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Items: 1 to 20 of 87


Therapeutic implications of leukemic stem cell pathways.

Chumsri S, Matsui W, Burger AM.

Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6549-54. Review.


Effect of transcription-factor concentrations on leukemic stem cells.

Rosenbauer F, Koschmieder S, Steidl U, Tenen DG.

Blood. 2005 Sep 1;106(5):1519-24. Epub 2005 May 24. Review.


Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells.

Wang Y, Liu Y, Tang F, Bernot KM, Schore R, Marcucci G, Caligiuri MA, Zheng P, Liu Y.

Blood. 2014 Aug 14;124(7):1127-35. doi: 10.1182/blood-2013-12-544221. Epub 2014 Jul 3.


Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells.

Chiang MY, Shestova O, Xu L, Aster JC, Pear WS.

Blood. 2013 Feb 7;121(6):905-17. doi: 10.1182/blood-2012-03-416503. Epub 2012 Oct 31.


Self-renewal related signaling in myeloid leukemia stem cells.

Heidel FH, Mar BG, Armstrong SA.

Int J Hematol. 2011 Aug;94(2):109-117. doi: 10.1007/s12185-011-0901-0. Epub 2011 Jul 29. Review.


Small molecule regulation of normal and leukemic stem cells.

Fares I, Rivest-Khan L, Cohen S, Sauvageau G.

Curr Opin Hematol. 2015 Jul;22(4):309-16. doi: 10.1097/MOH.0000000000000151. Review.


Leukemic stem cell frequency: a strong biomarker for clinical outcome in acute myeloid leukemia.

Terwijn M, Zeijlemaker W, Kelder A, Rutten AP, Snel AN, Scholten WJ, Pabst T, Verhoef G, Löwenberg B, Zweegman S, Ossenkoppele GJ, Schuurhuis GJ.

PLoS One. 2014 Sep 22;9(9):e107587. doi: 10.1371/journal.pone.0107587. eCollection 2014.


Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells.

Mahlknecht U, Schönbein C.

Haematologica. 2008 Mar;93(3):443-6. doi: 10.3324/haematol.11796. Epub 2008 Feb 11.


Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cells.

Chakraborty A, White SM, Schaefer TS, Ball ED, Dyer KF, Tweardy DJ.

Blood. 1996 Oct 1;88(7):2442-9.


Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells.

Moore MA, Dorn DC, Schuringa JJ, Chung KY, Morrone G.

Exp Hematol. 2007 Apr;35(4 Suppl 1):105-16.


Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?

Rizo A, Vellenga E, de Haan G, Schuringa JJ.

Hum Mol Genet. 2006 Oct 15;15 Spec No 2:R210-9. Review.


Id2 expression increases with differentiation of human myeloid cells.

Ishiguro A, Spirin KS, Shiohara M, Tobler A, Gombart AF, Israel MA, Norton JD, Koeffler HP.

Blood. 1996 Jun 15;87(12):5225-31.


Deacetylase inhibitors modulate proliferation and self-renewal properties of leukemic stem and progenitor cells.

Romanski A, Schwarz K, Keller M, Wietbrauk S, Vogel A, Roos J, Oancea C, Brill B, Krämer OH, Serve H, Ruthardt M, Bug G.

Cell Cycle. 2012 Sep 1;11(17):3219-26. doi: 10.4161/cc.21565. Epub 2012 Aug 16.


STAT transcription factors in normal and cancer stem cells.

Dorritie KA, Redner RL, Johnson DE.

Adv Biol Regul. 2014 Sep;56:30-44. doi: 10.1016/j.jbior.2014.05.004. Epub 2014 Jun 5. Review.


The leukemic stem cell niche: current concepts and therapeutic opportunities.

Lane SW, Scadden DT, Gilliland DG.

Blood. 2009 Aug 6;114(6):1150-7. doi: 10.1182/blood-2009-01-202606. Epub 2009 Apr 28. Review.


The rarity of ALDH(+) cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients.

Hoang VT, Buss EC, Wang W, Hoffmann I, Raffel S, Zepeda-Moreno A, Baran N, Wuchter P, Eckstein V, Trumpp A, Jauch A, Ho AD, Lutz C.

Int J Cancer. 2015 Aug 1;137(3):525-36. doi: 10.1002/ijc.29410. Epub 2015 Jan 14.


Concise review: genetic dissection of hypoxia signaling pathways in normal and leukemic stem cells.

Gezer D, Vukovic M, Soga T, Pollard PJ, Kranc KR.

Stem Cells. 2014 Jun;32(6):1390-7. doi: 10.1002/stem.1657. Review.


Mechanisms controlling pathogenesis and survival of leukemic stem cells.

Jordan CT, Guzman ML.

Oncogene. 2004 Sep 20;23(43):7178-87. Review.


Pathways involved in the evolution of leukemic stem cells.

Zhang PY, Yang YJ, Fu CM, Xiang LL, Wang Q, Li XL.

Eur Rev Med Pharmacol Sci. 2015 Apr;19(8):1356-63. Review.

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