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Items: 1 to 20 of 97

1.

Pivotal role of Smad3 in a mouse model of T cell-mediated hepatitis.

Kremer M, Perry AW, Milton RJ, Rippe RA, Wheeler MD, Hines IN.

Hepatology. 2008 Jan;47(1):113-26.

PMID:
18023023
2.

CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death.

Chen D, McKallip RJ, Zeytun A, Do Y, Lombard C, Robertson JL, Mak TW, Nagarkatti PS, Nagarkatti M.

J Immunol. 2001 May 15;166(10):5889-97.

3.

The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury.

Klein C, Wüstefeld T, Assmus U, Roskams T, Rose-John S, Müller M, Manns MP, Ernst M, Trautwein C.

J Clin Invest. 2005 Apr;115(4):860-9.

4.

Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production.

Lafdil F, Wang H, Park O, Zhang W, Moritoki Y, Yin S, Fu XY, Gershwin ME, Lian ZX, Gao B.

Gastroenterology. 2009 Dec;137(6):2125-35.e1-2. doi: 10.1053/j.gastro.2009.08.004.

5.
6.

Activated farnesoid X receptor attenuates apoptosis and liver injury in autoimmune hepatitis.

Lian F, Wang Y, Xiao Y, Wu X, Xu H, Liang L, Yang X.

Mol Med Rep. 2015 Oct;12(4):5821-7. doi: 10.3892/mmr.2015.4159.

7.

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.

Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S.

Hepatology. 2007 Oct;46(4):1257-70.

PMID:
17657819
8.

Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species.

Black D, Lyman S, Qian T, Lemasters JJ, Rippe RA, Nitta T, Kim JS, Behrns KE.

Biochimie. 2007 Dec;89(12):1464-73.

9.

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.

Murata M, Matsuzaki K, Yoshida K, Sekimoto G, Tahashi Y, Mori S, Uemura Y, Sakaida N, Fujisawa J, Seki T, Kobayashi K, Yokote K, Koike K, Okazaki K.

Hepatology. 2009 Apr;49(4):1203-17. doi: 10.1002/hep.22765.

PMID:
19263472
10.

Transforming growth factor-beta/Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity.

Anthoni M, Fyhrquist-Vanni N, Wolff H, Alenius H, Lauerma A.

Br J Dermatol. 2008 Sep;159(3):546-54. doi: 10.1111/j.1365-2133.2008.08696.x.

11.

Favored T helper 1 response in a mouse model of hepatosteatosis is associated with enhanced T cell-mediated hepatitis.

Kremer M, Hines IN, Milton RJ, Wheeler MD.

Hepatology. 2006 Jul;44(1):216-27.

PMID:
16799967
12.

Impaired liver regeneration and increased oval cell numbers following T cell-mediated hepatitis.

Hines IN, Kremer M, Isayama F, Perry AW, Milton RJ, Black AL, Byrd CL, Wheeler MD.

Hepatology. 2007 Jul;46(1):229-41.

PMID:
17596893
13.

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo.

Jiang JX, Chen X, Serizawa N, Szyndralewiez C, Page P, Schröder K, Brandes RP, Devaraj S, Török NJ.

Free Radic Biol Med. 2012 Jul 15;53(2):289-96. doi: 10.1016/j.freeradbiomed.2012.05.007.

14.
15.

Crucial role of IL-4/STAT6 in T cell-mediated hepatitis: up-regulating eotaxins and IL-5 and recruiting leukocytes.

Jaruga B, Hong F, Sun R, Radaeva S, Gao B.

J Immunol. 2003 Sep 15;171(6):3233-44.

16.

Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.

Matsuzaki K, Murata M, Yoshida K, Sekimoto G, Uemura Y, Sakaida N, Kaibori M, Kamiyama Y, Nishizawa M, Fujisawa J, Okazaki K, Seki T.

Hepatology. 2007 Jul;46(1):48-57.

PMID:
17596875
17.

TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury.

Matsubara T, Tanaka N, Sato M, Kang DW, Krausz KW, Flanders KC, Ikeda K, Luecke H, Wakefield LM, Gonzalez FJ.

J Lipid Res. 2012 Dec;53(12):2698-707. doi: 10.1194/jlr.M031773.

18.

TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2.

Ramesh S, Qi XJ, Wildey GM, Robinson J, Molkentin J, Letterio J, Howe PH.

EMBO Rep. 2008 Oct;9(10):990-7. doi: 10.1038/embor.2008.158.

19.

Suppressor of cytokine signaling 1 protects mice against concanavalin A-induced hepatitis by inhibiting apoptosis.

Torisu T, Nakaya M, Watanabe S, Hashimoto M, Yoshida H, Chinen T, Yoshida R, Okamoto F, Hanada T, Torisu K, Takaesu G, Kobayashi T, Yasukawa H, Yoshimura A.

Hepatology. 2008 May;47(5):1644-54. doi: 10.1002/hep.22214.

PMID:
18393318
20.

HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice.

Kawamura H, Govindarajan S, Aswad F, Machida K, Lai MM, Sung VM, Dennert G.

Hepatology. 2006 Oct;44(4):936-44.

PMID:
17006910

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