J, Muñoz F.

Proteins. 2003 May 15;51(3):442-52.

PMID:
12696055
7.

Critical hydrogen bonding by serine 235 for cephalosporinase activity of TEM-1 beta-lactamase.

Imtiaz U, Manavathu EK, Lerner SA, Mobashery S.

Antimicrob Agents Chemother. 1993 Nov;37(11):2438-42.

8.
10.

Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase.

Drawz SM, Taracila M, Caselli E, Prati F, Bonomo RA.

Protein Sci. 2011 Jun;20(6):941-58. doi: 10.1002/pro.612. Epub 2011 May 3.

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14.

The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation.

Dong J, Lu X, Wei Y, Luo L, Dunaway-Mariano D, Carey PR.

Biochemistry. 2003 Aug 12;42(31):9482-90.

PMID:
12899635
15.

Modifying the specificity and activity of the Enterobacter cloacae P99 beta-lactamase by mutagenesis within an M13 phage vector.

Siemers NO, Yelton DE, Bajorath J, Senter PD.

Biochemistry. 1996 Feb 20;35(7):2104-11.

PMID:
8652552
16.
17.

Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.

Papp-Wallace KM, Taracila M, Hornick JM, Hujer AM, Hujer KM, Distler AM, Endimiani A, Bonomo RA.

Antimicrob Agents Chemother. 2010 Jul;54(7):2867-77. doi: 10.1128/AAC.00197-10. Epub 2010 Apr 26.

18.

Naturally occurring extended-spectrum cephalosporinases in Escherichia coli.

Mammeri H, Poirel L, Fortineau N, Nordmann P.

Antimicrob Agents Chemother. 2006 Jul;50(7):2573-6.

20.

Probing active-site residues of pyranose 2-oxidase from Trametes multicolor by semi-rational protein design.

Salaheddin C, Spadiut O, Ludwig R, Tan TC, Divne C, Haltrich D, Peterbauer C.

Biotechnol J. 2009 Apr;4(4):535-43. doi: 10.1002/biot.200800265.

PMID:
19370721

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