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Items: 1 to 20 of 189

1.

RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.

Guidez F, Parks S, Wong H, Jovanovic JV, Mays A, Gilkes AF, Mills KI, Guillemin MC, Hobbs RM, Pandolfi PP, de Thé H, Solomon E, Grimwade D.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18694-9. Epub 2007 Nov 13.

2.
3.

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein.

Dong S, Zhu J, Reid A, Strutt P, Guidez F, Zhong HJ, Wang ZY, Licht J, Waxman S, Chomienne C, Chen Z, Zelent A, Chen SJ.

Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3624-9.

4.

Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia.

Hummel JL, Wells RA, Dubé ID, Licht JD, Kamel-Reid S.

Oncogene. 1999 Jan 21;18(3):633-41.

5.

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.

Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG.

Nature. 1998 Feb 19;391(6669):815-8.

PMID:
9486655
6.

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

He LZ, Guidez F, Tribioli C, Peruzzi D, Ruthardt M, Zelent A, Pandolfi PP.

Nat Genet. 1998 Feb;18(2):126-35.

PMID:
9462740
8.

8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation.

Jiao B, Ren ZH, Liu P, Chen LJ, Shi JY, Dong Y, Ablain J, Shi L, Gao L, Hu JP, Ren RB, de Thé H, Chen Z, Chen SJ.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3495-500. doi: 10.1073/pnas.1222863110. Epub 2013 Feb 4.

9.

Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC.

Rice KL, Hormaeche I, Doulatov S, Flatow JM, Grimwade D, Mills KI, Leiva M, Ablain J, Ambardekar C, McConnell MJ, Dick JE, Licht JD.

Blood. 2009 Dec 24;114(27):5499-511. doi: 10.1182/blood-2009-03-206524. Epub 2009 Oct 23.

11.

Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.

Benedetti L, Grignani F, Scicchitano BM, Jetten AM, Diverio D, Lo Coco F, Avvisati G, Gambacorti-Passerini C, Adamo S, Levin AA, Pelicci PG, Nervi C.

Blood. 1996 Mar 1;87(5):1939-50.

PMID:
8634442
12.

Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

Licht JD, Shaknovich R, English MA, Melnick A, Li JY, Reddy JC, Dong S, Chen SJ, Zelent A, Waxman S.

Oncogene. 1996 Jan 18;12(2):323-36.

PMID:
8570209
14.

Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.

Puccetti E, Sennewald B, Fosca-Ferrara F, Boehrer S, Bianchini A, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M.

Hematol J. 2001;2(6):385-92.

PMID:
11920278
15.
16.

Sequence-specific DNA binding and transcriptional regulation by the promyelocytic leukemia zinc finger protein.

Li JY, English MA, Ball HJ, Yeyati PL, Waxman S, Licht JD.

J Biol Chem. 1997 Sep 5;272(36):22447-55.

17.
18.

TBLR1 fuses to retinoid acid receptor α in a variant t(3;17)(q26;q21) translocation of acute promyelocytic leukemia.

Chen Y, Li S, Zhou C, Li C, Ru K, Rao Q, Xing H, Tian Z, Tang K, Mi Y, Wang B, Wang M, Wang J.

Blood. 2014 Aug 7;124(6):936-45. doi: 10.1182/blood-2013-10-528596. Epub 2014 Apr 29.

PMID:
24782508
19.

RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells.

Girard N, Tremblay M, Humbert M, Grondin B, Haman A, Labrecque J, Chen B, Chen Z, Chen SJ, Hoang T.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13522-7. doi: 10.1073/pnas.1310067110. Epub 2013 Jul 29.

20.

CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment.

Park DJ, Chumakov AM, Vuong PT, Chih DY, Gombart AF, Miller WH Jr, Koeffler HP.

J Clin Invest. 1999 May 15;103(10):1399-408.

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